I do not want to live with pain

Those suffering from this disease can sometimes under the influence of pain self-harm, even kill himself. The saddest thing - the disease often mistaken for ordinary toothache. And all because of trigeminal neuralgia (trigeminal neuralgia - HS) covers the lower part of the face and jaw.

In Russia, the official from the disease affects about 30 thousand people, unofficially - is much greater. Unfortunately, doctors do not always give the correct diagnosis. Monstrous in terms of suffering twinges of accidents suddenly attacked, they can last for seconds, minutes and sometimes hours.

"The pain is just unbearable - says neurologist Anish Bar of the National Hospital for Neurology and Neurosurgery in London. - My patients say that they seemed to be cut to pieces saw. In a fit of agony they tremble in convulsions. And after the acute phase is a dull ache that can persist hours or even days. "

Nine out of ten cases trigeminal neuralgia   pressure caused by blood vessels on the trigeminal nerve. But the immediate cause of the next attack could be anything - a draft, the food, drinks, shaving and even brushing teeth. "There were cases when the pain turn gave rise to the head or a light touch to the face - says Dr. Bar. - This disease affects patients of all ages, but most of its victims are people over 50".

Special tests designed to diagnose   trigeminal neuralgia , does not exist. However, the disease can be detected using MRI and angiogram (radiograph obtained after angiography). In more than two-thirds of effective medicines against trigeminal neuralgia   are anticonvulsants (medications anticonvulsant action) that block the transmission of nerve signals. In the remaining third of the cases the patient can save rhizotomy surgery - transection of the cranial nerve roots. Effective treatment is also microvascular decompression, during which there is a division of the nerve roots and blood vessels.

Treatment and prevention

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Transcribed gene migraine

The scientists were able to identify "gene migraine." This discovery gives hope to many patients suffering from painful headaches.

Migraine is one of the most prevalent diseases in the world. Painful migraine attacks It affects every eight people. Intense headaches may be accompanied by nausea, blurred vision, increased sensitivity to bright light. An attack can last up to three days and negatively affect the well-being of people.

Drugs to fight migraine,   developed to date are not always valid and can help not for everyone. Some of them have, in addition, side effects. But now for the sick migraine there is hope for a cure.

An international research team, led by experts from the Wellcome Trust Sanger Institute in Cambridge, compared the DNA of thousands of people suffering from   migraine DNA people without such a problem. As a result, we were able to identify a gene "responsible" for the painful attacks. Scientists hope that this discovery will help to develop new approaches in the treatment of migraine, to create an effective drug that can save people from an intense headache.

Industry News

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To create the best in the history of a vaccine against malaria

American scientists reported a major breakthrough in the prevention of malaria in recent history. To create a vaccine that provides maximum protection of the human from this dangerous disease.

a vaccine against malaria

In Russia and other developed countries, malaria is considered something exotic, but in the poorest countries of the Third World is the main cause of mortality. Malaria is dying more people than heart disease, cancer or other ailments. And this disease is not age, it is with the same force and kills the young and the elderly. That is why the science of this energy is working on a vaccine against malaria, the world's richest man Bill Gates has donated to the research more than a billion dollars.

a vaccine against malaria

Apparently, the money is still given result. US scientists have created vaccine against malaria   called PfSPZ. In clinical trials, 100% of people who received a higher dose of medication, do not get sick with malaria. Just experiments attended by 57 volunteers, 40 of whom received injections in different doses.

A vaccine against malaria   PfSPZ made on the basis of the malaria parasite Plasmodium falciparum, is in the infectious stage, that is contagious. To study these parasites have been weakened by radiation, and then frozen. However, they kept their whole form and can infect humans. The volunteers were bitten by parasites, and within a week they were to show signs of the disease.

Get full intravenous PfSPZ volunteers were completely protected - no one has developed malaria. Those who got the lower dose of 9 people were infected with 3 out of 12 do not immunized malaria occurred in 11. All patients received timely treatment of malaria and recovered. About any side effects of the vaccine is not known. (READ MORE)

Industry News

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Facelift by using strings (stranded lifting)

April 8, 2013

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Filament lifting (also called the procedure stranded tightening ) Recently gaining relevance. This procedure draws those who need a face lift, especially pronounced effect that persists for a long time. In addition, this tightening has little contraindications, and rehabilitation after the conference lasts a relatively short time. At the same time the patient retains the natural features, and the visible incisions and scars are left.

Types facelift

That person is able to inform others about the true age. The person - an open area of ​​the human body, and it primarily affects the sun and wind, and a variety of beauty treatments. Therefore, the skin on the face with age becomes less elastic, wrinkles and facial muscles lose their tone. Unfortunately, to remove age-related changes by using cosmetics is impossible. But plastic surgery can significantly improve the situation. Facelift - precisely the procedure that can significantly improve the appearance and get rid of the problems. Most often lift facial contours required for women of mature and elderly.

Before you find out how much is this procedure and what are the prices for different types of plastic face, a woman should consult with a plastic surgeon. He individually assess the situation and will advise which of the treatments will be most effective.

A non-surgical facelift   - A great alternative to surgery. Such lifting, of course, does not resolve much sagging tissue, however, it provides an opportunity not only to get rid of wrinkles, but also to align the shape of the face. Non-surgical lift is often performed in the event that a woman needs to adjust certain parts of the face.

Facelifting   It gives a more drastic results. With it, you can greatly improve the contours of the face to get rid of double chin, much saggy cheeks. The final result after such an operation can be seen in about six months.

Endoscopic Face Lift   is performed using a special endoscopic techniques. After such an operation, the skin incisions are very small (less than 3 cm). The rehabilitation period it is very short, as low-impact intervention. Endoscopic facelift can be used, if required correction of certain areas of the face. Very often it is practiced to lift the upper part of the face. To determine the usefulness of such an intervention is, and call it the final cost of the doctor may only after a personal consultation.

Laser Facelift   It is carried out using laser radiation, which stimulates the process of rejuvenation. Reviews of such procedures indicate that their effect gives good results. Activates metabolic processes, new collagen fibers, improves blood circulation. Because such processes oval face appreciably aligned, and wrinkles disappear. Therefore, this method is often practiced as an alternative to surgery.

Facelift threads

Facelift threads   It is relatively gentle procedure and achieves visible results. Its growing popularity, as well as positive comments from those who have already tried this procedure, make it possible to draw a conclusion about the effectiveness of this type of lift.

In the course of this procedure special absorbable sutures for a facelift. This relatively sparing procedure involves placing a person under the skin of special biocompatible filaments. These yarns allow to move the fabric and to fix them in position. During the tightening using filaments not need large incisions, therefore, patients are recovered rapidly. At the same time the result is so well marked that even impressive photo viewing "before and after".

This procedure is often carried out by women aged 30 to 40 years. However, the lift can be carried out in the presence of the first signs of aging in humans. There are several types of braces threads. The most popular options - lift Aptos threads and golden threads, which is primarily a manufacturer of Korea.

