Thursday, May 31, 2018

Oral contraceptives increase the level of women in the eyes of male attractiveness

November 21, 2014

Related Articles:
  • Tropikamid
  • Strix Forte
  • Week combat glaucoma
  • Addiction to computer games can kill
Tweet

 Oral contraceptives increase the level of women in the eyes of male attractiveness  The use of women as a contraceptive hormonal oral contraceptives   It can affect the way the lady appreciates the appeal of a man. Scientists who work in University of Florida , Found that birth control pills increase the degree of male attractiveness in women's eyes.

Through recent research on the subject, experts have determined that the test participants, who at the time of acquaintance with their husbands were protected by oral contraceptives, subsequently disappointed about the appearance of their husbands after being stopped to drink tablets. In addition, during the investigation it was found that, regardless of how attractive women seemed their partners after the cessation of birth control pills quality of sexual life less than happy with the fair sex.

According to researchers, there need to be taken into consideration that the quality of sexual and family relations to a large extent determined by both physical and mental health of people. Therefore, the effect of hormonal agents in this case is understandable. Moreover, contraceptive oral medications can affect the family life both positively and negatively.

Many experts do not recommend for a long time to use it is a means to prevent unwanted conception. For example, according to scientists from the University of California, after three years of oral contraceptives in women increases the risk of manifestation Glaucoma . The study found that in women taking birth control pills for more than 3 years, increases the risk of developing glaucoma in 2, 05 times as compared with the ladies who were protected by this method during a smaller period of time. The relationship of these two factors, experts are planning to install in the process of further research. An eye disease associated with increased levels of Intraocular pressure   and atrophy of the optic nerve in the future. But now, some doctors say that women who use this method of protection, should undergo regular examinations by an ophthalmologist.

Scientists have identified why alcoholics difficult to give up alcohol

November 24, 2014

Related Articles:
  • Smoking makes the human brain less
  • Hemangioma spine
  • Protect against liver cancer run, and from kidney cancer - alcohol
  • Children's nightmares provoke the manifestation of mental disorders
Tweet

 Scientists have identified why alcoholics difficult to give up alcohol  Identify some new facts about alcohol addiction recently, scientists succeeded. In particular, researchers from Harvard Medical School have tried to understand why the people who are already alcoholics, are not able to give up the next portion of alcohol which they are offered.

Experts managed to determine that the regular consumption of alcohol over a long period of time will cause damage to certain areas of the brain - namely, those which determine a person's ability to self-control.

Dependence in this case is absolutely certain: the longer a person abuses alcohol, the damage becomes more serious in the brain, and the man with the passage of time more and more difficult to give up alcohol.

To conduct the experiment, proved such a relationship, the researchers drew alcoholics, having 25 years of "experience" the use of alcohol, as well as those who have a passion for this drink mentioned earlier, but not less than 5 years they live a sober life. Also involved in the study and control group the absolute teetotalers.

After MRI study , Experts were able to detect the presence of white matter lesions in the frontal lobes of the brain in those who are alcoholics now or have been dependent on alcohol at the time. It is in the frontal lobe of the human brain are the processes that determine the thinking and attitude of man to certain things. Therefore, it is often the behavior of alcohol-dependent people celebrated a number of oddities and expressed irresponsibility.


Meanwhile, doctors determined that the most dangerous to health are not spirits, and those that contain a relatively small number of degrees. For low-alcohol beverages a person can eat uncontrollably, believing that such alcohol is safe. Scientists say that people very quickly get used to the beer, which is, moreover, beer lovers are always a lot of high-calorie snack foods. Even more dangerous for the body are low-alcohol cocktails, a part of which contains some alcohol and caffeine. Such a mixture of extremely negative effect on the kidneys and liver, and also creates a false impression, forcing a person to consider himself sober.

No less harm to the body brings champagne, if you drink it in large quantities. Carbon dioxide contained in it, is very rapid intoxication and, moreover, stimulates the processes of active putrefaction of food in the intestines.

The optimal alcohol-drink physicians consider quality wine. But use it only occasionally and in small doses.

Walnut prevents prostate cancer

November 17, 2014

Related Articles:
  • High sugar levels may lead to cancer
  • Prostate Cancer Gene
  • Doctors transplanted artificial organ
  • Injections Neovir
Tweet

 Walnut prevents prostate cancer  Use walnuts for the human body is undeniable. But the most "lean" on this delicious product, scientists recommend men. After a few days ago, scientists from the University of California announced the results of studies that suggest that the inclusion in the daily diet of a few walnuts or a small amount of peanut butter you can prevent the development of prostate cancer   men. Experts were able to prove the benefit of such a power, conducting research in experimental animals.

Over the 18 weeks of the study of laboratory mice were given food as peanut butter, whole walnuts or fat composition which resembles the fat contained in them. When the researchers examined the experimental rodents, it noted that the nuts have anti-cancer effects, reduce the content of harmful organism cholesterol . Moreover, when the constant use of the valuable product's sensitivity to insulin increases, thereby reducing the likelihood of Diabetes .

This effect experts explain the fact that nuts contain quite a phenomenal amount of useful and necessary body substances, in particular, omega-3 Protecting against the development of cancer diseases as well as diseases of the heart and blood vessels. In addition, the regular use of these gifts of nature reduced levels of the hormone IGF-1 levels, which also reduces the likelihood of developing breast cancer and prostate cancer.


Therefore, in spite of the general support for the principles of a healthy lifestyle and exclusion from the diet of fatty food, experts recommend eating nuts every day. At the same time, scientists have noted that most of their "merit" is not in the content of omega-3 fatty acids and a unique combination of these and other elements, which is only present in walnuts.

Previously already we published the results of studies showing that the useful product is able to suspend the pathological processes in the brain, which then provoke the development of a person Alzheimer . In addition, nuts are slow unwanted human aging process, strengthen the resistance of the immune system and improve memory. However, the high calorific value of this unique product is not necessary to forget, too: 100 g of kernels - as many as 650 calories.

Coraxan

Description overdue on 06/17/2014

  • Latin name: Coraxan
  • ATC code: S01EB17
  • Active substance: Ivabradine (Ivabradine)
  • Manufacturer: "Servier Laboratories Industry", France
Photos of the drug
Tweet
  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications
  • Contraindications
  • Side effects
  • Instructions for use Coraxan (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Cautions
  • Analogs
  • During pregnancy (and lactation)
  • Reviews
  • Price, where to buy

 Coraxan

Composition

The amount of auxiliary substances hardly differ in various forms of release of the drug, i.e. dosage corresponds tablets excipients and 5, and 7.5 mg ivabradine :

  • lactose monohydrate - 62 mg;
  • Corn starch - 20 mg;
  • maltodextrin   - 10 mg;
  • magnesium stearate - 0.5 mg;
  • Anhydrous colloidal silica   - 0.2 mg.

Sheath Coraxan each tablet comprises:

  • hypromellose - 1.5 mg;
  • dioxide Titanium   (E 171) - 0.26 mg;
  • Macrogol 6000 - 0.09 mg;
  • magnesium stearate - 0.087 mg;
  • yellow dye oxide gland   (E 172) - 0.015 mg;
  • pigment red iron oxide (E 172) - 0.00485 mg.

Product form

Find the drug can be in two variations:

  • Oval, biconvex tablets covered with orange-pink tape with marks on both sides (one "-" and the next number "5"). The dosage of active ingredient - 5 mg.
  • Triangular tablet with orange-pink film and engraved on opposite sides: on the one "-" on the other "7.5", which means that 7.5 mg of the main active component.

Pharmacological action

Medicine Coraxan - is antianginal agent, that is a pharmacological drug that prevents the development of angina   (a disease in Latin sounds like " angina pectoralis ", Hence the name of the pharmaceutical group).

The mechanism of action depends on the biologically active ingredient - ivabradine . The substance is a specific selective If-channel blocker of the sinoatrial node (initiating link excitement conduction system of the heart). In this way ivabradine   helps stabilize the spontaneous depolarization during diastole and normalizes heart rate .


Through clinical studies, it was noted the main pharmacological advantage Coraxan compared with other antianginal drugs. The decrease in heart rate is   dose-dependent factor   when conservative therapy with this drug. That is, by increasing the constant daily dose of   40 mg / day , Therapeutic effectiveness takes the form of a plateau, which greatly reduces the possibility of reducing the rate to 40 beats per minute (pathological bradycardia).

