Diane-35

Description overdue on 10.04.2012

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Means for contraception. The active component acts cyproterone   and   ethinylestradiol . The drug has a monophasic mechanism with androgenic activity. The principle is based on the impact of oppression on the development of pituitary gonadotropins level blocking androgen receptors. Cyproterone acetate is a steroid antiandrogens And ethinyl estradiol - oral estrogen. Under the influence of cyproterone decreases phenomenon androgenization   in females. Diane-35 has a gestagenic effect mimicking the hormonal properties of the female body. Under the influence of cyproterone inhibited the secretion of pituitary gonadotropins, slows down the process Ovulation That provides reliable contraception. Under the influence of ethinyl estradiol is a high viscosity of the mucus in the cervix, making it difficult the passage of sperm into the uterus; enhanced the severity of the central and peripheral cyproterone influence on the process of ovulation. Diane-35 is available in tablet form.

Indications:

Diane-35 is assigned as contraceptive And when hirsutism , Androgenetic alopecia origin, seborrhea, "vulgar" eels.

Contraindications:

Diane-35 is not prescribed for liver disease, pregnancy, intolerance of ethinyl estradiol, cyproterone, congenital hyperbilirubinemia , Liver cancer, stroke, thromboembolism , Hemangioma liver diabetes , Hypertension, myocarditis, coronary heart disease, ischemic stroke, heart disease, atherosclerosis, retinopathy , Breast cancer, sickle cell anemia, angiopathy, retinopathy, disorders of lipid metabolism, endometrial cancer, otosclerosis, idiopathic jaundice . hyperprolactinemia . In ulcerative colitis, depression, epilepsy, gallbladder disease, liver disease system, porphyria, tetany, chorea, mastitis , Uterine cancer, kidney disease, multiple sclerosis , Tuberculosis, in adolescence, varicose veins used with caution after specialist consultation.

Side effect:

Diane-35 can cause headaches, breast tenderness, vomiting, nausea,   stomachalgia , Depressed mood, changes in libido, weight gain, jaundice, generalized itching, thromboembolism, blurred vision, conjunctivitis, skin rash, swelling of the eyelids, intermenstrual discharge, thrombophlebitis . Long-term use may cause chloasma .

Mode of application:

Diana 35 taken once daily, orally, the first day of the menstrual cycle. It is recommended to take daily medication at the same time. Duration of reception - 21 days, then make a seven-day break. When androgenization treatment may last for several months, even after the disappearance of obvious signs of disease treatment is continued for 3-4 cycles. When relapse repeat the treatment. In addition, cyproterone is added to therapy for ineffective treatment of alopecia (12 months), and seborrhea acne   (6 months). Omitting pill Diane-35 take the next 12 hours. When the interval between taking the pill more than 36 hours is recommended to use additional funds for the prevention of conception.

Special instructions:

The contraceptive effect is fully manifested only after two weeks of taking the drug Diane-35, which requires the use of additional, non-hormonal contraceptive methods. During the period of administration of the drug may reduce the level of FSH, LH, changes in the results of allergy tests. During the formation of a normal menstrual cycle, the drug has no effect on the course puberty . After birth, Diane-35 is prescribed only after the first, healthy menstrual cycle. It is not recommended to interrupt the therapy abruptly even when a intermenstrual bleeding within three weeks of taking the pills. The seven-day break come like menstrual discharge. In their absence it is necessary to exclude pregnancy. Every six months, be sure to pass gynecological, medical examination (Optional surveyed breast). Upon the occurrence of pregnancy signs phlebothrombosis , Phlebitis, jaundice, migraine treatment ceased. Reliable contraception decreases vomiting, diarrhea. The likelihood of developing serious cardiovascular diseases increases with the cigarettes smoked, the age of women (most susceptible women older than 35 years).

Drug Interactions:

Rifampicin , Ampicillin and some antibiotics reduce the effectiveness of the drug, due to changes in the intestinal microflora, and requires the use of additional methods of protection against conception. Phenytoin and number antiepileptics   enhance the metabolism of steroid hormone drug Diane-35. It requires consultation endocrinologist to address the issue of correction of hypoglycemic medication dispensing.