Types stranded lift

The principle effects of different types of lifting the filament is different. If necessary, a light facelift preferred lift Aptos threads . The effect of this procedure is maintained for about two years. Therefore, it is necessary to choose those who have lost facial contour slightly. Such yarns are thin, they are made of polypropylene, have a notch in a "herringbone pattern", which allows to displace the skin for subsequent fixing it in position. A doctor with a special fine needle injects them into the soft tissues of the face and captures the desired location of the facial points. Consequently, the fabric moves to a new position.

To place the threads in the fabric of the person makes a small incision - no more than 3 mm. Facelift without surgery Aptos thread passes with local anesthesia . The whole procedure takes less than half an hour. Immediately after manipulation completed, the patient can see a certain result. After 2-3 weeks, you can talk about the final result and hear patient testimonials about the effect of such a procedure. During this time, it is important to avoid a very active facial expressions, as well as chewing movements. The effect produced by this lift is maintained between 2 and 3 years. Its cost depends on a number of specific features. Therefore, it is important to consult an experienced doctor, who concluded whether you need a circular face lift, or you can do gentle option. To submit a more detailed process and result, wishing to make such a lift can view photos and videos. Aptos Threads for face-lift has been used for about 10 years, which suggests that the high efficiency of the procedures and safety of the method.

Lift with gold thread   - More gentle version of this procedure. It is performed on an outpatient basis. In general, the procedure takes no more than one hour. According to experts, this method of rejuvenation is more like injection methods than the classic facelift.

Under the skin of the patient entered a very thin thread of gold the highest standard. In response to the introduction of a foreign body in the body defense reaction triggered. Activated development Collagen   and elastin And the blood flow near the implanted tissue. As a consequence, the skin get essential nutrients, whereby lifting occurs effect.

Evaluate the result after such a procedure can be no earlier than 3-4 months. 5-10 years, it is stored, but it will affect the individual characteristics of the patient.

Relatively recently begun to use a facelift thread Silhouette Lift . This procedure is similar to tightening the threads Aptos. Threads Silhouette Lift is also made of polypropylene, however, as the clips here are special microcones. After the braces are cones dissipate with time. They are replaced by connective tissue, so the effect of this procedure is maintained for a longer time. Manipulation takes about 45 minutes. The patient is doing a local or general anesthesia and through an incision in the scalp is introduced thread and fix them under the skin. Following the lifting of its results can be stored up to 6 years. Later, you can not repeat the manipulation and tighten the set yarn.

Currently, facelift also apply 3D Mezoniti Made from polylactic acid. In this case, not only achieved lifting effect, but also the patient may experience the effect of simultaneously mesotherapy .

Indications

Experts beauticians provide a range of indications for patient lifting the filament. This procedure is advisable to carry out those with marked manifestations of gravitational ptosis. This appearance on the face of the nasolabial folds, flews, the omission of the corners of the lips and eyebrows. Filament lift is recommended also at age flattening face the first signs of aging, while the need to strengthen the result after non-surgical procedures other facelift.

Contraindications

It identifies a number of absolute contraindications for Lifting the filament . It is the presence of autoimmune diseases and cancer, bleeding disorders, allergic reactions in severe form, a number of chronic diseases of the skin (in this case, professional judgment).

There are also some relative contraindications. Such are pregnant, breastfeeding, the presence of inflammation in those places where it is necessary to introduce the thread fevers.

Rehabilitation

A very important period is the time after the procedure when there is a process of rehabilitation of the body. All the recommendations that the patient will hear from a specialist, rather simple. The most difficult thing is the feeling of psychological discomfort that lasts up to five days. In the first days after the lifting of the filament on the face may appear swelling, hematoma. Sometimes the skin is a little drawn.

The swelling subside by about the third day after the procedure. Two weeks later, they disappear completely. In general, the period of rehabilitation lasts about 1 month. In the first week after the surgery the person is recommended to sleep only on their backs. You also need to give up the trip to the sauna, swimming pool, sauna. Massage and other beauty treatments a person can do in a month after lifting the filament.

Doctors recommend that even before the procedure to give up smoking and to try to get rid of overweight . Then, the recovery period is much easier to pass.

Cere

Description overdue on 08/12/2014

• Latin name: Cerebrolysin
• ATC code: N06BX
• Active substance: Cere (Cerebrolysin)
• Manufacturer: EVER Neuro Pharma GmbH, Austria

Photos of the drug

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Cere
• Contraindications
• Side effects
• Injections Cere: instructions for use
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• For children
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The structure consists of one milliliter of solution 215, 2 mg concentrate Cere   (peptide drug, derived from porcine brain) and auxiliary components: Caustic Soda (Natrii hydroxidum), water for injection (Aqua pro injectionibus).

Product form

The drug is available in the form of injection with a 5% concentration. The drug enters the pharmacy apmulah   (5 mL Cerebrolysin №5; №10 1 ml; 2 ml №10; №5 10 mL) and sealed with a rubber stopper coated with fluoropolymer volumetric brown glass bottles of 30 or 50 ml.

Please be aware that Cere tablets are not produced .

Pharmacological action

The drug is stimulator neurometabolic processes   (nootropic effect).

Deproteined hydrolyzate pig brain substance stimulates cell differentiation, improves the functional state cells of the nervous system   and activates the mechanisms for the protection and renewal.

Conducted animal experiments have shown that contained in Cerebrolysin biologically active amino acids   and Peptides   have a direct effect on neuronal plasticity of synaptic and that in turn helps to improve higher brain functions .

Pharmacodynamics and pharmacokinetics

The studies using models of cerebral ischemia brain was found that the use of the drug allows:

• reduce heart attack ;
• prevent edema ;
• stabilized microcirculation;
• normalize cognitive and neurological disorders ;
• double the survival rates.

Based on studies using models Alzheimer   led to the following conclusion: in addition to the fact that the drug has a direct effect on Neurons It also increases the number of molecules transports glucose across BBB   (blood-brain barrier), and consequently compensates for critical energy deficit in the organism.

Quantitative analysis encephalograms healthy people and patients diagnosed vascular dementia It showed that treatment with the drug Cere:

• significantly increased neuronal activity   (indicators of activity are dose-dependent);
• objectively improved higher brain functions ;
• increased capacity for self-care and daily tasks (as a consequence - to a lesser extent a patient in need of constant care);

The drug has neurotrophic activity That can significantly slow down, and in some cases stop progression of neurodegenerative processes .

During the experiments, it was revealed that Cerebrolysin not provoke the formation of antibodies or the development of anaphylactic reactions, does not affect the immune system Not stimulated histamine receptors   and it has no effect on hemagglutination of erythrocytes .

As derived from porcine brain proteolytic peptide fraction includes short biologically active peptides Similar or identical to those produced in the body, an accurate drug pharmacokinetic analysis is not possible.

Based on the data of pharmacodynamic drug it was concluded that after single administration neurotrophic activity hydrolyzate plasma   determined over 24 hours.

Cere components have the ability to penetrate through BBB . Preclinical in vivo studies have established an identical effect of the drug on farmakodinamichekoe CNS   when administered in brain ventricles   and upon peripheral administration. These studies are an indirect confirmation of the ability to pass through Cere the cell membranes of the BBB .