A positive feature of the drug is the lack of influence on myocardial contractility (negative inotropic effect is potentiated). Also Coraxan not affect:

  • ventricular repolarization;
  • intracardiac conduction infarction;
  • atrioventricular excitation pause;
  • corrected QT interval on the electrocardiogram.

In the human body there are channels that the chemical structure are similar to the If. These are in education conjunctiva and called Ih-TV . They take part in a change of visual perception of the retina in response to bright light stimuli. It is in the systemic circulation ivabradine can get to the eye and to work on these formations. In this case, a phenomenon is observed photopsias   (transient distortion svetovospriyatiya human eye to a limited field of view) in response to a trigger, for example, rapid change of the brightness of ambient light.

Pharmacodynamics and pharmacokinetics

The drug is recommended for use in conjunction with Food As food increases the concentration in plasma of systemic circulation from 20 to 30 percent, which is manifested in the form of a complete drug action. That is, due to a prolonged absorption (food increases the time period is 1 hour), the effectiveness of the drug increases significantly.

Getting into the systemic circulation, 70 percent ivabradine bound to plasma proteins, which are delivered to sinoarterialnogo node conduction system of the heart. Metabolised   drug predominantly in the liver and intestine by the action cytochromes .

Evacuated from the body drug kidney . The half-life of the drug is 2:00, however, the effective half-life (the time period when the effectiveness of the biologically active component is equal to half of the original) - 11 hours. Renal clearance ivabradine - 70 ml / min and the total body clearance is maintained at 400 ml / min.

Linearity Coraxan pharmacokinetic activity observed in the concentration range of active ingredient from 0.5 to 24 mg.

Indications

  • Stable angina   (in case of intolerance or contraindications to pharmacological absolute drugs of beta-blockers);
  • congestive heart failure   (if sinus rhythm and heart rate remains at 70 beats per minute);
  • symptomatic treatment of angina   (Improved sanitation measures to reduce the demand of the heart muscle of oxygen);
  • coronary artery disease   (in the treatment and prevention courses for the normalization of the rhythm and frequency of contractions of the myocardium).

Contraindications

Do not use Coraxan in the scheme of conservative treatment anginal attacks If available:

  • individual hypersensitivity or intolerance to existing components of the drug;
  • bradycardia   below 60 beats per minute;
  • sharp myocardial infarction ;
  • cardiogenic shock ;
  • kidney or liver failure;
  • hypotension   (systolic blood pressure below 90 mm Hg, and diastolic - less than 50 mm Hg);
  • complete blockade of the sinoatrial node ;
  • artificial pacemaker maladaptive nature (with constant impulses);
  • Children up to age 18 years (clinicians do not have information about the use of the drug in a given time period of the individual human development).

Also, there are a number of situations where taking Coraxan be therapeutic departments under the strict supervision of medical personnel in order to avoid the consequences of adverse and unexpected reactions:

  • congenital long QT syndrome ;
  • recently transferred ischemic cerebral stroke ;
  • retinitis pigmentosa eye;
  • atrioventricular block   second degree;
  • the simultaneous use of drugs that block potassium pumps slow, lengthening the interval QT, inhibit or inhibits the action of cytochrome gastrointestinal tract.

Side effects

Clinical studies suggest that adverse reactions of the human body to pharmacological drugs - it a dose-dependent effect . Since elevated concentrations of the active drug in the central and peripheral blood flow can be observed:

  • photopsia   - Change svetovospriyatiya in a limited field of view, which is run quickly dimmed lighting;
  • subjective sensation of heart;
  • atrioventricular block   I-III;
  • syndrome acquired sinus;
  • Atrial fibrillation ;
  • severe headache, especially in the first month of the conservative drug therapy;
  • allergic reactions   ( itching . erythema . hives . angioedema );
  • fatigue, malaise, constant drowsiness.

Instructions for use Coraxan (method and dosage)

The drug should be used during the meal, so the coefficient of efficiency of the active ingredient increases several times. The daily dose can be divided into two times: in the morning for breakfast and evening - for dinner. The average amount of the drug is 2 tablets (with a concentration ivabradine - 5 mg) per day, but, depending on the dosage of the therapeutic effect can be increased. In this case, after 3-4 weeks of conservative treatment regimen is changed to 2 tablets with a concentration of active ingredient - 7.5 mg.

Instructions for use Coraxan also allows for side effects and contraindications to receiving drug. First of all, if after development signs of bradycardia   (constant fatigue, dizziness, decreased blood pressure to pathological figures) lower dosage does not contribute to the development of a therapeutic effect, the treatment according to the pharmaceutical preparation is stopped immediately.

It should be very careful in the rehabilitation of older patients. Treatment of the age group over 75 years carried out in a special way - starting dose is half a tablet (based on the mass balance - about 2.5 mg ivabradine) and increases the daily amount of the drug to 5 mg only if signs of a stable and benign conservative therapy.

Overdose

In case of overdose there is a pharmacological drug resistant, do not respond to conventional methods bradycardia . To eliminate the state of high concentration of drug in the systemic circulation should be applied effector antagonists Coraxan - beta-agonists . Used primarily selective drugs that interact only with the cardiac muscle, but in urgent conditions can be applied to non-selective agents. With the urgent need to overdose can be treated surgically - to insert a temporary artificial pacemaker heart rate.

Cooperation

During conservative treatment coraxan avoid inclusion in the dosage regimen, which prolong the QT segment Electrocardiogram as Ivabradine, the main active component of the tablets may cause an additional increase in the segment and the slowing of the heart rate. When absolute terms the use of drugs such as Quinidine . Amiodarone . Sotalol . Erythromycin . Pimozide , Is carried out day and night monitoring of the electrocardiogram in special therapeutic departments.

Precautions can be used nekaliysberegayuschie diuretics   (group consisting of thiazides and "loop" diuretics) as hypokalemia   (the result of joint action Coraxan and pharmacological agents which increase urine output) can lead to severe arrhythmias That in combination with bradycardia or long QT syndrome directly faces undesirable side effects for treating a patient or even fatal. Because boost mocheproduktsiyu urination or recommended under the close supervision of qualified medical personnel.

Definitely contraindicated simultaneous use Coraxan and the following list of drugs:

  • pharmacological agents that act on the hepatic cytochrome ;
  • antifungals of the azole group (e.g. ketoconazole   or itraconazole );
  • antibiotics related to macrolides ( clarithromycin . erythromycin . telithromycin ) Or a group rifampicin ;
  • protease inhibitors of human immunodeficiency virus;
  • strong antidepressants   (especially nefazodone );
  • sedatives mood stabilizers   (St. John's wort)
  • certain drugs for anesthesia (in particular barbiturates ).

An interesting feature of the primary active ingredient, ivabradine It is to increase the concentration in the systemic circulation according to the drunk grapefruit juice . This natural drink is capable of increasing the relative amount of the active ingredient in twice that clearly requires a rational correction ration during the therapeutic course of treatment.

Terms of sale

Coraxan in pharmacy dispensed only receptor Form.

Storage conditions

Coraxan-saving medication should be in a warm, dry place out of reach of young children.

Shelf life

3 years.

Cautions

Coraxan used to stabilize sinus rhythm and prevention of angina, but the pharmacological activity of the drug to zero if you use it on the background tachycardia . Atrial Fibrillation   or ventricular flutter . In these situations, ivabradine As the main biologically active component of the drug will not have a therapeutic effect, on the contrary, the material may worsen the patient's condition at Heart Failure   such genesis.

Turning Coraxan in the course of medical treatment is not recommended if there is a need for a comprehensive pharmacological therapy because it can correct the safety profile (risk of side effects or adverse reactions increases) due to indirect interaction of the components. The drug should not be used in conjunction with calcium channel blockers or dihydropyridine derivatives, which slows the heart rate. In particular, Verapamil . Diltiazem   or Amlodipine   alter the safety profile of the treatment largely because they avoid simultaneous reception coraxan.

