Description overdue on 12/18/2014
- Latin name: Immunoglobulinum humanum anticytomegalovirusum
- ATC code: J06B B09
- Active substance: Human Immunoglobulin antitsitomegalovirusny
- Manufacturer: Biopharma Plasma
- Composition
- Product form
- Pharmacological action
- Pharmacokinetics and pharmacodynamics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
As part of the drug active ingredient is present antitsitomegalovirusny human immunoglobulin And glycine as a stabilizer.
Product form
Produced in a solution contained in vials made of cardboard boxes contained 10 ampoules.
Pharmacological action
Immunoglobulin antitsitomegalovirusny - A biological fraction has a pronounced immunological activity, which is released from human plasma. Active base drugs - are specific to the Cytomegalovirus antibodies - namely, the immunoglobulin G.
Because virusoneytralizuyuschego actions the drug has a specific activity. In addition, it provides immunomodulatory effects as immunoglobulin G drug acts on the body's immune system. As a consequence, there is an increase immunity and increase non-specific resistance.
Pharmacokinetics and pharmacodynamics
No data available.
Indications
Immunoglobulin therapy is indicated for antitsitomegalovirusny cytomegalovirus infection with different clinical manifestations in both children and adults. In particular drug is indicated, if the person observed such diseases and conditions:
- Cytomegalovirus infection in pregnant subject to complicated medical history, drug is given in order to prevent violations of pregnancy.
- Cytomegalovirus infection in non-pregnant women, provided a history of complications, in order to prevent the violations that may occur later in pregnancy.
- Cytomegalovirus infection in pregnant women in the absence of complications in history, in order to prevent complications.
- Manifestations of CMV infection in children during the first years of life and newborn babies who were born infected or who have clinical signs of infection in women.
- Cytomegalovirus infection in adult patients who have marked CNS.
Contraindications
Do not inject the drug to people who have a history marked by heavy allergic reactions after administration of blood protein.
Side effects
Once a patient is entered Immunoglobulin antitsitomegalovirusny In some rare cases, there may be manifestation of hyperemia as local reaction as well as a slight increase in body temperature indicators in the first hours after administration of the solution.
In people with altered reactivity possible manifestation allergic reactions of all kinds. Very rarely can develop anaphylactic shock . Therefore, after receiving the injection the patient must remain under medical supervision for a further 30 minutes.
Instructions for use (method and dosage)
Immunoglobulin antitsitomegalovirusny administered only intramuscularly, intravenous administration is forbidden.
With the purpose of treatment of cytomegalovirus infection in the burdened obstetric history as in pregnant and non-pregnant women, need to enter the contents of one vial 4-5 times. Thus the interval between administrations is about 3 to 5 days.
With the purpose of treatment of cytomegalovirus infection in people suffering from central nervous system lesions, introduced the contents of the vials 3 5 times, and the interval between administration of the drug is 2 days.
In the treatment of cytomegalovirus infection in neonates drug must be administered three times a day at a dose rate of 0, 5 ml per 1 kg of body weight, and the interval between the drug administration should be 2-3 days.
In the treatment of cytomegalovirus infection in children of the first years of life should be given the contents of 1 ampoule 4-5 times, and the interval between injections is 5 days.
Overdose
About overdose data is not available.
Cooperation
It noted the expediency of the combined immunoglobulin Foscarnet or Ganciclovir .
It can not be administered in conjunction with any of the drugs in a single screen.
Terms of sale
In pharmacies sold by prescription.
Storage conditions
Store and transport the drug should be subject to the temperature of 2-8 ° C. Freeze the solution should be.
Shelf life
Store can be 2 years.
Cautions
Sufferers Allergies Or with a history of allergic disease, have a day when they were introduced immunoglobulin, and the next three days to take antihistamines . People who suffer from systemic immunopathological diseases, immune globulin can be administered only on background necessary treatment.
After a course of treatment the patient can be vaccinated with live vaccines only after 2-3 months after completion of treatment.
Babies
Where indicated, it is used to treat infants and children.
During pregnancy and lactation
Clinical experience suggests that the adverse effects on the fetus and the mother's condition does not render the drug. Since immunoglobulin enters the mother's milk, protective antibodies can be transmitted from mother to newborn.
Reviews
Reviews immunoglobulin antitsitomegalovirusnom patients rarely leave, but they noted the effectiveness of its action, especially in the complex treatment.
Price, where to buy
Price package antitsitomegalovirusnogo immunoglobulin (10 vials) is from 7400 rubles.
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