Truksal

Description overdue on 09/11/2014

• Latin name: Truxal
• ATC code: N05AF03
• Active substance: Chlorprothixene (Chlorprothixene)
• Manufacturer: H. Lundbeck A / S (Denmark)

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Truksala (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

Depending on the form of a part Truskala may contain varying amounts of both are active and auxiliary connections.

5 mg. chlorprothixene hydrochloride,   and   lactose monohydrate, croscarmellose sodium, magnesium stearate, talc, copovidone, corn starch, microcrystalline cellulose,   and 85% glycerol contained in one tablet (diameter: 6 mm.), coated with a film of dark brown shell, which includes a dye TM 1030, -171, 172 (Opadry OY-S-9478).

15 mg. hydrochloride chlorprothixene , and croscarmellose sodium, corn starch, talc, 85% glycerol, lactose monohydrate, magnesium stearate, copovidone and microcrystalline cellulose contained in one tablet (diameter: 7 mm.), film-coated brown color, which includes a colorant Opadry OY-S-9478.

25 mg. hydrochloride chlorprothixene , and magnesium stearate, laktolozy monohydrate, copovidone, 85% glycerol, croscarmellose sodium, microcrystalline cellulose and talc It may be contained in a single round and biconvex tablet, a film coating composition which includes red and black iron oxide, titanium dioxide, and macrogol dye Opadry OY-S-9478.

Product form

Truksal   produced in tablet form. The tablets vary in their size, as well as an active dose of the active compound contained in the composition of some form of drug release of the drug.

In a cardboard package may be blisters with 50 or 100 pieces Truksala tablets containing in the chemical composition of the 5, 15 or 25 mg. hydrochloride chlorprothixene .

Pharmacological action

This drug belongs to the group neuroleptics and antipsychotics   drugs. Truksal has on the human body neuroleptic   and simultaneously antipsychotic pharmacological effects .

Pharmacodynamics and pharmacokinetics

Thanks to Truksal   considered derivative thioxanthene , Experts attribute this to the effective preparation neuroleptic drugs .   Antipsychotic effects   as an active drug has active compounds contained in the composition of the drug to affect dopamine receptors .

Truksal these blocks receptors (α1 - adrenergic receptors, the 5-HT2 receptor - receptor and the H1 - histamine receptors) thereby showing their   analgesic , and   antiemetic properties.   Because the drug is rapidly absorbed, the maximum concentration of the drug compounds into the blood is achieved in two hours.

The drug is excreted with urine and feces. Truksal penetrates placenta Ie the drug is released through breast milk.

Indications

Truksal taken at:

• manic states;
• psychoses;
• hyperactivity;
• schizophrenia;
• withdrawal syndrome;
• confusion in old age ;
• depression;
• violation of children's behavior;
• psychosomatic disorders.

In addition, the drug is used in combination with analgesics in complex therapeutic treatment of pain.

Contraindications

Truksal is contraindicated in:

• any form CNS depression For example, alcohol, toxic or narcotic intoxication;
• comatose states ;
• malfunctions hematopoietic system ;
• vascular collapse ;
• pheochromocytoma ;
• hypersensitivity .

Everything else is forbidden to take medication during   breastfeeding And it is forbidden to assign women during pregnancy .

Side effects

Truksal   It has the following side effects:

• dry mouth;
• drowsiness;
• sweating;
• tachycardia;
• disorientation.

The above-mentioned side effects of the drug tend to arise at the beginning of the therapeutic treatment and gradually disappear with time. Before the drug in high doses can be observed dysmenorrhea, hypotension And there are rashes on the skin.

Instructions for use Truksala (method and dosage)

In accordance with the instructions on treatment Truksal mania, schizophrenia   and other psychoses   should begin with a dosage of not more than 100 mg. drug per day. The dose should increase gradually, usually a maximum of 300 mg. in a day.

The dosage of 500 mg. Truksala three times a day for a week will help to remove withdrawal hangover alcoholism   or drug dependence.

Able confusion Elderly patients administered 90 mg. drug per day. With insomnia   You can receive up to 30 mg. Truksala approximately one hour before bedtime. Depressions   and others psychosomatic disorders   treated daily dosage not exceeding 90 mg. When the pain administered to 300 mg. Truksala.

Overdose

If you exceed the dosage Truksala following symptoms may occur:

• convulsions;
• coma;
• drowsiness;
• extrapyramidal syndromes;
• hyperthermia;
• shock;
• hypothermia.

In overdose Truksalom primarily patients washed stomach And then providing support cardiovascular and respiratory systems s symptomatic treatment.

Cooperation

As may increase depressant effects on CNS   a person should not take together with Truksal etanolsoderzhaschie and sedatives , and analgesics, anesthetics, hypnotics and antipsychotic agents of character.

Do not use products containing chlorprothixene, at the same time antiparkinsonian, anticholinergics and antihistamines. It is forbidden to use adrenaline   together with Truksalom avoid tachycardia and hypotension .

Patients with epilepsy while taking the drug dosages need to be adjusted antiepileptics Because this medication helps to reduce convulsive threshold.   Effectiveness Levodopa   reduced when taking Truksala. Extrapyramidal disorders   can occur when sharing the drug and Reserpine, phenothiazines, haloperidol and metoclopramide.

Terms of sale

Leave a prescription.

Storage conditions

Truksal should be stored at 25 ° C out of reach of children.

Shelf life

• Truksala tablets containing 5 mg. active drug components - 3 years;
• tablets containing 15, 25 and 50 mg. substances - 5 years.

Cautions

Precautions Truksal be administered to patients with epilepsy, atherosclerosis,   at Parkinson's disease at diseases of the cardiovascular system At diabetes . hypertrophy and abnormal liver function , and kidney .

During the pregnancy test drug can give a false positive result. In addition, the drug had little effect on QT interval   during elektrokardiogrammnogo   study. It is forbidden to drink alcohol while taking the drug.

During the use of this medication should avoid driving vehicles and performing work related to the maintenance of potentially hazardous machinery.

Analogs Truksala

Match code ATC 4th level:

• Klopiksol
• Chlorprothixene

By analogues include Truksala Chlorprothixene .

During pregnancy (and lactation)

The drug is contraindicated.

Reviews Truksale

While reviews of Truskale forums rather positive, some negative experiences share of the drug. Often, mothers of children with behavioral disorders   negatively expressed regarding this drug. Reviews of doctors about the drug are rare, and are reduced to the fact that he shows in each case a different performance results. In any case, there are both supporters and opponents of the use of this drug.

Price Truksala where to buy

The average price Truksala (packing tablets of 50 mg. Each, 50 pieces) does not exceed 450 rubles.

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