Analogs Coraxan

Analogs Coraxan represented only active substance in its pure form, that is kneaded in the conservative treatment of the drug can only be Ivabradine   hydrochloride or the active component. Because the price is not much different analogues of the market value Coraxan and is about 900-1000 rubles in the Russian Federation. In Ukraine, the spread of ivabradine have not gained wide popularity because it could not be found in the pharmacy.

During pregnancy and lactation

Currently, there is a significant lack of information on the use of the drug during pregnancy and / or lactation, but in preclinical studies it has been found embryotoxic and teratogenic. Because the drug is now forbidden to receive in such a critical period of life of women.

Reviews coraxan

Reviews coraxan mostly positive, because the drug normalizes the heart muscle of unknown etiology, that is, when the cause is unknown to the physician. The drug is also called " lifeline "As Coraxan helps when beta-blockers did not have the proper therapeutic effect and does not lead to myocardial contraction rhythm sinus.

Among the negative impressions after conservative rehabilitation is most common severity of side effects of the visual apparatus. Many complain of a strong photopsias Which significantly affects the quality of life of patients.

Reviews of doctors mostly approve of the use of Coraxan, because the drug is the only adequate treatment of choice in many situations where other pharmacological products are unable to help the patient. Adverse reactions on the part of the body is recommended to stop medication as often returned to remove the drug and symptoms of the underlying disease.

Price Coraxan

Price Coraxan 5 mg in Ukraine is 240 hryvnia, which significantly distinguishes the drug among other anti-anginal drugs on the pharmacy shelf. In the Russian Federation, the cost Korasan 5 mg is even higher - it is about 1000 rubles. Because the medicine is best to book in online pharmacies even with the services delivery it is considerably cheaper.

Get the best price and buy

Cooking food at home is bad for health?

December 16, 2014

Related Articles:
  • Reviews of preparation Betalok
  • Price Concor AM 10 +10
  • Fever in children
  • Two meals a day promotes weight loss
Tweet

 Cooking food at home is bad for health?  Traditionally, people believe that home-made food and, consequently, the habit of cooking at home instead of buying ready-made food, it is more useful. Nevertheless, even in this matter is not really all so clearly. According to the researchers, who work at the University of Rush (United States), very often foodies who cook at home, so passionate about the process of improving the food that is added to a wide variety of food sauces and other ingredients that are harmful to human health.

Experts recently conducted a detailed analysis of the information relating to about 3 thousand women. Taken into consideration data about how much time the ladies spent to prepare meals, as well as details about the state of their organisms. Be particularly careful to scientists interested in the development of Metabolic syndrome , So that a person increases the probability of vascular disease, heart, diabetes. Signs of metabolic syndrome is obesity As well as a high level of cholesterol .

It was found that the most common symptoms of the metabolic syndrome were found in women who spend a lot of time to cook a meal at home kitchen. Scientists note that the preparation of meals at home people often use excessive amounts of oil, fat and salt. Besides triggered a psychological factor: spending a lot of time and effort to prepare lunch or dinner, people have a certain way considers itself obliged to eat everything to the last crumb. In the process of cooking the mistress, of course, constantly trying the food, which also contributes to weight gain.


According to experts, the most optimal method of supply - is to buy a ready-made dishes made from high-quality and healthy products. It is desirable to choose the dishes that are sold in batches, which will prevent the possibility of overeating.

We should not forget that in the human diet should have no place large amounts of salt. According to experts from the Welsh Centre of preventive, epidemiological and clinical studies, if products with a high content of salt appear on the table of the consumer too often, the risk of his headaches increased by 30%.

Doctors say that the use of a day more than 8 grams of salt it can adversely affect the condition of the body, in particular, to provoke a manifestation headaches . In addition, salty foods leads to increased   Blood Pressure . A can worsen kidney function in the presence of a daily diet is greater than 4, 7 grams of salt. Therefore, experts strongly advised to review their habits in favor of healthy food.

The lack of testosterone affects the general condition of the male body

December 1, 2014

Related Articles:
  • Use of drugs in IVF may result in an increase in genetic anomalies and the birth of a sick child
  • Sleep apnea
  • The nature of the child depends on the mother's stress during pregnancy
  • Sex Hormones
Tweet

 The lack of testosterone affects the general condition of the male body  If a man has reduced the level of Testosterone   in the body, it not only lowers his libido but also causes poor memory, loss of energy and even provokes the development of diseases.

According to experts, reduction of this hormone in the male body leads to fatigue, Development Muscular Dystrophy , Hair loss. A man becomes irritable, gaining extra weight, he complains of memory loss. In addition, testosterone deficiency occurs more pronounced tendency to   Diseases of the heart and blood vessels . osteoporosis . diabetes .

At the same time, doctors strongly recommend to pay attention to the level of testosterone in the body, even the young men. If earlier the lack of male hormone produced by the adrenal glands, observed more frequently in the stronger sex after the age of 30, but now this problem is relevant for young people.

Meanwhile, scientists from the United States recently tried to debunk the theory that testosterone determines the success of the athletes. According to experts, "merit" of testosterone in sport solely in the fact that it increases the athlete's will to victory.

During the study, researchers measured the levels of this hormone in athletes, and then looked at their results in competitions. After comparing these data experts have concluded that the increase of testosterone does not affect the results in sports.


However, a role in the sport male hormone still acts out, stimulating the desire to win and creating a positive psychological mood. Moreover, due to this substance athlete can quickly gain muscle mass. Please note that the content of testosterone in the body decreases as a result of poor diet, drinking, standing stresses   and other bad habits.

Utrozhestan

Description overdue on 17.05.2012

Related Articles:
  • Reviews sintomitsina acne
  • Price sumatriptan
  • Infertility Treatment
  • Ortofen, instructions for use
Tweet

 Utrozhestan  The hormone of the corpus luteum, progestogen. The active substance is progesterone. The principle impact of the drug based on the binding of the base material with progesterone receptors which are located on the target organs, following penetration into the nucleus and activate DNA, RNA stimulation. Utrozhestan in secretory phase facilitates the transition of the mucosal wall of the uterus proliferation (under the influence of the follicular hormone). After the onset of fertilization drug facilitates the transition of the mucous wall of the uterus in a state that is required for the development of the egg. Utrozhestan reduces the severity of muscle contractility and excitability of the fallopian tubes, uterine wall, the drug stimulates the formation of terminal elements in the mammary glands. The drug increases the concentration of basal and stimulated insulin Increases glucose utilization increases fat reserves proteinlipazu stimulates, increases the production of aldosterone promotes accumulation of glycogen in the liver system. In large doses suppresses the production of pituitary Utrozhestan gonadotropins , And in small doses, on the contrary, it accelerates. The drug increases the excretion of nitrogen with urination, reduces the severity of azotemia, induces lactation, activates the process of growth of secretory acini department in the mammary glands. Utrozhestan available in capsule form.

Indications:

Utrozhestan prescribed for fibrocystic mastopathy , Premenstrual syndrome, during Menopause   as the progestogen component in combined hormone replacement therapy with estrogen. When nonfunctioning ovaries, complete lack of progesterone at   postmenopausal , Menopause, premature menopause, endometriosis, for the prevention of uterine fibroids, endocrine infertility, miscarriage threat Utrozhestan administered vaginally.


Contraindications:

Utrozhestan not appoint a tendency to   thrombosis , Hepatic pathology system, acute forms thromboembolic disorders , Phlebitis, with porphyria, incomplete abortion, bleeding from the reproductive system of unknown origin. With   diabetes , Hyperlipoproteinemia, depression, chronic renal failure, hypertension, diseases of the cardiovascular system, breastfeeding, migraine drug prescribed after consulting experts. Utrozhestan pregnancy used with caution.

Side effect:

Reduction of the menstrual cycle, drowsiness, allergic reactions, intermenstrual bleeding, transient dizziness.

Mode of application:

Utrozhestan take before going to bed in the evening. With dysmenorrhea , Premenstrual syndrome, pre-menopausal women, fibrocystic breast Utrozhestan take 10 days to 200-300 mg 17 to 26 days of the cycle .  When menopause when hormone replacement therapy in patients receiving estrogens take 200 mg a day for 10-12 days .  When egg donation progesterone intravaginal use of estrogen therapy on the background 13 and 14 days of the cycle, 100 mg / day, then twice a day at 100 mg .  To maintain the luteal phase during IVF drug prescribed from the day of hCG injection of 400-600 mg per day up to 12 weeks of pregnancy .  When infertility caused by disorders of the corpus luteum, in induced or spontaneous menstrual cycle to maintain the luteal phase of the preparation is applied to the 17 day cycle at 200-300 mg daily for 10 days .  Utrozhestan during pregnancy, menstruation delay prescribed by the standard scheme .  For the prevention of and the threat of an abortion drug is administered before 12 weeks of pregnancy, twice a day for 100-200 mg .