Indications Cere

Indications for use Cere are:

• organic lesions, metabolic disorders and degenerative diseases of the National Assembly (in particular disease Altsegeymera );
• Complications developed on the background of suffering stroke ;
• brain injuries and their consequences (the state after neurosurgical operations transferred concussion   and closed head injury);
• mental retardation in children;
• mental disorders Which are accompanied by memory impairment, distraction, etc ..

Contraindications

The drug is contraindicated in case of hypersensitivity to its components, patients suffering from seizures At severe renal impairment .

Side effects

In rare cases, injections may provoke Cere:

• loss of appetite;
• depression;
• apathy;
• general weakness;
• arterial hypo- or hypertension;
• hyperventilation syndrome;
• the appearance of shortness of breath;
• chest pain;
• fatigue;
• the appearance of flu-like symptoms.

Sometimes, the therapeutic effect may be accompanied by agitation - A strong emotional arousal with aggression, confused mind, insomnia.

Too rapid administration of the drug may cause disorders of the nervous system, skin and subcutaneous tissue disorders: dizziness , Appearance tremor . sleepiness .   headache , Feel heat , Increased sweating, itching   and redness of the skin, skin rash (including including the appearance maculopapular rash ) hives .

In a few cases were noted:

• giperchuvstitelnosti reactions or allergic reactions, angioedema . anaphylactic shock , Chills and fever ;
• Generalized seizures ;
• increase in seizure activity;
• a sense of his own heart, tachycardia , Heart pain, arrhythmia   (similar symptoms occurred at too rapid introduction of the drug);
• dyspepsia ;
• nausea   and   vomiting ;
• constipation   or diarrhea ;
• reaction injection site (erythema, burning sensation, local inflammatory reactions);
• pain in the neck and back (in the lower part), of course.

Because the drug is often used to treat elderly people, some of the side effects occurring during the clinical trials may not have a causal relationship with the reception of Cere (most of them occur in these patients not only during treatment with medication).

Some of the identified adverse effects occurred with similar frequency in patients receiving treatment drug, and patients treated with placebo (change in blood pressure, tremors, nausea, weakness, dizziness, shortness of breath, tremor, diarrhea).

Injections Cere: instructions for use

The drug is intended for intravenous and intramuscular administration.

B / Cerebrolysin administered alone at a dose of 5 to 10 ml. If the patient is a dose of 10 to 50 ml (the maximum tolerated dose), the solution is recommended to inject solely by slow intravenous infusion after prior dilution to 100 ml of a standard solution: Ringer's solution, isotonic NaCl solution, 5% glucose solution.

According to the instructions for use of Cere, in diluted form at room temperature and exposed to sunlight on site preparation is physically and chemically stable for days, but from the microbiological point of view, the solution for infusion should be introduced immediately after cooking.

The duration of treatment typically is from 10 to 20 days (assuming daily administration).

It allowed a one-time administration of the maximum dose of the drug (50 ml), but is considered a more effective course application Cere.

Of fundamental importance to achieve the clinical effect of therapy is the use of adequate doses of the drug diagnoses, as well as the right choice of method of administration.

Recommended daily doses:

• 5 to 30 ml - in the degradation of cognitive function, organic pathologies and metabolic brain disorders;
• 10 to 50 ml - to eliminate the effects of a stroke;
• from 10 to 50 ml - for the treatment of brain injury and its effects.

With neurological diseases children   injections are shown from patient administering 1 to 2 ml.

The recommended dose for children aged up to six months - 0, 1 ml per kilogram of body weight. The maximum daily dose for patients in this age group should not exceed 2 ml.

The effectiveness of treatment increases with each repeated course. Treatment is generally continued until until it is a significant improvement in the patient's condition.

During the initial course, the number of administrations could be reduced to 2 or 3 times a week. By the repeated courses should withstand the interval, the duration of which shall not be less than the duration of the preceding treatment.

The manufacturer does not release the drug in tablet form, so look for instructions on the pill Cere meaningless.

Overdose

Cere overdose cases have been identified.

Cooperation

The product is incompatible:

• medicine, the ability to change its pH (5, 0-8, 0);
• lipid-drugs.

Cere allowed to use with balanced solutions amino acids , from Vitamins , Drugs to treat diseases heart and vascular system However contraindicated to mix the medicaments in one bottle for infusion.

Particular attention is recommended to pay potentially possible pharmacological effects, while applying it to monoamine oxidase inhibitors (MAO) or antidepressants .

Terms of sale

To purchase the drug requires a prescription.

Storage conditions

Cere Guide recommends that you keep in the original packaging at a temperature not exceeding 25 degrees Celsius. Keep away from children.

Shelf life

For preparation in ampoules - 5 years, in the vials - 2 years from the date of issue.

Cautions

The drug is prescribed with caution in patients with allergic (exudative-catarrhal) diathesis .

Evidence that the drug may increase the burden on the kidneys   not, however, should not be administered to patients with severe renal failure .

In clinical studies there was no evidence of any impact of the drug on the ability to engage in activities requiring alertness and psychomotor speed, and the ability to operate a vehicle.

However, in some cases, there is a possibility of adverse side effects from psychiatric and nervous system, which in turn can temporarily disrupt the ability to drive and use machines.

The preparation of the final containers should be dialed immediately prior to injection infusion of ooze. It is allowed only one-time set of solution from ampoule or vial.

When the sludge or impurities in solution, and in the case of changing the color of the solution, its use is forbidden. Under normal circumstances, the color of amber liquid.

Analogs Cere

Match code ATC 4th level:

• Pantokaltsin
• Noben
• Cortexin
• Omaron
• Pantogam
• Pantogam Active
• Tiotsetam
• Noopept
• Kogitum
• Encephabol
• Tserakson
• Pikamilon
• Phenotropil
• Nootropil
• Vinpocetine
• Aminalon
• Fezam
• Pyracetam
• Cavinton
• Semaks

Analogs in Cere ampoules - a drug Amilonosar . Bravinton . Vinpocetine . Cavinton . Cortexin . Pyracetam . Lutset . Nootropil . Piracetam Bufus . Piracetam-Vial . Pikamilon . Tserakson . Tserebrolizat . Eskotropil . Vinpotropil . Tselleks . Tiotsetam .

In the drug also has analogues in tablets: Amilonosar . Lucidril . Vero Vinpocetine . Vinpotropil . Vinpocetine . Vintsetin . Ginkgo Biloba . Glycine . Idebenone . Gopantam . Cavinton . Calcium gopantenat . Ginkoum . Karnitsetin . Kombitropil . Lutset . Memotropil . Neyromet . Noben . Nooke . Noopept . Nootropil . Pantogam . Pikamilon . Pikogam . Piratsezin . Omaron . Pyracetam . Piriditol . Telektol . Pantokaltsin . Fezam . Phenotropil . Encephabol . Korsavin . Tselestab . Karniteps .

Cheaper analogs Cere - Tserebrolizat . Glycine . Nootropil . Tsinnazarin . Instenon .

For children

In pediatric practice Cere   apply where there is reasonable evidence.

