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Anthelmintic drugs . The principle is based on the impact of the depletion of glycogen stores in the body by helminth irreversible disturbance of glucose utilization. Active substance mebendazole decelerates synthesis of adenosine triphosphate, inhibits tubulin synthesizing cells. Vormin is available in tablet form (in a special blister 6 pieces).
Indications:
Tablets prescribed for Vormin echinococcosis , Teniasis, trihotsefaleze, ankilostomidoze, enterobioze, gnathostomiasis, capillariasis, alveococcosis disease , Multiple nematodes, Mixed helminthiasis , Strongyloidiasis.
Contraindications:
Tablets are not prescribed for Vormin Crohn's disease , Individual intolerance and severe allergic reaction to mebendazole, with non-specific form of ulcerative colitis, with gestation pregnancy failure, hepatic system, breastfeeding. Vormin children can be assigned after the two years.
Side effect:
Treatment Vorminom can be accompanied by headaches, nausea, dizziness, and epigastric pain, spastic nature. Prolonged treatment with mebendazole in high doses, in excess of the recommendations calls leukopenia , Diarrhea, vomiting, hypercreatininemia, eosinophilia, increased hepatic enzyme system, allergic responses in the form of angioedema, urticaria, rash and pruritus. In the cases observed cylindruria neoktorye, hematuria . Instructions for use of medication Vormin provides an indication of the possible negative effects of mebendazole on fetal development (formation of various forms of abnormal development).
Overdose:
Manifested diarrhea syndrome , Nausea, vomiting, epigastric, spastic pains. Receiving high doses the drug causes neutropenia The development of hepatitis and reversible disruption of work and functioning of the liver. In case of overdose with mebendazole it is recommended to induce vomiting, the most clear the stomach from the remnants of drugs, assign effective chelators , Activated carbon.
Mode of application:
Tablets Vormin recommended to drink water. Treatment of strongyloidiasis, ankolostomoza, ascariasis, teniasis, trichuriasis mixed infestations: for three days twice a day, take 100 mg of mebendazole. Treatment enterobiasis: single oral administration of 100 mg of mebendazole. With the high risk of re-infection, repeat the course in 2-4 weeks. Children 2-10 years appoint 25-50 mg Vormina. Treatment of trichinosis: three days take 200-400 mg of mebendazole three times a day; the next seven days, take 400-500 mg three times a day. Treatment of echinococcosis: Three days take mebendazole 500 mg twice daily; Three days later the amount of medicament Vormin increased to 1500 mg (for 3 doses); more drugs are given maximum dose which is calculated according to the following scheme: 25-30 mg per 1 kg body weight per day (for 3-4 hours). To prevent Vormin appoint regimen.
Special instructions:
It is forbidden to use alcohol during the first days of treatment . Prolonged treatment with mebendazole requires regular monitoring changes in peripheral blood, kidney function and liver system . Treatment Vorminom not require laxative treatment is recommended to refrain from a fatty meal . Upon completion of the course is a compulsory anthelmintic treatment study of fecal smears and anal area . Therapy found to be effective if, within a week after the last tablet in the stool and smear do not find the eggs of parasites or helminths themselves . Reviews on Vormin indicate a high anthelmintic activity of the drug, its good tolerability, even in children . The drug is practically not absorbed from the digestive tract . 90% of the active substance is excreted in the feces as unchanged, the remaining 10% is excreted via the renal system when urinating . Vormin price varies by region, the pharmacy chain (an average of about 50 rubles) . Vormin during pregnancy is absolutely contraindicated . Manufacturer's recommended storage temperature range of mebendazole - more than 25 degrees Celsius .
Drug Interactions:
Inductors metabolic processes and reduce the level of carbamazepine mebendazole concentration in blood, a reverse reaction occurs during concurrent therapy cimetidine . It is recommended to avoid sharing the treatment lipophilic drugs. In patients with diabetes Vormin may reduce the need for insulin .
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