Special instructions:

Utrozhestan does not apply to Contraception . Because of the risk of liver disease is recommended to be careful in appointing a drug in the 2, 3 trimester. The drug affects the concentration, driving a vehicle.

Drug Interactions:

Utrozhestan reduces the effectiveness of prolactin Oxytocin .

Monday, May 28, 2018

Immunoglobulin antitsitomegalovirusny

Description overdue on 12/18/2014

  • Latin name: Immunoglobulinum humanum anticytomegalovirusum
  • ATC code: J06B B09
  • Active substance: Human Immunoglobulin antitsitomegalovirusny
  • Manufacturer: Biopharma Plasma
Photos of the drug
Tweet
  • Composition
  • Product form
  • Pharmacological action
  • Pharmacokinetics and pharmacodynamics
  • Indications
  • Contraindications
  • Side effects
  • Instructions for use (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Cautions
  • Babies
  • During pregnancy (and lactation)
  • Reviews
  • Price, where to buy

 Immunoglobulin antitsitomegalovirusny

Composition

As part of the drug active ingredient is present   antitsitomegalovirusny human immunoglobulin And glycine as a stabilizer.

Product form

Produced in a solution contained in vials made of cardboard boxes contained 10 ampoules.

Pharmacological action

Immunoglobulin antitsitomegalovirusny   - A biological fraction has a pronounced immunological activity, which is released from human plasma. Active base drugs - are specific to the Cytomegalovirus antibodies - namely, the immunoglobulin G.

Because virusoneytralizuyuschego actions the drug has a specific activity. In addition, it provides immunomodulatory effects as immunoglobulin G drug acts on the body's immune system. As a consequence, there is an increase immunity and increase non-specific resistance.

Pharmacokinetics and pharmacodynamics

No data available.

Indications

Immunoglobulin therapy is indicated for antitsitomegalovirusny   cytomegalovirus infection   with different clinical manifestations in both children and adults. In particular drug is indicated, if the person observed such diseases and conditions:

  • Cytomegalovirus infection in pregnant   subject to complicated medical history, drug is given in order to prevent violations of pregnancy.
  • Cytomegalovirus infection in non-pregnant women, provided a history of complications, in order to prevent the violations that may occur later in pregnancy.
  • Cytomegalovirus infection in pregnant women in the absence of complications in history, in order to prevent complications.
  • Manifestations of CMV infection in children during the first years of life and newborn babies who were born infected or who have clinical signs of infection in women.
  • Cytomegalovirus infection in adult patients who have marked CNS.

Contraindications

Do not inject the drug to people who have a history marked by heavy   allergic reactions   after administration of blood protein.

Side effects

Once a patient is entered Immunoglobulin antitsitomegalovirusny In some rare cases, there may be manifestation of hyperemia   as local reaction as well as a slight increase in body temperature indicators in the first hours after administration of the solution.


In people with altered reactivity possible manifestation allergic reactions   of all kinds. Very rarely can develop anaphylactic shock . Therefore, after receiving the injection the patient must remain under medical supervision for a further 30 minutes.

Instructions for use (method and dosage)

Immunoglobulin antitsitomegalovirusny administered only intramuscularly, intravenous administration is forbidden.

With the purpose of treatment of cytomegalovirus infection in the burdened obstetric history as in pregnant and non-pregnant women, need to enter the contents of one vial 4-5 times. Thus the interval between administrations is about 3 to 5 days.

With the purpose of treatment of cytomegalovirus infection in people suffering from central nervous system lesions, introduced the contents of the vials 3 5 times, and the interval between administration of the drug is 2 days.

In the treatment of cytomegalovirus infection in neonates drug must be administered three times a day at a dose rate of 0, 5 ml per 1 kg of body weight, and the interval between the drug administration should be 2-3 days.

In the treatment of cytomegalovirus infection in children of the first years of life should be given the contents of 1 ampoule 4-5 times, and the interval between injections is 5 days.

Overdose

About overdose data is not available.

Cooperation

It noted the expediency of the combined immunoglobulin Foscarnet   or Ganciclovir .

It can not be administered in conjunction with any of the drugs in a single screen.

Terms of sale

In pharmacies sold by prescription.

Storage conditions

Store and transport the drug should be subject to the temperature of 2-8 ° C. Freeze the solution should be.

Shelf life

Store can be 2 years.

Cautions

Sufferers Allergies Or with a history of allergic disease, have a day when they were introduced immunoglobulin, and the next three days to take antihistamines . People who suffer from systemic immunopathological diseases, immune globulin can be administered only on background necessary treatment.

After a course of treatment the patient can be vaccinated with live vaccines only after 2-3 months after completion of treatment.

Babies

Where indicated, it is used to treat infants and children.

During pregnancy and lactation

Clinical experience suggests that the adverse effects on the fetus and the mother's condition does not render the drug. Since immunoglobulin enters the mother's milk, protective antibodies can be transmitted from mother to newborn.

Reviews

Reviews immunoglobulin antitsitomegalovirusnom patients rarely leave, but they noted the effectiveness of its action, especially in the complex treatment.

Price, where to buy

Price package antitsitomegalovirusnogo immunoglobulin (10 vials) is from 7400 rubles.

Get the best price and buy

Smecta

Description overdue on 07.10.2011

Related Articles:
  • Instructions for use tablets Solkoseril
  • Hofitol in early pregnancy
  • Levolet 500
  • Reviews dihydroquercetin Evalar
Tweet

 Smecta  Main, an active substance - dioctahedral smectite . Smecta is of natural origin, has adsorbing effect . The preparation stabilizes the mucosal barrier, increases the amount of mucus smectite forms mucus glycoproteins with polyvalent connection.

Smectite has pronounced selective sorption properties, which ensures its discoid-crystal structure . The drug adsorbs bacteria and viruses found in the lumen of the gastrointestinal tract.

Dosage Form:

Powder for suspension. Ingested orally.

Indications:

Allergic, drug, infectious diarrhea   The drug is effective when receiving low-quality food, eating disorders. Smecta effectively cope with heartburn . bloating , Discomfort and other symptoms dyspepsia That accompany various diseases of the digestive tract.

Contraindications:

Fructose intolerance, ileus , Sucrose izomaltaznaya deficiency, glucose-galactose malabsorption, allergies.

Side effect:


constipation Allergies.

Mode of application:

One bag contains 3 grams of the drug Smecta. The powder was diluted in water and stirred. Take 3 times a day. Newborns should not take more than 3 grams of the drug per day. For children, the powder is dissolved in baby bottles (volume 50 ml) was stirred with a semi-liquid products (baby food, fruit compote, mashed potatoes, cereal, etc.). Distribute several doses throughout the day.

Special instructions:

Smecta for newborns at recommended doses has no negative impact on the child's digestion. The drug acts locally, without penetrating into the bloodstream. The body of the child smectite absorbs harmful substances, gases and protects the mucous membrane of the intestinal wall, does not deprive the baby of nutrients and minerals. Smectite interacts with mucus in the intestine and prevents its rapid removal. Smecta is not absorbed by the body, so it does not have a negative impact on the body. All the components of the drug being evacuated from the intestine of the child in its original condition.

If the child has severe diarrhea the first dose of the smectite can be doubled. Smecta eliminates the factor causing diarrhea, stops diarrhea. The product prints from the children's intestines harmful bacteria, their metabolic products. Possible allergies, so you need to carefully monitor the state of health of the child during treatment.

If after three days of treatment drugs Smecta improvement does not come, you must see a doctor. When vomiting and temperature should stop taking the drug. Smecta during pregnancy has no effect on the fetus and the woman's condition.

Drug Interactions:

Smecta reduces the absorption of other drugs (explained). It is recommended to refuse to accept other drugs while taking smectite, or take medication at intervals of not less than 1 hour.