During pregnancy (and lactation)

Conducted animal studies found no toxic effect of the drug on the reproductive system. However, data on how Cere may affect human reproduction, to date there.

In this regard it is administered to pregnant women only in those cases where there is no alternative therapy with Cerebrolysin. If necessary, the course of treatment during lactation, it is necessary to decide the issue of termination of breastfeeding.

Reviews cerebrolysin

As is the case with any other drug, reviews of physicians and patients about cerebrolysin can meet the most different. Moreover, many foreign experts believe its expensive pacifier with unproven efficacy. In addition, our doctors prescribe medication is quite common, and patients - if you believe the reviews left - often remain satisfied with the results of treatment.

For children injections are effective in the need to eliminate the effects of birth trauma When perinatal pathology central NA To reduce tension NA . In addition, the drug stimulates brain development and speech in children , Which was delivered diagnosis of "speech delay" .

However, many mothers say that the effectiveness of the medication depends on the correct selection of the dose and duration of treatment. Some believe that Cere works well in high doses or in combination with a complex physiotherapy activities.

According to parents whose children were treated with a drug, especially a pronounced progress in children can occur if the therapy was initiated about one year.

A number of negative reviews about cerebrolysin for children due to the fact that the injections quite painful, pricey and have contraindications.

Reviews adults about the drug rather contradictory. In forums where people discuss certain medicines, left a lot of positive feedback about cerebrolysin as on effective and proven means.

Some patients say they have not seen the desired effect. However, the instruction to cerebrolysin warns that the greatest clinical efficacy observed after not one but several courses of treatment.

Price Cere

Price vials of Cerebrolysin in Ukraine

The cost of 1 ml ampoules №10 - 200 UAH, buy 5 ml ampoules №5 can be around 330 USD. The vials of 10 ml №5 in Ukrainian pharmacies cost an average of 540 UAH.

Price Cere in Russia

Prices for injections Cere on the Russian pharmaceutical market of the following:

• 1 ml ampoules №10 - 660 rubles;
• 2 ml ampoules №10 - 910 rubles;
• 5 ml ampoules №5 - 970 rubles;
• 10 ml ampoules №10 - 1350 rubles.

Search price Cere tablets does not make sense, because the drug is produced exclusively in the form of a solution.

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Zopiclone

Description overdue on 21/10/2014

• Latin name: Zopiclone
• ATC code: N05CF01
• Active substance: Zopiclone (Zopiclone)
• Manufacturer: New Farm Inc. / Biotec MFPDK (Canada)

Photos of the drug

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use of zopiclone (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Synonyms
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

In zopiclone tablet contains 7, 5 milligrams of the same name of the active drug compound. In addition, such ancillary components as: microcrystalline cellulose, lactose monohydrate, potato starch, colloidal anhydrous silica, magnesium stearate , and talc, aerosil and povidone .

Product form

This drug comes in tablet form, which is applied on top of a special envelope and powder, packaged in special bags sachets.

Pharmacological action

The medicine refers to   sedatives and opiates, within the group   pirrolopirazinamidov .

Pharmacodynamics and pharmacokinetics

As a Zopiclone hypnotic derivative tsiklopirrolona,   preparation is effective agonists so-called benzodiazepine receptors . This medication is different pronounced anxiolytic,   and sedation . In addition, HP released its amnesic, anticonvulsant and muscle-relaxing properties.

Due to the chemical characteristics of the drug included in the drug zopiclone , Is amplified GABA-ergieskih processes in the brain human, thereby increasing the threshold of sensitivity to neurotransmitter GABA-receptors   due to interaction with the active components benzodiazepine receptors.   When receiving the drug reduced the number of awakenings during the night.

In addition, the drug has beneficial effects on the process of falling asleep and increases the duration of sleep. It is worth noting that the drug has no negative impact on the very structure of sleep, that is, It does not change its stage, for example, reduces the duration of REM sleep, and so on. The drug dissolves quickly enough in stomach   and reaches its maximum concentration already after a few hours after its administration.

The drug is easily overcome gistogematicalkie barriers   and evenly distributed in the tissues and organs of the human body, including the brain. If re-treatment Zopiclone cumulation   not shown. Within half an hour after using the drug comes deep sleep, the duration of which is a maximum of eight hours.

It should be noted that while taking zopiclone and medicaments containing composition theophylline , Patients with asthma   significantly decreases the duration and furthermore the intensity of asthmatic attacks in early morning hours.

Indications

Typically, the drug is prescribed in the following sleep disorders:

• difficulty falling asleep;
• permanent night or early morning awakening;
• insomnia, including chronic, intermittent or situational kinds of ailments;
• restless sleep;
• sleep disturbances associated with different types of psychiatric disorders.

Contraindications

Absolute contraindications include:

• hypersensitivity;
• pregnancy;
• respiratory failure;
• age 18 years;
• lactation.

In addition, with extreme caution must use this drug patients liver failure,   at sleep apnea syndrome,   at glucose and galactose malabsorption , In congenital   galactosemia At myasthenia And when lactase deficiency .

Side effects

With the correct dosage of the drug zopiclone side effects usually do not appear. However, significant excess doses may experience the following ailments:

• amnesia;
• behavioral disorders;
• aggressiveness;
• Sleepwalking;
• confusion or altered consciousness;
• rebound insomnia;
• psychological or physiological dependence;
• speech disorders;
• depression;
• loss of coordination;
• dizziness;
• ataxia;
• hallucinations;
• euphoria;
• headache;
• decreased sex drive;
• skin rash;
• diplopia;
• hypotension;
• angioedema;
• urticaria and other allergy;
• asthenia;
• dispersion;
• hypotension;
• vomiting;
• anorexia;
• diarrhea;
• weight reduction.

It is worth noting that in overdose patients experience   dry mouth and a bitter taste . In some cases, it may be increased liver enzymes .

Instructions for use of zopiclone (method and dosage)

Therapeutic (average) dose according to the instruction on Zopiclone (zopiclone) is 7, 5 mg., Corresponding to a single tablet. The drug is taken just before bedtime. In severe forms insomnia   dosage can be increased twice. However, patients in the elderly and people suffering from disorders liver function   It should not take more than 3, 75 mg. Zopiclone per day.

Overdose

Drug overdose occurs when exceeding the average recommended therapeutic dose of the drug and can threaten the patient's life. As a rule, in the event of an overdose occurs   oppression CNS (central nervous system). Symptoms of overdose may be considered sluggish condition of the patient , and drowsiness, confusion, respiratory depression, ataxia, hypotension and hypotension.

If it has been less than one hour after administration of the drug, it can cause the patient   vomiting . In other cases, you should immediately conduct gastric lavage While paying special attention to the protection Respiratory . In order to reduce absorption   contained in the drug zopiclone patients discharged Activated carbon .

Cooperation

Zopiclone is forbidden to take simultaneously with alcohol and alcohol-containing medicines. In addition, the drug reduces the effectiveness Trimipramina and a dampening effect on the nervous system drugs with anxiolytic, antidepressant, antihistamine, a sedative, anticonvulsant , and antipsihotropnym effect.

Terms of sale

According to medical prescription.

