Glycerin

Description overdue on 07/10/2014

• Latin name: Glycerin
• ATC code: A06AG04
• Active substance: Glycerol (Glycerol)
• Manufacturer: Valium, Tver pharmaceutical factory, OAO "Pharmstandard", Russia; PJSC "Phytopharm Corporation" Arterium ", Ukraine

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• Composition
• Description of the release form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use glycerol (dosage regimen)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Glycerine for children
• Newborns
• During pregnancy (and lactation)
• Cautions
• Reviews
• Price, where to buy

Composition

The vial glycerol solution   for external and local application contains 25 grams distilled glycerin (glycerol) .

In part one glycerin suppository rectal   part 1, 44/2, 46 grams glycerol   as active ingredient and auxiliary ingredients: Polyethylene glycol   (polyethylene glycol) in an amount sufficient for the preparation of the suppository mass 1, 53-1, 69/2, 61-2, 89 grams; Acidum stearicum   (acid stearic); Sodium carbonate decahydrate   (sodium carbonate decahydrate).

Description of the release form

Medical glycerol has two dosage forms are:

• Rectal suppositories ;
• solution designed for local and external application .

Suppositories are sharpened torpedo shape, their color close to white. Children's candles are issued a mass of 1, 53-1, 69 gram of, candles for adults have the weight of from 2, 61 up to 2, 89 gram of.

The liquid form of the drug is a syrupy liquid transparent colorless viscous consistency, odorless, with a sweet taste. An aqueous solution of glycerol neutral.

Pharmacological action

Rectal suppositories glycerol   They belong to the group of medicines used to treat constipation.

The solution   belongs to a group of dermatological pharmacotherapeutic agents with emollient and protective action.

Pharmacodynamics and pharmacokinetics

Pure glycerol irritates the skin, but this effect disappears completely when the substance is diluted with water, Vaseline   or lanolin . When used as an external agent, glycerol has dermatoprotektornoe action , Soothes and regenerates the skin.

The antiseptic properties   glycerol allow its use to prevent infection of wounds on the skin infection.

Rectal the use of of glycerol provokes the laxative effect . Means softens the stool, gently irritate the intestinal tract and stimulates the contractility of the walls of the rectum.

Glycerin (for internal use) increases the osmotic and reduce eye and intracranial pressure. Application of liquid glycerol also helps to reduce inward brain edema .

Indications

Pharmacy glycerol shows:

• Rectal   in the form of micro-enemas and suppositories - at constipation   and anal fissures .
• Inwards   - At intracranial pressure At glaucoma . Reye's syndrome   ( acute hepatic encephalopathy . The tool is recommended in combination with other therapeutic measures.
• Externally as applications - to mitigate the excessively dry skin and mucous membranes.

A solution of sodium tetraborate in glycerol (borax) used to treat candidiasis (thrush) . of inflammation of palatine tonsils   ( tonsillitis ), Inflammation of the mucous obochki and pharyngeal lymphoid tissue ( pharyngitis ), As well as for the treatment of pressure sores and fungal infections of the skin affected.

Widespread use in medicine glycerol solution is provided due to its properties: Physico-chemical characteristics of glycerol can increase viscosities, or alternatively, dissolve a particular drug.

Since the substance is characterized as a non-toxic, its use in the pharmaceutical industry. Adds a medical ointments, creams, pastes, glycerol, and prevents them from drying out, possessing properties antisepsis , Disinfects them. As an auxiliary component of glycerol is also added to the tablets.

Made on the basis of glycerol laxative suppositories are used to treat children and adults of various origins constipation, facilitating bowel of its contents.

In folk medicine, a drug often used to treatment of diseases of the throat . Effective cough remedy - lemon, honey and glycerin. For the preparation of this medication take the juice of one lemon and 35-40 ml (2 tablespoons) of glycerol. The mixture was added honey, mixed thoroughly and taken with a strong cough 1 teaspoon of six to eight times per day.

Glycerin in cosmetology. What makes beauty products based on glycerol?

Glycerin for the face is used in the composition of of moisturizing, nourishes and tones the of masks, in the composition of cleans and refreshes lotions, creams and mixtures from the Acne . Thus it benefits the person is difficult to overestimate.

Useful properties of glycerin to the skin expressed in the ability of this material not only moisturize, but also smooth, heal and protect the skin from pollution and penetration microbes .

Face mask with glycerol may include in its composition dried flowers, leaves of plants (eg, aloe or peppermint), berries (both dry and fresh), rice flour, oatmeal, dry clay, mineral water.

One of the most popular is the mask with glycerine and Vitamin E . Vitamin E   Face is considered truly indispensable tool: it prevents premature aging of the skin, smooths wrinkles, eliminates signs of fatigue, and even has the ability to problem skin podlechivat adolescents.

To prepare the masks need to take 10 capsules Vitamin E   and squeeze the contents into the bottle with glycerol (25 ml). Resulting mixture of glycerol and Vitamin E   well shaken and put on pre-cleaned face for 40-60 minutes, then wipe the face with a napkin (no need to wash). The greatest effect was observed for the skin, if you do this procedure before going to bed.