Phytochemicals that prevent cancer

June 14, 2011

Related Articles:
  • Argentine beetle cure illness
  • High sugar levels may lead to cancer
  • New diagnosis of prostate cancer
  • Training and caffeine against skin cancer
Tweet

 Phytochemicals that prevent cancer  Eliptidy   - A group of substances of vegetable origin, has a therapeutic and prophylactic effects on various types of cancer. The mechanism of eliptidov still not fully understood. There are suggestions that, getting into the body, they are converted into a substance which acts directly on the cancerous cells and reducing the probability of occurrence of cancer. It is proved that contained eliptitsine enzymes have a therapeutic effect on some species breast cancers   women, as well as slow down the development of skin cancer.

Indole - Another substance of plant origin that has a prophylactic effect against cancer. It is found in Brussels sprouts, cauliflower and cabbage. Also indole these vegetables contain many other nutrients, which also play an important role in the prevention of malignant tumors. For example, coumarins reduce various carcinogenic effects on the stomach, thereby help remove carcinogens from the body. It should also be noted that some substances contained in cabbage, helps not only to prevent entry of carcinogens in the body, but also help to bring already trapped in the body carcinogens.

One of the most simple and effective cancer prevention Is the inclusion in the human diet fruits and vegetables. AT vegetables and fruits are rich in substances that are getting into the human digestive tract, because of its fibrous component, clean it. It is known that the daily consumption of carrots, apples, it is a good protection against cancer of the rectum.


 Phytochemicals that prevent cancer  In the study plant and the content is open all new and new ways for the prevention of various cancers, and for the health of the whole person.

Through research, over time people drank goat's milk and ate some plant species that contain toxic pirolizidinovye Alkaloids , And found that their bodies are capable of the metabolism process foreign substances. Changes were observed in monooxygenases which are involved in chemical reactions to carcinogens, and can make the assumption that this alkaloid can affect processes that prevent the emergence of tumor.

Summarizing, it can be concluded that substances of plant origin perform an important protective function in the body, it concerns in particular the prevention and treatment of various cancers.

Pharmatex

Description overdue on 04/28/2014

  • Latin name: Pharmatex
  • ATC code: G02BB
  • Active substance: BAK (Benzalkonium chloride)
  • Manufacturer: Innothera Chouzy, France
Photos of the drug
Tweet
  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications
  • Contraindications
  • Side effects
  • Instructions on Pharmatex
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Analogs
  • Reviews
  • Price, where to buy

 Pharmatex

Composition

Per swab   for 60 mg benzalkonium chloride . Excipients: glycol stearate, citric acid, lavender oil, poliglekol, purified water. Each swab is provided polivinilformaldegidnogo impregnation (5 g of a cream).

On the one candle vaginal It accounts for 18.9 mg of benzalkonium chloride. Excipients: solid semisynthetic glycerides, hydroxypropylcellulose.

On the one vaginal tablet   accounting for 20 mg of benzalkonium chloride. Excipients: silicon dioxide hydrate, anhydrous citric acid, sodium bicarbonate, lactose, magnesium stearate, lactose.

On the one vaginal capsule   It accounts for 18.9 mg of benzalkonium chloride. Excipients: 7-glyceryl cocoate, polyoxyethylene, colloidal silica, hydroxypropyl cellulose, dimethicone, macrogol, gelatin, glycerol.

Per vaginal spermicide Pharmatex   accounts for 864 mg. (28.8 mg alone application) benzalkonium chloride. Other ingredients: macrogol, dehydrated citric acid, sodium phosphate dibasic dodecahydrate, essence of lavender oil, purified water.

Product form

  • Tampons are cylindrical in shape . Impregnated with an oily cream white with a lavender flavor. The package 2 pcs.
  • Candles in a plastic shell . The package of 10, 5 pcs.
  • Tablets round White color with a through hole in the center. The polypropylene tube 12 pcs.
  • Capsules oval   light yellow color. The blister pack 2, 6 pcs. In unit 1, 2 blisters.
  • The cream-gel in a tube . Volume 72 gr. Designed for 30 applications.

Pharmacological action

Benzalkonium chloride   It has a devastating effect on the membrane spermatozoal - spermicidal effect. Fertilization is impossible. Complete destruction of the spermatozoa is performed after 20 seconds after the interaction with contraceptive .


Additional antiseptic effect of using Farmateksa - antimicrobial activity against genital herpes . Staphylococcus aureus . trichomoniasis . gonorrhea . chlamydia . Against candidiasis   ( thrush ) gardnerellÑ‘za . Syphilis , Mycoplasma infection drug is virtually powerless.

It does not affect the hormonal cycle   and vaginal microflora.

Pharmacodynamics and pharmacokinetics

Vaginal mucosa does not absorb benzalkonium chloride. The absorption process occurs on the vaginal walls.

To remove the contraceptive quite natural physiological secretions and simple cleaning the water.

Indications

It is local contraception for any healthy woman of reproductive age.

  • before the onset of Menopause ;
  • if necessary in the prevention of episodic fertilization;
  • if misused oral contraceptives ;
  • with contraindications to the use of oral contraceptives species;
  • after abortion .

Contraindications

  • high sensitivity to chemical components of contraceptive local action;
  • diseases in the external genital organs;
  • irritable state of the vaginal mucosa.

Side effects

The components of the drug are not able to be absorbed into the blood and to the overall effect on the body as a whole, except for persons who have a severe sensitivity to benzalkonium chloride . In the case of Farmateksa in accordance with information specified in the instruction, the development of side effects are minimized, and typically in healthy women spermicides   do not exhibit any undesirable symptoms and side effects.

In the case of allergic reactions   (itching, burning, contact dermatitis ) Should be immediately excluded from the list of permitted contraceptive drugs for personal use.

Instructions on Pharmatex

All kinds of contraceptives Pharmatex taken vaginally in a horizontal position. Repeated sexual intercourse, use a new drug (a must!).

Guide to contraceptives candles : Candle taken for 5 minutes before intercourse. Activity is maintained for 4 hours, or until the first ingress of sperm into the vagina.

Instructions on vaginal tablets Tablets pre-moistened with water. After 10 minutes to be administered. Activity is maintained for 3 hours, or until the first ingress of sperm into the vagina.

Instructions for use cream Pharmatex : The gel is introduced by means of an applicator. Effective immediately. Contraceptive Cream assets are not more than 10 hours, or until the first contact with the sperm in the vagina. Those who do not know how many times enough cream, provided a reminder - one tube (72 g.) Is designed for 30 receptions.

Instructions for vaginal capsules : Candle is designed for deep feeding. Contraceptive spermicidal suppositories take effect within 10 minutes. Active for 4 hours, or until the first hit of semen into the vagina.

Instructions on vaginal tampons : Swab (sponge) introduced the efforts of his fingers. I should reach (touch) to the cervix. It operates up to 24 hours. After the act allowed the reuse of already inserted a tampon (up to three times). For the most light extraction swab to be taken position " squatting ".

Overdose

The low systemic absorption reduces the likelihood of an overdose to a minimum. By the current moment there are no signs of overdose described.

Drug Interactions

The intravaginal administration of a drug, as well as local effects hygiene products, Farmateks inactivated, i.e. spermicides lose their property. Allowed to use the drug with other oral contraceptives type.

Terms of sale

Pharmatex released on OTC basis.

Storage conditions

In a cool place at a temperature no higher than 25 C.

Shelf life

Pills . capsules : 2 years.

Cream . tampons . Candles : 3 years.

Analogs

Match code ATC 4th level:
  •  Pharmatex  Septefril
  •  Pharmatex  Benateks
  •  Pharmatex  NuvaRing

For contraceptive contains the following analogues: benateks, eroteks, kontrateks, farmagineks, spermateks .

Is it better or Benateks Pharmatex?

When considering the rough, both drugs are very similar, as the active ingredient at them the same. The differences in this case, primarily by the level of symptoms caused by, including excipients, which have somewhat different contraceptives.

Reviews farmateks

With regard to contraceptives have reviews of doctors Pharmatex - the drug is optimal contraceptive with many advantages: no side effects on the healthy organism, antiseptic and antimicrobial effect , Reliable protection against unwanted pregnancy. The same applies to the gel, a cream gynecologist reviews are positive.