Storage conditions

Zopiclone is included in the list of drugs B, so the drug should be stored in a dry place, out of reach of children.

Shelf life

2 years.

Cautions

The risk of addiction can develop when too prolonged use of the drug. During the period of use of zopiclone it is forbidden to drink alcohol. The following day, after using this medication should refrain from driving or working with potentially dangerous machinery and apparatus.

Analogs of zopiclone

Match code ATC 4th level:

• Imovan

Among the analogues of zopiclone are the following drugs:

• Imovan;
• Relakson;
• Zopiclone 7, 5 - SL;
• Somnol;
• Piklodorm;
• Thorson.

Synonyms zopiclone

Zopiclone

Babies

Not recommended for patients under the age of 18 years.

During pregnancy (and lactation)

The drug is forbidden to take in the period Lactation or during pregnancy .

Reviews of Zopiclone

On the Internet you can find a wide variety of reviews of zopiclone. Many patients taking this hypnotic , Positive about its effectiveness. However, the negative aspects of the drug people often include an impressive list of side effects and note that Zopiclone is not suitable for long-term treatment of sleep disorders.

Price zopiclone, where to buy

The average price of Zopiclone (zopiclone) varies from region. For example, buy Zopiclone in Moscow can be as low as 550 to 1000 rubles.

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Dormikind

Description overdue on 04/12/2014

• Latin name: Dormikind
• ATC code: N05CX
• Active substance: Cypripedium pubescens D4, Magnesium carbonicum D10, Zincum valerianicum D12
• Manufacturer: DCU-Arzneimittel GmbH & Co. KG. KG (Arzneimittel GmbH & Co. KG)

Photos of the drug

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Dormikinda
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• Reviews
• Price, where to buy

Composition

The main part of the homeopathic remedy Dormikind includes three active ingredients:

• Cypripedium pubescens D4   - 15 mg;
• Magnesium carbonicum D10   - 20 mg;
• Zincum valerianicum D12   - 15 mg.

In addition to active substances, auxiliaries include:

• microcrystalline cellulose;
• talc;
• lactose monohydrate;
• magnesium stearate.

Product form

Dormikind - a patented homeopathic remedy Which is produced in pill form ploskotsilindricheskoy white. One vial 150 tablets.

Pharmacological action

Dormikind (Dormikind) is a natural complex German product, which, thanks to its unique composition of carefully selected materials, has beneficial effects on the child's body, helping to return to normal sleep. Acceptance of the drug relieves excessive irritability It eliminates feeling worry , Normalizes sleep.
It is noteworthy that the homeopathic preparation consists of natural ingredients and has no children hypnotic   or sedation And, therefore, do not cause drowsiness and dizziness during the period of its use. The tool is designed for use from birth. It is recommended to dissolve a tablet in a teaspoon of water before use for children from 0 to 4 years.
The active components of the drug effective for the symptoms such as nervousness, irritability, anxiety feeling.

Pharmacodynamics and pharmacokinetics

Pharmacokinetic and pharmacological data are not defined.

Indications

This drug is indicated for the treatment of worry   and sleep disorders   in infants and children.

Contraindications

Homeopathic remedies Dormikind contraindicated if the child is allergic (hypersensitive) to one of the active ingredients or any of the excipients included in its composition.

Side effects

Clinical studies have shown no side effects while taking Dormikinda except for possible allergic reactions . In the event of any adverse external manifestation of an allergic reaction, receiving homeopathic remedy need to stop and see a specialist for advice.

Instructions for use Dormikinda

Instructions on Dormikind simple enough. Tablets are taken half an hour before or after a meal. Experts recommend dissolve tablets for better absorption of active ingredients and the most effective impact on the child's body.

In the absence of contraindications for children from 0 to 6 years, the drug is taken 4 times a day 1 tablet.

For infants the drug must be dissolved before use in warm water (use a small amount of fluid - about 20-25 ml).

Overdose

An overdose of the drug can trigger the growth rate of negative responses (expression allergies   the drug).

Interaction with other drugs

Dormikind possible to take in conjunction with other medical drugs, as during clinical trials, the drug interactions of active substances with other components are not installed.

Terms of sale

The drug Dormikind released strictly in pharmacies. A doctor's prescription is required.

Storage conditions

This homeopathic remedy should be stored in a dry place at temperatures no higher than 25 degrees Celsius.

Shelf life

Up to 5 years.

Analogs Dormikinda

Currently preparations having a similar composition of the active ingredients Dormikind not exist.

Reviews Dormikinde

Dormikind is a homeopathic remedy, without causing virtually no side effects, except for allergy in children with hypersensitivity to the components included in the drug. Therefore, this tool is very often prescribed by pediatricians for hyperactive children with severe sleep disorders. Reviews moms are positive and confirm the effect of the means that can be traced in a few days for the first dose. There are also reviews of Dormikinde who are neutral. Experts attribute this to the fact that the homeopathic medicine works for every body at different rates of reaction, and therefore the effect of it is not always observed immediately.

Price Dormikinda

Dormikind can be bought in pharmacies at a reasonable price. Price Dormikinda per pack of 150 tablets varies in the area of ​​350 rubles.

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Anafranil

Description overdue on 07/12/2014

• Latin name: Anafranil
• ATC code: N06AA04
• Active substance: Clomipramine (Clomipramine)
• Manufacturer: Novartis Pharma AG, Switzerland

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

As a part of tablets is 25 mg hydrochloride klopiramida   + Corn starch, stearic acid, glycerol 85%, talc, copovidone, crystalline sucrose, disperse yellow colorant, microcrystalline cellulose, lactose monohydrate, colloidal anhydrous silica, magnesium stearate, hypromellose, titanium dioxide, polyvinylpyrrolidone K30, polyethylene glycol 8000.

One solution for injection ampoule   It contains: 25 mg hydrochloride klopiramida , Water, glycerol.

Product form

• The drug is released in the form of light-yellow tablets , Round, convex. 10 pieces in blister, 2 or 3 blisters in a carton box.
• Also agent is sold in a clear, colorless Injection Solution . The ampoules of 2 mL, 10 vials per bundle.

Pharmacological action

Antidepressant.

Pharmacodynamics and pharmacokinetics

Anafranil (Anafranil) - tricyclic antidepressant . Its main action is to inhibit reuptake noradrenaline   and Serotonin . This process is carried out by changing the concentration monoamines   in the central nervous system and blocking H2 gistaimnovyh   receptors.

Clomipramine   eliminates psychomotor   confusion, anxiety, bad mood. The active substance is able to eliminate night enuresis Which is not defined in the physiology of disturbances, it reduces appetite. There is the establishment of the transfer Serotonin   and adrenaline . The therapeutic effect is evident after the first week of dosing, effective reaches its maximum after 2-3 weeks.

With / m   the introduction of the drug is well and fully digested. 97% of funds is bound to plasma proteins.

The equilibrium concentration of drug reaches a maximum after 2 weeks of systemic administration. About 2% of the material is found in cerebrospinal   liquid. The drug penetrates well into the breast milk.