Glycerine mask of wrinkles can also be prepared using as auxiliary components of honey, oatmeal, Vitamin B1   or ascorbic acid .

For the preparation of lotions for the face glycerol mixed with herbal decoctions, infusion of lemon peel, floral cologne. To prepare the mixture is mixed for acne ammonia (20 mL), good cologne (40 mL), water (80 ml), and glycerol (5 ml).

In combination with vitamin C And, more precisely, with its less stable form - L-ascorbic acid Glycerol is used to prepare Antioxidant Serum .

Due to the properties ascorbic acid   stimulate Collagen   in the skin and protect from the adverse effects of UV rays, this serum not only minimizes the number of folds, but also makes it less visible scars on the skin are available.

To cook this remedy, you must to take equal amounts of vitamin C , Vegetable glycerin and distilled water and mix them in a dark glass vial. A thin layer of the serum applied to the face before going to bed and leave it on for the whole night.

Glycerin used in hair shampoos, conditioners and hair masks. This is due to its ability to effectively moisturize, soften and thicken the hair, give them a shine and encourage growth.

Shampoos and hair masks with glycerol as a possible purchase in the store, and prepare yourself. Moreover, having decided to prepare a cosmetic product at home, did not have to puzzle over where to get the ingredients for him: and soap base, and vitamins, and herbal teas can be found in any drugstore.

Apply glycerol and hand care. A simple pharmacological product is the so-called "talker stinking hand" which is a mixture of ammonia and glycerol.

At home, glycerol liquid is prepared by mixing equal proportions of glycerol with ammonia . Massaging a mixture useful not only for skin, but also polish - after only a few treatments nails get a beautiful color and begin to shine.

Glycerin hand can also be used in the composition of the lactic acid potato or masks. Improves the skin of hands and warm baths with starch and glycerol, which are taken to prepare 20 mL of glycerol, 2 tablespoons of starch and 500 ml of warm water. Foot to take until the water starts to cool.

For the legs glycerol is recommended for treating cracked heels and softening rough skin. Heels like a baby - it's a dream of every woman.

However, prolonged exposure to the sun, wearing open shoes and things made of synthetic materials, as well as the lack of care for the skin of feet leads to roughness, flaking and cracking heels.

An effective remedy for rough heels is a mixture of glycerol and acetic acid. For its preparation in the vial of glycerol should be top up with up to the neck of acetic essence. The mixture is shaken in a bubble, and then applied with a cotton swab or cotton sponge on the problem areas.

Before using of glycerol with vinegar for heels, skin of the legs is recommended pre-to steam out and poskresti pedicure brush. After the application of funds for the foot wear plastic bags, and on top of them - the socks. Duration of treatment - from an hour to 40 minutes, but it is best to leave the mixture overnight.

Equally effective for glycerol and heels ammonia . A mixture was prepared as simply as described above, only the ingredients for its preparation - ammonia and glycerin - are taken at a ratio of 1: 1. Mix with ammonia   Foot also recommended to put on the skin before going to bed and leave overnight.

Another simple the recipe of glycerol for heels - this is a recipe mixture, which was composed of glycerin, 10-ti% solution of ammonia, 95% -s' ethyl alcohol and purified water.

Preserved flowers in glycerine

Answering the question "What is glycerin? ", We can say that this tool is somewhat preservative.

His quite often apply as a preservative for meat, wheat grains, erythrocytic mass, pantov of the northern deer and etc .. Also use the glycerol and for the preservation of colors.

There are quite a number of recommendations on how to keep flowers in glycerine. It is important to remember that the flowers with thin leaves and very delicate petals with this method of conservation preserve the appearance is much worse than the plants with a dense leaves and fleshy stems (ie, the method of preserving the bouquet is more suitable for roses and orchids than violets or poppies).

Benefits and harms of glycerol

It is believed that glycerol is used for cosmetic purposes, acts to the detriment of the skin. Following statements are true only in part.

The hygroscopic properties of the material allows it to absorb moisture from the surrounding environment and retain it there, where it is applied. As a result, the skin is formed plenochka finest wet, thanks to which there is the most moisturizing effect.

However, studies have shown that in cases where the humidity does not exceed 65 years% glycerol "sucks" water from the deep layers of the skin (as opposed to take moisture from the air) and keeps it on the skin surface.

That is harmful vegetable glycerin that dry skin dries out even more as the water from the young, healthy cells sucked out to moisten the surface layer of dead cells of the skin.

Thus, the use in cosmetics of glycerol is recommended only when sufficient humidity.

Contraindications

Glycerine candles from constipation are contraindicated in:

• hemorrhoids   in the acute stage;
• Cracks in the anus ;
• of inflammatory and of tumor diseases of the rectum ;
• appendicitis ;
• bleeding ;
• diarrhea ;
• hypersensitivity to the of glycerol.

Admission into the glycerol is contraindicated in diabetes , To people with diseases liver and / or of kidneys, cardio-vascular disorders.

Side effects

Glycerol used in large quantities to provoke tissue dehydration. Furthermore, solutions this means may become the reason allergic reactions , Expressed in the form of burning, irritation of the skin and mucous membranes.