Based on the comments of experts and users of the drug against Farmateksa, it does not matter that it is better, pills or suppositories, tampons or gel. As practice shows, backed by scientific research, Pharmatex tablet, gel, tampons, vaginal suppositories are equally good. In this regard, irrelevant to compare the effectiveness of Pharmatex candles, ointments, tablets, capsules, because the quality of the action at the same drugs.

Price Farmateksa

Pharmacies in Kiev (Ukraine) established the following price USD .:

  • Price pills 55 hryvnia. Non-hormonal birth control pills sold in a polypropylene tube in an amount of 12 pieces.
  • Cost candles Pharmatex 85 hryvnia or 50 depending on the amount in the container. Candles contraceptive sorted by 10 or 5 pieces. in a cardboard box.
  • Buy tampons   It will cost a total of more than 200 hryvnia.
  • Cream Ointment worth 85 hryvnia.
Get the best price and buy

Parlodel

Description overdue on 02/09/2013

Related Articles:
  • Renitek
  • Analgin during pregnancy
  • Instenon, instruction
  • Composition Kaffetina Kolda
Tweet

 Parlodel  Dopamine receptor agonists.   The drug suppresses physiological lactation It inhibits prolactin inhibits hypersecretion of growth hormone promotes the stabilization of the menstrual cycle, reduces the number of cysts in the mammary gland and their sizes (due to restore the balance between the level of estrogens and progesterone). The drug stimulates the central and peripheral D2-dopamine receptors.

The active substance is an ergot alkaloid derivative. Large quantities of the medication is able to stimulate the receptors black nucleus and the striatum of the brain, the hypothalamus and mesolimbic system. The main ingredient in the drug Parlodel - bromocriptine . The drug is able to inhibit the hormone ACTH and growth hormone. Bromocriptine has antiparkinsonian effects . Receiving unit dosage rate decreases prolactin 2 hours, the maximum therapeutic effect is observed after 8 hours. Reduced levels of growth hormone occurs after 1-2 hours, the maximum effect is recorded after 4-8 weeks of therapy. Antiparkinsonian effect observed after 30-90 minutes, and the maximum - in 2 hours after administration of a single dose. Parlodel available in tablet dosage form.

Indications:

Instructions for use of the drug Parlodel recommends that prescribers in the menstrual cycle, female infertility: prolaktinzavisimye conditions and diseases that are accompanied or not accompanied by giperplolaktinemiey (luteal phase deficiency, oligomenorrhea, amenorrhea, hyperprolactinemia secondary to the background of antihypertensive drug therapy and psychoactive drugs). The drug is prescribed for premenstrual syndrome, manifested by swelling, breast tenderness, mood lability, increased flatulence. The drug is indicated for use in the prolaktinnezavisimom female infertility: the anovulatory cycles (in the complex therapy in conjunction with antiestragenami) in polycystic ovary syndrome.


Persons male Parlodel prescribed for prolaktinzavisimom hypogonadism (loss of libido, oligospermia, impotence). The drug is prescribed for prolactinoma: conservative therapy of pituitary microadenomas and macroadenomas, prolactin-secreting. Bromocriptine may be appointed before surgical treatment to reduce the size of the tumor and facilitate its lysis. The drug is used in an increased level of prolactin in the postoperative period. Acromegaly Parlodel used as further medicament in combination therapy in conjunction with surgical treatment or radiation therapy, and in some cases as an alternative radiation therapy and surgery.

The drug is prescribed to suppress lactation for medical reasons (for developing postpartum mastitis, to prevent lactation after an abortion at the postpartum breast engorgement). The drug is used in fibrocystic breast, cystic and nodular changes in the breast benign nature, with mastalgia. In Parkinson's disease Parlodel can be assigned to all stages of idiopathic disease in postencephalitic parkinsonism (monotherapy or combination therapy together with other antiparkinsonian drugs).

Contraindications:

Parlodel does not apply to endogenous psychosis , Chorea Gettingtona at family tremor, bromocriptine intolerance - the main substance of the drug, with hypertension in the postpartum stage, hypotension, ulcerative lesions of the digestive tract, essential tremor , Gestosis, arterial hypertension, diseases of the cardiovascular system. Simultaneous treatment of antihypertensive drugs, with gestation pregnancy, with symptoms of parkinsonism dementia   the drug is prescribed with caution. The active substance is excreted in milk during lactation, which limits the use of medication during breastfeeding.

Side effect:

Occasionally during treatment with bromocriptine developed orthostatic hypotension , Dizziness, vomiting and nausea. There are headaches, disturbances of vision, stroke, hypersomnia, psychomotor agitation, psychosis, hallucinations, constipation, myocardial infarction, psychomotor agitation , Dry mouth (orokandidoz, caries Discomfort, periodontal disease), skin rash, cramps in the calf muscles, allergic reactions, nasal congestion. Long-term therapy can bring to the development of Raynaud's syndrome.

In the treatment of Parkinson's disease with high doses of the drug may fainting , Bleeding from the digestive tract (in the form of black stool, and the appearance of blood in the vomit) peptic ulcer , The allocation of cerebrospinal fluid from the nose, confusion, retroperitoneal fibrosis   (frequent urination, nausea, back pain, loss of appetite, abdominal pain, vomiting, weakness in the whole body).

Overdose:

Manifested headaches, a fall in blood pressure. It is necessary to parenteral administration of the drug metoclopramide.

Mode of application:

Parlodel Inside, during a meal. At day - 100 mg. When female infertility, menstrual irregularities   bromocriptine taken three times a day for 1, 25 mg. In case of failure of the daily amount of medication may be increased to 5, -7, 5 mg. Therapy is conducted to restore ovulation, the stabilization of the menstrual cycle. Treatment involves several cycles, if necessary, prevent a recurrence. When hyperprolactinemia in males:   three times a day for 1, 25 mg 2-3 times a day with gradual increase in the daily dose of 5-10 mg. When premenstrual syndrome: on the 14th day of the menstrual cycle administered 1 25 mg per day, the amount of drug increased gradually to 5 mg per day (every day 1, 25 mg) to the onset of menstruation.

When prolaktinoma   administered 2-3 times a day for 1, 25 mg, DAILY amount of drug can be increased by the need to stabilize certain level of prolactin in blood. The initial dose is 1 acromegaly, 25 mg 2-3 times a day, further treatment strategy depends on the severity of side-effects and the clinical effectiveness of the medicament. For suppression of lactation   administered on the first day 1, 25 mg bromocriptine twice daily for 2 more weeks - 2, 5 mg twice a day. The drug is recommended to take immediately after birth to prevent the start of lactation (after stabilization of the mothers). Possible slight secretion of milk in 2-3 days after discontinuation of therapy. In this case, treatment is extended for one week at the same doses.

When postpartum breast engorgement   the drug is prescribed in a dose of 2, 5 mg dose, repeated reception is possible in 6-12 hours (does not cause an undesirable suppression of lactation). When developing postpartum mastitis   similar to the treatment regimen of therapy to suppress lactation. You can add to the antibiotic regimen. When benign breast Parlodel take 2-3 times a day 1, 25 mg of the drug daily amount gradually increased to 5-7, 5 mg.

In Parkinson's disease   treatment is initiated with minimal doses 1, 25 mg for optimum portability. Weekly, daily quantity of the medicament is increased by 1, 25 mg. The therapeutic effect is seen after 6-8 weeks of therapy. Otherwise weekly dose escalation continues. When side effects on the background of the selection and increase the dosage amount of the drug is reduced by 1 week. After stabilization of the titration continue. Patients with movement disorders caused by levodopa before drug treatment Perlodel lower dose of levodopa. In some cases, achieved a complete removal of the drug L-dopa.

Special instructions:

It requires regular monitoring of renal function, hepatic system, the level of blood pressure. For the prevention of vomiting, nausea before treatment is prescribed antiemetic medications. The drug affects the control of a motor vehicle and perform activities that require attention. Against the background of treatment with Parlodel may prompt restoration of ovaries after birth, which requires the use of contraceptives for the prevention of early conception.