The preparation metabolized   by demethylation With the participation of enzymes CYP3A4, CYP2C19, CYP1A2 i Generated active metabolites. The duration of excretion from the body means 18 to 25 hours, depending on the method of administration.

Output metabolites   the urine and feces.

In elderly patients, the plasma concentration of the drug due to slow metabolism may differ materially.

Indications

Anafranil is prescribed:

• treatment depression   various origins ( Endogenous, neurotic, masked, involutional, reactive, organic depression );
• for depression in the elderly, due to constant severe pain or somatic   diseases;
• in depressive states have psychopaths   or schizophrenics ;
• in mood disorders neurotic, psychopathic   or Reactive   nature;
• treatment Panic Attacks   and various phobias ;
• at catalepsy   ( Narcolepsy );
• at presenile   and senile depression ;
• for prophylaxis migraine ;
• for the treatment of night enuresis Not associated with other diseases.

Contraindications

The drug is not prescribed:

• at allergies   on tricyclic antidepressants Groups dibenzazepine   or clomipramine ;
• if you recently had a myocardial infarction ;
• Children up to 5 years;
• pregnant and lactating women;
• when receiving MAO inhibitors   (two weeks before and after) MAO-A inhibitors reversible action;
• the syndrome of QTc QT .

Care should be taken:

• brain trauma;
• at epilepsy ;
• when combined with the drug neuroleptics ;
• persons with cardiovascular failure   or arrhythmia ;
• at glaucoma   or urinary retention;
• the elderly;
• adolescents;
• at tumors of the adrenal medulla ;
• people who have a tendency to rise constipation Particularly for bedridden or elderly people;
• in case of serious liver or hyperthyroidism ;
• at neuroblastoma   or pheochromocytoma .

When using the drug should be continuously monitored arterial pressure , To monitor intraocular pressure.

If the patient uses contact lenses, you should remember that the drug can reduce the intensity of lacrimation. This can result in damage to the cornea.

Particular caution should be observed with intravenous medications to avoid potential anaphylactic shock .

Side effects

Side effects Anafranil often mild, somewhat similar to the symptoms depression . Generally, the effects of such tested during treatment or after reduction and achievement of the minimum active dosage.

If serious adverse reactions and endanger the patient's life, the medication should be stopped.

Especially often and obviously side effects occur in the elderly.

There may be:

• drowsiness , Dry mucous membranes, fatigue, sweating, increased appetite, tremor ;
• constipation . myoclonus . headache , Visual disturbances, nausea, weight gain;
• paresthesia . tides , Palpitations, increased muscle tone, or weakness, speech disorders, mydriasis ;
• tachycardia , A strong decline BP Minor distortion ECG . vomiting . diarrhea , Epigastric pain, increased liver enzymes;
• hives . galactorrhea , Tinnitus, itching and rashes on the skin, breast enlargement, distortion of taste;
• violation of sleep, disorientation . hallucinations , Anxiety and aggression, delirium Memory problems;
• cramping, fever, ataxia , Changes in the electroencephalogram ;
• glaucoma , Violations intracardiac conduction , Urinary retention, swelling, burning and swelling at the injection site;
• pneumonitis . anaphylactic   and anaphylactoid reaction purpura . leukopenia . thrombocytopenia etc.

In a dramatic use means there is a withdrawal. Nausea, diarrhea, vomiting, irritability and anxiety, headaches, insomnia . The dosage should be reduced gradually.

Instructions for use (method and dosage)

If the patient hypokalemia Then before taking the drug it is necessary to eliminate.

The dosage and method of taking the medicine must be diagnosed by a doctor. Should be given the minimum active dose and gradually increase it until the desired effect is achieved. Older people and adolescents in the process should be treated with great caution.

Instructions on Anafranil tablets

The tablets are taken orally.

With depression, phobias   and obsessive compulsive syndrome   appoint one tablet 2-3 times a day. Dosage increases for 7 days on a tablet every 2-3 days. It is necessary to achieve a dosage of 100-150 mg. The maximum daily 250 mg. After achieving the necessary improvements in the patient's condition, he was transferred to 2-4 tabeltki per day (50-100 mg).

In chronic pain syndrome dosage is determined individually for each patient (10-150 mg per day). This should reduce the number of analgesics .

When the fear of open spaces and panic attacks   initial dosage is 10 mg per day. Further, continuous improvement is achieved by the daily dosage of 25-100 mg. Minimum course of treatment - six months (with a reduction in dosage).

With   catalepsy   and Narcolepsy   recommended amount of medication a day - 25-75 mg.

For elderly patients initial dosage administered 10 mg and then increased to 50 mg.

For children and adolescents initial dose - 25 mg per day. Number of Anafranil increase within 14 days and 100 mg. Further, for an additional 2 weeks the dosage is increased up to 200 mg. It is also possible to calculate the daily dosage of the principle of 3 mg of active ingredient per kg body weight.

At night enuresis : For children 5-8 years Dosage - 20 or 30 mg per day, between 9 and 12 - 25 or 50 mg, more than 12 years - 75 mg. A further increase in dosage is possible in the event that after a week of receiving a means of improving not come.

Tablets are better to drink before going to bed. The course of treatment - from three to three months. By the end of the course is necessary to gradually return to the original dosage and stop taking.

Instructions for use in injections Anafranil

Intramuscular injections

Treatment begins with the introduction of 25 to 50 mg, that is 1-2 ampoules. Thereafter, the dosage can be increased every day for one vial, the maximum dosage - 6 ampoules per day. Then, after the improvement in the state, the dosage should be reduced and replaced with tablets.

Intravenous

At the beginning of the treatment drug is administered drip, 2-3 capsules per day at a time. Duration infusion   from a half to 3 hours, the drug is diluted in 250-500 ml sodium chloride   or Glucose . During the procedure, the patient should be closely monitored to control the level Blood Pressure .

The treatment, even after the improvements need to keep 3-5 days, then the patient is transferred to the tablet.

This method of administration is not recommended for children and adolescents.

Overdose

Overdose means may suffer serious consequences, especially in children. Symptoms are similar for all groups of drugs tricyclic antidepressants .

Overdose symptoms appear within 4 hours after being hit by means of the body, the maximum number and severity occurs within hours. Within 5-6 days, the patient should be supervised.

In case of overdose occur: drowsiness , Anxiety, ataxia . convulsions , Increased body temperature, coma . delirium , Vomiting, respiratory depression, fever, severe drop in blood pressure, arrhythmia   and tachycardia . shock , Stupor, heart failure even in full cardiac arrest. FEATURES: anuria . cyanosis   or oliguria .

As the treatment is necessary to urgently perform gastric lavage. If the patient is conscious - cause vomiting, if not, to produce washing tracheal intubation . Call an ambulance, give the victim chelators   ( Activated carbon ). Perform the above operations it is advisable, even if after an overdose of more than 12 hours.

Specific antidote formulation has not, hemodialysis   and peritoneal dialysis   not applicable. Therefore, use of modern methods of intensive care, eliminate cramps, make artificial respiration.

Cooperation

Estrogens . cimetidine   and Methylphenidate   increase the plasma concentration clomipramine .