Prolonged use of rectal suppositories can result in irritation rectum   (for its elimination in the intestine, enter 10-15 ml of warm vegetable oil - such as olive or sunflower) and violation of the physiological process of defecation. In rare cases may develop catarrhal proctitis .

Admission into the glycerol solution may cause nausea, vomiting, headache, thirst, Arrhythmia   and hyperglycemic coma . Long-term use leads to dehydration.

Instructions for use glycerol (dosage regimen)

Candles Glycerin: instructions for use

To eliminate constipation   candle with glycerol to be administered into the rectum, one time per day. The optimal time for the introduction of rectal suppository - through a 15-20 minutes after breakfast. Treatment was stopped after the normal intestinal motility.

Liquid Glycerin: instructions for use

How   laxative   liquid glycerin used in pure form or in the form of concentrated solutions, it is also sometimes used as a glycerine-microclysters with soda water.

Inside means receives diluted by mixing in equal proportions with water. The dosage is determined based on the weight of the patient: for each kilogram of the body weight is recommended to take 2-3 ml solution, equivalent to 1-1, 5 grams of the drug in a pure form.

Subsequent techniques means its dosage should be reduced by half. To improve the taste, taking glycerol solution cooled.

External liquid glycerin used as a 84-88% solution, treating it as appropriate the affected skin.

How to use borax glycerine

Many people wonder what the drill with glycerin. Sodium tetraborate   or, as it is called in common, borax - This anesthetic with antibacterial properties which is a salt of strong base and weak boric acid . Instructions on the solution of borax in glycerine recommends the use of this agent for the treatment of:

• candidiasis ;
• colpitis ;
• bedsores ;
• stomatitis   (including in newborn infants);
• cracks in the skin and mucous membranes;
• bacterial lesions of the mucosa and skin.

Borax in glycerin for thrush is particularly effective if the disease is in its early stages. In this case, to treat it may not even require the use of other medications.

It uses the drill is simple enough: a tool applied to a cotton swab and then they smeared the walls of the vagina.

Borax in glycerol at stomatitis   applied topically to the oral cavity rinse, treatment of affected areas of skin and mucous membranes, as well as douches. The dose is established by the attending physician, the treatment lasts for 7 to 10 days.

Overdose

Overdose develops with systematic application glycerol . Its symptoms are expressed in the form of dizziness, confusion, increased dryness in the mouth, a sharp increase in thirst, pronounced dehydration . Arrhythmia . renal failure .

Cooperation

Drug interaction glycerol is not described.

Terms of sale

Over the counter.

Storage conditions

Store in a dry place, protected from light and away from children, at temperatures between 2 and 25 ° C.

Shelf life

For liquid glycerin - 5 years from date of manufacture.

For rectal suppositories - 2 years.

Glycerine for children

Children older than 6 years of age is recommended to use 1 weight 1, 53-1, 69 grams or 2 suppositories weighing from 2, 61 to 2, 89 grams per day.

Candles with glycerin for children aged 2 to 6 years appoint 1 suppository weighing 1, 53-1, 69 grams per day.

Glycerine for newborns

Glycerin suppositories are not recommended for use before the baby is 3 months. However, in cases where it is really necessary to be appointed by candles with glycerol and for newborns.

The tool is not addictive and has no adverse effects on the body as a whole. However, when haphazard pass the application of in unlimited quantities are possible violations of the physiological peristalsis and defecation . enterocolitis . diarrhea drug . bowel obstruction .

Glycerol pregnancy

When pregnancy candles glycerin is one of the safest and most effective means to cope with constipation . Glycerol is not toxic, so the suppository does not harm the health of mother and child.

By the way, effective glycerine candles and after childbirth. They are used for constipation caused by:

• a change in intestinal motility   due to hormonal changes and stress suffering in childbirth;
• hemorrhoids ;
• segmental spasm of the large intestine ;
• psychological fear   defecation   (especially in the birth canal rupture).

Permitted for pregnant women is a tool and a 10% solution   Boers   glycerol which is used to eliminate fungi and treat candidiasis .

Moreover, its application may be even in the early stages of pregnancy, when the use of most other drugs is highly undesirable or even forbidden.

Cautions

Glycerin - what is it?

Glycerol - an organic compound which belongs to the class of substances polyhydric alcohols .

Since compound 3 hydroxyl groups (-OH), it represents a trihydric alcohol, or, in other words, the triol (a compound in which two hydroxyl groups - for example, ethylene - are known as dihydric alcohols or diols).

Being simplest representative group triatomic alcohols, the compound characterized typical for the latest chemical properties.

Substance name in Latin - Glycerinum. Product Name (European Pharmacopoeia) - Glikamed.

Its structural formula is as follows:

CH2 - CH - CH2
| | |
OH OH OH

Chemical molecular formula of the substance: HOCH2-CH (OH) -CH2OH.

Molar mass - 92 094 g / mol.

The widespread nature of the compound in the form of glycerides   (or acyl glycerol

 

oleic acid

  .

constipation

Vitamin E .

  thrush . stomatitis . bedsores . tonsillitis   and pharyngitis .

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