Patients who take medication, pregnancy occurs when therapy is stopped except when the effect of the drug outweigh the potential risk to the fetus. During treatment, non-hormonal contraception is recommended that bromocriptine. In the event of pregnancy, a pituitary adenoma, after the cessation of treatment requires the study of the visual fields, the systematic observation of the adenoma. Responses to the drug Parlodel demonstrate high efficiency of medication in compliance with all medical prescriptions.

Before the treatment of benign tumors of the mammary glands necessarily exclude malignant nature of the tumor. If a peptic ulcer of the digestive tract bromocriptine therapy is not indicated. It is necessary to inform patients about the necessity of seeking medical help with the appearance of side effects from the digestive tract. It requires careful oral hygiene during treatment. Buy Parlodel drug can be in the pharmacy network upon presentation of a medical prescription form.

Drug Interactions:

Parlodel is able to reduce the effectiveness of oral contraceptives.   Clarithromycin, erythromycin and troleandomycin can increase the maximum concentration and bioavailability of the drug; butirofenov application leads to the opposite effect. Furazolidone, MAO inhibitors, selegiline, procarbazine, loxapine, haloperidol, ergot alkaloids, metoclopramide, methyldopa, reserpine, fenotiazidy, thioxanthine increase the risk of side effects by increasing the concentration of active substance in the blood plasma.

Parlodel increases the effect of antihypertensive agents, levodopa. Development disulfiramopodobnyh reactions   observed while taking ethanol (appears cough reflex tachycardia, flushing of the skin, chest pain, vomiting, nausea, convulsions, disturbances of vision, throbbing headache). If necessary, treatment with Ritonavir is necessary to reduce the daily dose of 2 times.

Lasix

Description overdue on 14.12.2011

Related Articles:
  • Normoven
  • Price Vitrum
  • Reviews for syrup for children Depakine
  • Tablets Pikolaks
Tweet

 Lasix  The active ingredient of the drug Lasix   It is Furosemide . It has a diuretic action of producing reuptake blockade of sodium ion and chlorine loop of Henle   (in its rising part). Lasix also significantly affects the convoluted tubules. It accelerates the excretion of magnesium, potassium, calcium. When administered by intravenous Lasix rapidly decreases blood pressure, pulmonary artery pressure and the left ventricle. Within five minutes after injection into a vein can be seen diuretic effects, the maximum effects of drugs observed in thirty minutes. The diuretic period lasts about two hours. For internal use of its diuretic effect of the drug begins within the first hour, and two hours later it reached the maximum level. The effect after receiving the last about seven hours. Lasix excreted in the urine as the compound with glucuronic acid .

Indications and methods of use of the drug:

Lasix drug prescribed to patients who are diagnosed edematous syndrome That evolved as a result of the following diseases: heart disease, kidney, liver, acute left ventricular failure, burn disease, preeclampsia pregnant women (in this case, Lasix is ​​used only after the restoration of the BCC). The drug is also used in the process of forced diuresis   and during the complex therapy of hypertension.


The dosage and method of use of the drugs administered individually. The dose is adjusted depending on the severity of disease and the amount of urine output. Typically, the drug is taken in tablets, but urgent cases, it is administered by intravenous bolus, during 1.5-2 minutes.

If edema syndrome have an average degree of severity, the drug is prescribed in a dose of 20-80 mg (oral) or 20-40 mg (reception intramuscularly or intravenously). If the sufficient effect is not observed, the dose is increased by 40 mg (oral) or 20 mg (injection). The dose is adjusted until adequate urine output. The greatest effect of the drug is observed in the case where it is assigned 2-4 times a week.

Before the drug dose is calculated children given the child's weight and method of administration. If conducted oral, the starting dose is 2 mg / kg if receiving an injection, it is administered 1 mg / kg. Further the dose can be increased to 2 mg / kg (oral) and 1 mg / kg (injection).

In the treatment of hypertension using 80 mg of the drug knocks. This dose should be divided into two steps. If the effect of the treatment is not observed, then there is no need to increase the dose. It is parallel to taking other antihypertensive agents.

In the case of pulmonary edema 40 mg of Lasix administered intravenously. If there is no effect, after 20 minutes, introduced another 20-40 mg. When forced diuresis, 20-40 mg of Lasix is ​​added to the solution for infusion. Further, the dose may be adjusted.

Contraindications and side effects:

Do not take Lasix at electrolyte imbalance, severe intolerance to furosemide or other components of the drug, with the anurii . dehydration . deficit bcc . hepatic coma . Also, the drug is not administered during the first trimester of pregnancy and during breastfeeding.

As side effects can be observed decrease in blood volume (for large doses of drug), therefore, can manifest hemoconcentration and thrombosis . Often when taking Lasix develop water-electrolyte disturbances: alkalosis , Lack of chlorine, sodium, calcium, potassium, as well as violation of the biochemical characteristics of the blood.

May develop allergic reactions: skin manifestations, in some cases - anaphylactic shock . Rarely can occur leukopenia . thrombocytopenia , Hemolytic changes eosinophilia . agranulocytosis . When pregnancy (second and third trimester) Lasix can be used only in case of strict indications.

Specific recommendations:

Lvaziks may enhance the effects of cardiac glycosides . Could improve antibiotics   blood while taking Lasix and cephalosporin antibiotics or aminoglycosides . In parallel reception ACEI   Lasix and can significantly increase the hypotensive effect leading to collapse and reduce the development of kidney function.

In parallel consumption of alcohol can reduce the concentration of attention and speed of reaction. In case of overdose there may be a manifestation hypotension , Electrolyte imbalance, dry mouth, dizziness, vision problems. Store this medication Lasix must be in a dark place, with temperature control should be between 17 to 26 ° C.

Friday, May 25, 2018

Postpartum psychiatric disorders: psychosis, depression

June 24, 2012

Related Articles:
  • Causes Panic Attacks
  • Late childbirth protects against oncological diseases
  • Instructions on Femoden
  • Paranoia
Tweet

 Postpartum psychiatric disorders: psychosis, depression  Postpartum psychosis   and postpartum depression   - It states that occur in women as a consequence of complications arising during delivery . It is crucial that new mothers diagnosed with postpartum psychosis, be sure to seek the help of a qualified and receive appropriate treatment.

This should be taken into account due to the fact that most new mothers are not even aware that they are already suffering from the symptoms of postpartum psychosis. Sometimes these symptoms are not perceived as a serious disease, and people close to the woman.

It is to share the concept of "postpartum psychosis" and "postpartum depression." Both of these diseases are very severe psychotic condition that requires immediate medical treatment. But the approach to the therapy of these diseases apply different: the treatment of postpartum depression goes with Antidepressants And treatment of postpartum psychosis is carried out using antipsychotics . Compared with symptoms of postpartum depression postpartum psychosis occurs less frequently in women. It is necessary to clearly distinguish postpartum psychosis and postpartum blues, which the majority of young mothers occurs in the first weeks after birth. In most cases, this takes the blues yourself. However, it happens that the prolonged blues goes into post-natal depression. Such a condition should be treated with the help of qualified professionals.

Causes of postpartum psychosis

Postpartum psychosis is a severe psychotic condition. During pregnancy   a woman who later suffers from postpartum psychosis, no noticeable abnormalities. However, those who are prone to psychosis in the postpartum period, usually before suffering from severe emotional vibrations during premenstrually


To date there is no information on the precise causes of manifestations of this condition in women after childbirth. There are some suggestions for changes in the psyche of women, recently given birth a child associated with fluctuations hormonal balance   in her body.

The high risk of developing postpartum psychosis exists in women who have a history of a variety of mental illnesses and disorders. For example, postpartum psychosis are more prone to young mothers with schizophrenia and bipolar disorder. Significantly increases the risk of postpartum psychosis in those who previously abused a variety of drugs.

However, postpartum psychosis can develop in healthy women who have experienced severe emotional stress due to the birth of the baby.

Symptoms of postpartum psychosis

 Postpartum psychiatric disorders: psychosis, depression  Typically, postpartum psychosis, manifested for 3-6 days after birth. At the characteristic features of postpartum psychosis often we are talking about the loss of communications with the reality of the patient. With the progression of postpartum psychosis is disturbed higher nervous activity. In women immediately after the birth is shown as easy And heavy   form of postpartum psychosis. If it is for a particularly heavy, the young mother can completely lose the ability to care for a newborn.