When combined with the drug ephedrine   and ethanol Their efficiency is increased, but increased the number and frequency of occurrence of adverse reactions.

Carbamazepine . rifampicin . phenytoin   and nicotine   reduce the concentration clomipramine   in blood plasma.

The drug is able to enhance the effect of antiparkinsonian .

In combination with the following drugs is the process of potentiation:

• from antithrombotic Drug ;
• beta-agonists ;
• from vitamin K antagonists ;
• from antihistamine drugs ;
• from isoprenaline   and biperidenom ;
• from norepinephrine ;
• from selective serotonin reuptake inhibitors .

Phenothiazines   when taken with the means to increase the burden of the central nervous system, intestine, bladder and increase the likelihood of seizure.

If you combine   antidepressant   from opioid analgesic . zolpidem   and other means, oppressive   CNS It may develop dangerous for the life of the patient's lethargy.

The drug enhances the effect on the body for drugs anesthesia .

Hormonal contraceptives   increase the likelihood of depression .

Levodopa   and furazolidon   in combination with means can greatly increase arterial pressure .

Preparations lithium   lower the threshold for seizure activity.

Simultaneous treatment with the drug betanidinom . clonidine   It can significantly reduce the effectiveness of the latter.

The combination and Anafranil atropine   enhances efficacy and adverse reactions of Mr. holinoblokatorov .

Precautions should be combined antidepressant   from disulfiram Since it contributes delirium .

MAO inhibitors When combined with the drug can cause whom . fever . hypertensive crisis   and convulsions .

Procainamide . quinidine   and thyrotropic drugs   increase the likelihood of abnormal heart rhythm.

The solution for injection should not be combined with reception diclofenac   in the same manner.

When combined with hepatotoxic drugs   Anafranil increases the load on the liver.

Terms of sale

Prescription.

Storage conditions

The drug is stored in a cool, dark place. No way to avoid getting money to the children.

Shelf life

5 years.

Cautions

In individuals predisposed to psychosis and the elderly drug can cause night delirious psychosis . After discontinuation of funds side effects of this kind take place.

During treatment, you can change the level of leukocytes , In connection with the need to monitor blood counts.

Caution should be exercised if the patient has a predisposition to constipation.

Patients with panic attacks   in the first days of treatment may be observed degradation usually feel adjusted in a week.

To combine the drug with electroshock therapy   It is only in the case of a thorough control of the state of health of the patient.

Receiving Antidepressants   increases the likelihood of suicidal thoughts , Attempts to suicide . This should be remembered by family members and the patient environment (guardian). Also, if such tendencies in a patient not previously observed, the drug should be discontinued.

While prescription should specify the minimum required at the moment the number of pills in order to avoid accidental overdose means.

Analogs

Match code ATC 4th level:

• Amitriptyline

Analogues: Klofranil, Doxepin, Anafranil Wed, amitriptyline, Melipraminum .

During pregnancy and lactation

The experience of the drug in pregnant women is limited. Cases of when the medication has caused malformations of the fetus. Therefore, the means may be imposed as a last resort, when it is impossible to do without it.

Infants may experience withdrawal symptoms if receiving funds was terminated later than 7 weeks before the birth.
The active substance passes into breast milk, so during breast-feeding   the drug should be discontinued (pre gradually reduce the dosage).

Reviews Anafranile

Reviews Anafranile forums for good. The tool helps to cope with intrusive thoughts and ideas, depression , Returned to the patient's will to live. However, the drug has a lot of side effects, and it has the right to appoint a doctor.

Price Anafranil

Price Anafranil tablets is about 300 rubles for 30 pieces of 25 mg.

Cost solution for injection - 640 rubles for 10 pieces of 2 ml.

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Likoprofit

Description overdue on 12/23/2013

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• Gerimaks
• Price Ribomunyl in Ukraine
• Composition Sedalgin Plus
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Dietary supplement for men.   Likoprofita Ingredients: selenium . chrome . zinc . minerals . lycopene (antioxidant) .   vitamin C . D . E . Likoprofit fort contains a complex of herbal extracts (bark of the African plum fruit palmetto, nettle root). The drug has a positive effect overall of the genitourinary system in males contributes to the maintenance function Prostate . The complex of minerals and vitamins has a positive effect on overall health.

Lycopene It is a carotenoid, and has expressed antioxidant effect . Selectively accumulates in the tissues prostate   Antioxidants protect cellular structures from the damaging effects of free radicals. Thanks to lycopene reduces the severity of autoimmune and inflammatory processes, slowing down the transition of testosterone to dihydrotestosterone. The carotenoid prevents excessive proliferation of cells in the tissues of the prostate. By increasing the number of normal active species sperm   It improves the quality of sperm. It is scientifically proven that the carotenoid lycopene reduces the risk of prostate cancer.

African plum bark extract   It has anti-edematous, anti-inflammatory effect, tones muscle group urinary tract and bladder, inhibits proliferation and inhibits the growth of fibroblasts. The extract of dwarf palm fruit   prevent proliferation of prostate tissue, blocks the activity of the enzyme 5-alpha reductase and has a decongestant, anti-inflammatory effects, which can significantly reduce the frequency of urination at night, to reduce the amount of residual urine. As a result of the complex action of normal urination, and decreases the severity of pain. Nettle root extract   It eliminates the main urination disorders and prevents the proliferation of prostate tissue.

Vitamin C is capable of supporting antioxidant enzymes, anti-inflammatory effect and increases the overall resistance of the organism. Vitamin E neutralizes the negative effects of free radicals (antioxidant effect), exerting a positive effect on sexual function in men. Vitamin D inhibits the excessive proliferation of prostate cells, promotes stimulation of immunity is involved in the regulation of heart muscle, prevents the formation of muscle weakness. Chrome   It is part of all cells and tissues; It helps to prevent abnormalities of the reproductive function. Selenium   It is an antioxidant and helps to normalize the functioning of the prostate. Zinc   reduces the severity of inflammatory reactions, has antimicrobial effect on the secretion of the prostate. The company " Ecomir "Produces a series of" Likoprofit Potential ", a formula which further comprises an extract of ginseng, yohimbe bark, leaves of ginkgo biloba. All of these elements are part of Likoprofit potential as a chelate complexes that are better absorbed in the body. Buy Likoprofit can be in the form of capsules (pack of 30 pieces of 500 mg).

Indications:

Likoprofit indicated for prevention of prostatitis, adenoma and cancer of the prostate. The medicament may be included in the combination therapy of the above diseases. Potential Likoprofit prescribed to increase sexual tone in males for stimulation and increasing the duration of erection, the stabilization of reproductive and sexual functions. The medicament may be used as an important and valuable source of biologically active substances. Reviews on Likoprofit indicate a high efficacy in the treatment of genital diseases in males.

Contraindications:

Likoprofit not indicated in case of hypersensitivity to the components. "Likoprofit potential formula" is contraindicated for insomnia, increased excitability of the nervous system, thyroid giperfunktsionirovanii, atherosclerosis, disorders of the heart rate, arterial hypertension.