In the development of postpartum psychosis can manifest a number of different symptoms. The woman sometimes observed some manic symptoms, which are expressed in high levels of arousal, the occurrence of obsessions, which are not connected with reality.

Another very common manifestation of postpartum psychosis in women are hallucinations, especially hearing. The young mother gradually develop personality changes, her thinking becomes abnormal. Postpartum psychosis-prone woman becomes difficult to articulate their thoughts and organize them aloud. Accordingly, a woman can lead rambling conversations, to express thoughts without intelligible content.

The patient can not give an adequate self-esteem, the right to define their own state. Convincing young mother that she should seek qualified help, her family and relatives should make substantial efforts to achieve the desired. Eventually, after a full cure, the woman usually realizes the error of their beliefs.

Another symptom of postpartum psychosis is a disorder of appetite: the young mother often can not eat normally.

A woman in a state of severe postpartum psychosis is often visited by the idea of ​​a possible suicide or murder. This symptom shows that the patient's condition is extremely serious, and she needs the help of experts.

Diagnosis of postpartum psychosis

When you call a woman to the doctor with complaints of the above symptoms the doctor should spend as much as possible a full examination of her state of health. Identification of organic diseases, blood tests and other studies help explain the causes of post-partum psychosis. You also need to bring a neurological examination, as well as examine the results of a CT scan.

Treatment of postpartum psychosis

 Postpartum psychiatric disorders: psychosis, depression  Treatment of postpartum psychosis has been practiced for a long time. Currently used as oral and intravenous and intramuscular administration. But all drugs should be used as soon as possible, as treatment for postpartum psychosis should be made as early as possible. From this it depends on the success of this therapy. Accordingly, the effectiveness of treatment may decrease if you start it later.

If urgent medical intervention does not happen, then the state of postpartum psychosis, a woman could rapidly deteriorate. This directly threatens the health of mother and child.

Postpartum Depression

Postpartum depression can occur in every woman who gave birth to a child recently. This condition is also seen in women who have given birth to a stillborn child after a miscarriage. Postpartum depression is manifested by changes in the psychological state of the woman. It may suffer from permanent display feelings of sadness, pessimism, hopelessness. Young mother ceases to feel the joy of life, the pleasure of caring for a child. Sometimes young mother feels that it is too hard to show the daily care of the baby. To date, there is evidence that the prevalence of symptoms of postpartum depression is up to 15%. It is important to take into account the fact that postpartum depression in the mother can affect the baby's health in the future.

If you evaluate the status of the young mother immediately after birth, the state of tiredness, weakness and exhaustion there is almost every woman. In the first few weeks after birth the young mother can suffer from insomnia, weakness. All of these feelings in the majority of young mothers occur in parallel with the state of joy and great satisfaction from the fact that the child was born. But if a woman has a normal state after a few weeks of feeling that her condition becomes more stable and unpleasant symptoms disappear without treatment.

Causes of postpartum depression

It is believed that the cause of postpartum depression is a manifestation of a sharp hormonal imbalance in women, which is manifested immediately after birth of the baby. In the development of pregnancy in a woman's body undergoes substantial change psychological . somatic   and endocrine   character. Mental dysfunction in the period after childbirth, according to doctors, is associated with a sharp decrease in the number of body HCG at .

But while there are some factors that provoke an increased risk of symptoms of postpartum depression. First of all, it is important to consider that postpartum depression often seen in women who had previously been at the birth of children suffering from this disease. Very often postpartum depression occurs in this group of women at the birth of a child after 35 years. However, there is evidence and that postpartum depression much more often seen in women at the birth of first child.

In addition, significantly increases the risk of manifestation of the lack of adequate state support for young mothers, which should ensure that relatives and close friends. Postpartum depression is more common in women who have had a strong stress . It can trigger health problems in the newborn, regular colicky baby, the presence of other family or psychological problems.

If a woman was likely to be depressed in the period of gestation of the child, 75% of depression manifested in her and after childbirth. Also increases the chances of symptoms of depression hereditary predisposition to the young mother   depressive states   either bipolar disorder .

Symptoms of postpartum depression

 Postpartum psychiatric disorders: psychosis, depression  Since the birth of a child is a serious stress for the woman, the development of depression in the postpartum period occurs often enough.

The most common symptom of postpartum depression is a denial of a young mother with the necessary skills. A woman who had just given birth to a child, feels that it is very difficult to cope with new responsibilities, and at the same time feels a sense of guilt. Woman suffering from severe anxiety, while it becomes very slow and with great difficulty focusing. Sometimes a woman completely reject all social contacts and fully immersed in the cares of the child. In other cases, postpartum depression causes the mother to opt out of care for the child. Most postpartum depression becomes chronic and long-term negative impact on the child and the mother.

Very often a young mother suffers because it does not receive confirmation of the theory that her maternal instincts will help to transfer all the difficulties of the adaptation period to the child quickly. But in fact, for such a bond between the mother and the baby appeared and gained strength, you need a few months. Hence, the disappointment of failure could trigger a worsening of depressive state. Besides, very often the mother is convinced that the child is responsible for it alone.

Thus, a sense of sadness, spiritual emptiness and constant anxiety can pursue a woman for a long time. Gradually she loses the ability to enjoy everyday amenities. The symptoms of postpartum depression are also often a loss of appetite, rapid weight loss in young mothers. Women can also suffer from insomnia.

The above symptoms may be a woman in the first week after birth, and after a few turbulent weeks. Postpartum depression can last from a young mother about three or four months.

Types of postpartum depression

In medical practice, accepted definition of the classification of postpartum depression. At neurotic depression   a woman has exacerbated those disorders that took place in the period of pregnancy. It is in a depression, often cries, and gradually comes to an extreme degree of burnout.

Traumatic neurosis Usually manifests itself after a very severe birth process. Women who have experienced a difficult birth, before the next birth of the child gradually increases anxiety, obsessive fears.

At melancholia, accompanied by delusional inclusions For the condition of the woman is characterized by severe confusion, guilt, and thoughts of their own inadequacy. A woman can not learn those close to her, suffer from a permanent manifestation of unpleasant hallucinations. Very often this state precedes the manifestation manic-depressive psychosis .

When postpartum depression with neurotic component of a woman's symptoms may hypochondriacal nature, as well as insomnia, and a manifestation of the feeling of powerlessness. Mother constantly afraid of something to hurt your child.

The most commonly found in young mothers for postpartum depression is prolonged. At the same time a similar condition often occurs in women are not diagnosed, although they suffer approximately 20% of new mothers. As a symptom of this condition there is a constant feeling of fatigue, sadness, exhaustion. Mother is very difficult to carry the crying child, she becomes irritable, and constantly feel guilty for such behavior.

Diagnosing Postpartum Depression

Diagnosis of postpartum mental disorders is carried out by a medical examination, as well as a detailed survey of the patient. It is imperative that a woman as detailed as possible to tell the doctor about your own feelings, thoughts and emotions that dominated her after birth. During the treatment the doctor is required to watching the patient and watching her psychological state. It is important that there has been a careful attention to the complaints of a woman doctor, because mental disorders are sometimes overlooked.

Treatment for postpartum depression

 Postpartum psychiatric disorders: psychosis, depression  Treatment for postpartum depression and postpartum psychosis involves mandatory consultation of psychologist and receiving medication. When postpartum depression woman prescribe drugs-antidepressants . But if the patient holds moderate postpartum depression, that without medication, in some cases you can do. To date, the use of modern antidepressant drugs allows us not to give up breast-feeding, as they do not adversely affect the baby. But it is important that the funds assigned exclusively to professionals.

However, the treatment of postpartum depression also involves proper nutrition, physical activity, a sufficient number of hours of daily sleep. In addition, women need to realize the incorrectness of their own behavior and be sure to ask for help from their loved ones.

Prevention of postpartum mental disorders

It is understood that on the prevention of postpartum depression and postpartum psychosis need to take care of long before the appearance of the child. Expectant mother should always be in a comfortable environment to feel concern and support. It is particularly important to ensure similar conditions for women who have an increased risk of symptoms of mental disorders. In this case, it is extremely important attitude towards women of her partner.

Both husband and wife before the birth should understand that the risk of developing postpartum depression exists in every woman, so this is important to recognize the condition and to ensure its adequate treatment.