Side effects, overdose:

Comments on Potential Likoprofit indicate a good tolerability of the drug. Cases of overdose have not been described.

Mode of application:

The drug must be taken daily, 1 capsule, a course - 1 month. Repeat courses possible within 3 months, if necessary. Instructions for use Likoprofita to take medication in the morning.

Special instructions:

Structural analogues Likoprofita not developed. To enhance the potency can be used tongkat ali Platinum (medicine plant prosihozhdeniya). Price Likoprofita pharmacies - 300-400 rubles.

Drug Interactions:

Pharmacological drug interaction potential Likoprofit with other medicines has not been described.

Tribestan

Description overdue on 04/16/2014

• Latin name: Tribestan
• ATC code: G04BX50
• Active substance: Tribulus stelyaschiesya, dry extract
• Manufacturer: Sopharma AD, Bulgaria

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Tribestan (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

One tablet contains Tribulus creeping dry extract 0, 25 r + excipients (microcrystalline cellulose Povidone, colloidal silica . magnesium stearate . crospovidone Polyvinyl alcohol, talc, red, yellow, and black iron oxide, lecithin , Xanthan gum).

Product form

The blister packs of 10 pieces, red-brown round convex tablets.

Pharmacological action

Lipid-lowering agents, treatment Erectile Dysfunction .

Pharmacodynamics and pharmacokinetics

Thanks steroid saponins , Which is part of the preparation, and mainly, protodioscine Restored libido and erectile function . Has a general tonic effect, it adjusts the hormonal balance in the period menopause . It stimulates the production of Testosterone   and increases the amount and quality of sperm .

When ingested, metabolized   before dehydroepiandrosterone Which in turn displays immunostimulating effect strengthens cholesterol metabolism   and improves the permeability cell membrane . The drug lowers blood cholesterol and favorably affects the tone small intestine It prevents the formation of blood clots .

After 3 hours after administration, the drug is excreted in the urine. It undergoes a small amount biotransformation   in the body.

Indications

• Decreased performance due to undergoing a severe illness, with mental and physical loads.
• Decreased sex drive and sexual dysfunction (for men: sexual weakness, poor sperm motility, to increase libido, increase the duration and strength of erection ; for women: menopause, frigidity, the postoperative period, infertility, hormonal origin ).
• To reduce the cholesterol , Disorders of lipid metabolism.

Contraindications

• bleeding tendency;
• allergy   on the components that are part of the drug;
• age 18 years;
• pregnancy and lactation.

Side effects

Upon receipt of funds to the food, there may be nausea and even vomiting, drug allergy.

Instructions for use Tribestan (method and dosage)

Tablets are taken orally after a meal.

Instructions on Tribestan and Tribestan Plus

When violations of men - 1-2 tablets 3 times a day. The course is 40 to 90 days. For women - 1-2 tablets three times a day maintenance dose - 2 tablets per day. With lipid metabolism disorders   - 2 tablets three times a day for 90 days.

Overdose

No information.

Cooperation

Care must be taken for women while taking pills stimulant Ovulation .

Terms of sale

It requires a prescription.

Storage conditions

In the reach of children, dry, cool place (below 30 degrees).

Shelf life

3 years.

Analogs Tribestan

Match code ATC 4th level:

• Brusniver
• Speman Forte
• Speman
• Urolesan
• Phytolysinum
• Kanefron
• Gentos

Analogues of the drug are: Gentos, kanefron district, urofloks, fitourolit, cystitis Aurina .

During pregnancy and lactation

In case of pregnancy, the drug should be discontinued. Combine breast and receiving Tribestan not worth it.

Reviews on Tribestan

Reviews of Tribestane good men, the drug actually increases the potency and libido, I felt a surge of strength and vigor. Those who took the drug on their own, without consulting a doctor, does not always help.

Reviews Tribestan women in plus and Tribestan positive, the drug is effective in the treatment of infertility . Many failed to become pregnant after taking, however, in the case of a combination with other drugs.

Some athletes used the drug in bodybuilding to improve performance. In most cases, significantly increasing the daily dose. When receiving such side reactions can occur in the form of skin rash.

Price Tribestan where to buy

The pharmacy price of 60 tablets in Ukraine will be about 251 USD. Price in Kharkov - 245 UAH for the same amount, in Odessa - 273 UAH, Donetsk - 230 UAH. Astana - 6642 m.

Buy Tribestan Plus   Ukraine is possible for 108 USD for 30 tablets. Buy the same amount of the drug in Moscow will cost about 560 rubles.

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The vaccine against meningitis B is called a breakthrough in preventive medicine

Get a recently licensed a new vaccine against meningitis B is the most significant achievement of preventive medicine from the time of the introduction of the polio vaccine. So says one of the UK's leading public figures.

Founder of charity to combat meningitis Meningitis UK Steve Deyman he lost a 14-month-old son Spencer because of meningitis and septicemia. He is confident that the new the vaccine against meningitis   B (caused by bacteria group) can save hundreds of thousands of children's lives around the world. The other day she passed licensing and can now be used in children aged between two months and older. The drug protects against most strains of the disease.

Bacterial meningitis   - The most common form of this disease, and the most deadly. In the UK alone the disease affects about 1 900 people a year (the majority of cases the children), killing every tenth of his victim. But to defeat the disease and has a hard time, as the common side effects of meningitis are severe brain injuries and amputations. The biggest risk for kids under the age of five years. In some cases, the disease can kill a child in just four hours!

At the disposal of medicine already available the vaccine against meningitis   C, Hib-meningitis and pneumococcal its varieties. The new vaccine, called Vexsero, aimed at protection bacterial meningitis .

"This disease is one of the main killers of young children - says Steve Deyman. - The new vaccine has the potential to save hundreds of thousands of lives. I think it is creating the biggest breakthrough since the release of polio vaccine in the late 1950s." (READ MORE)

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The test for breast cancer

If a woman takes hormone replacement therapy preparations of estrogen or progestin, and suddenly felt a pain in my chest, it may be a sign of developing breast cancer. Doctors recommend that in such cases, stop taking hormones and seek medical advice. But, unfortunately, many patients believe that hormone replacement therapy is struggling with pain in the breasts.

A recent study, which was attended by 8500 women taking hormone replacement therapy - progestin and estrogen, as well as the placebo group (so-called "dummy" - a harmless drug simulator) - another 8 100 females. Each year they should do mamogramma.

As a result, those who took hormones, complained of pain in the chest three times more often than in the placebo group. In the period of 5-6 years at 0, 6% of women complained of breast tenderness was indeed diagnosed breast cancer . Also, cancer was detected at 0, 36% of women taking hormones, but without chest pain. Thus, breast tenderness increases the risk by 48%.

Pain may be the first sign of breast cell division and cell proliferation (ie growth of tumors by the organism and cell proliferation) - it is a direct threat of breast cancer .

This finding applies only to those women who use combined hormone replacement therapy .

Meanwhile, in 2002, after the Women's League of Health were received statistics, which showed an increased risk of stroke, heart attacks, and invasive breast cancer in those receiving treatment Hormone replacement therapy First, women were advised not to use hormones for more than 5 years.

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