Description overdue on 11/28/2014
- Latin name: Noben
- ATC code: N06BX13
- Active substance: Idebenone (Idebenone)
- Manufacturer: Binnofarm JSC (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Nobena
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Synonyms
- Babies
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One capsule, as an active ingredient contains 30 mg idebenone .
Additional ingredients:
- 102 mg - lactose monohydrate;
- 39 mg of 4 - potato starch;
- 20 mg - microcrystalline cellulose;
- 8 mg - povidone;
- 0, 6 mg - magnesium stearate.
Product form
Noben medicament is produced in the form of capsules, 30 units in a single package.
Pharmacological action
Nootropic.
Pharmacodynamics and pharmacokinetics
Idebenone activates processes ATP synthesis and Glucose Increases blood supply and the volume of the incoming oxygen in tissue brain Thereby improving occurring in it metabolic processes and facilitating the removal of lactates . Being antioxidant It inhibits lipid peroxidation, thus protecting it from damage and mitochondrial membranes of neurons.
Noben shows nootropic with parallel action neuroprotective and psychoactive effect. Renders antidepressant . psihostimulirutee and antiastenicheskoe effect from the first day of its application, followed by a 20-25 day mnemotropnym and nootropic effect.
When taken orally, the contents of the capsule Nobena rapidly absorbed from the gastrointestinal tract. The highest concentration idebenone in the blood observed after 4 hours. The active ingredient easily passes BBB and distributed in brain tissues significant quantities. Even with a long reception not koumouliruet . T1 / 2 of about - 18 hours. Metabolism occurs in the liver. Output to a lesser extent and in faecal excretion greater.
Indications
The indications for use of the drug are different Noben tserebrastenicheskom disorders traumatic, vascular, psychogenic ( neurasthenia ) Nature and their combination, which are accompanied by: attention disorders and / or memory For lowering the total activity and intellectual performance, emotional disorders . asthenic . depression , Asteno depressive states . dizziness . headaches , Tinnitus.
Efficiency proven at Nobena psychoorganic syndrome , Provoked circulatory disorders of the brain And its involutional age-related changes .
Contraindications
- hypersensitivity Idebenone or other ingredients Nobena capsules;
- renal failure severe.
Side effects
- dyspepsia ;
- allergic reactions ;
- hyperphrenia ;
- violation of falling asleep ;
- headache .
Instructions for use Nobena
The drug Noben recommended to take orally (by mouth), preferably after a meal. Generally, a daily dose of idebenone is 60-90 mg, with the reception of first capsule (30 mg) was 2 or 3 times a day. Patients are advised to distribute the capsules so that would be the last to hold the reception to 17 hours, in order to prevent problems sleep Related to possible increased arousal .
The duration of the Nobena, usually from 1 5 to 2 months. Based on the severity of the disease and symptoms, recommend carrying out 2-3 courses of treatment for 12 months.
Overdose
In case of receiving high doses of idebenone , May increase its side effects.
In this case illustrates the application of conventional, under such circumstances, measures to prevent complications, including gastric lavage , Reception absorbents ( Activated carbon ) And symptomatic therapy.
Cooperation
At this time Nobena interaction with other drugs is not established.
Terms of sale
Holiday Message from the pharmacy is only possible to provide a doctor's prescription.
Storage conditions
The capsules are stored in original package in a dark place inaccessible to children at an ambient temperature of 30 ° C.
Shelf life
36 months.
Cautions
When the need for precision or dangerous work, as well as driving the vehicle, taking Noben prohibited.
Analogs Nobena
Cere
Cortexin
Omaron
Pantogam
Pantogam Active
Tiotsetam
Noopept
Kogitum
Encephabol
Tserakson
Pikamilon
Phenotropil
Nootropil
Vinpocetine
Aminalon
Fezam
Pyracetam
Cavinton
Semaks
In the pharmaceutical market there is quite a large amount of drugs, similar to idebenone in their action. The following are only the most common of its peers:
- Amilonosar ;
- Vinpocetine ;
- Glycine ;
- Cavinton ;
- Cortexin ;
- Lutset ;
- Nootropil ;
- Omaron ;
- Pyracetam ;
- Tiotsetam ;
- Cere ;
- Encephabol etc.
Synonyms
- Idebenone ;
- Neyromet ;
- Tselestab .
Babies
The decision to use Nobena childhood takes only pediatrician, given the evidence and all possible risks.
With alcohol
Do not combine the reception idebenone and alcoholic beverages.
During pregnancy (and lactation)
Periods breast-feeding and pregnancy are contraindications to the use of capsules Nobena.
Reviews Noben
Almost all of the reviews on the forums Noben extremely positive. It is very rare to find a disapproving statements about this drug, and those are not linked with the efficiency of its action, and the problem sleep and hyperexcitability That may be associated with high doses idebenone or taking the capsules in the evening.
Otherwise, the efficiency, speed of action and lack of adverse drug reactions in a plurality of treatment neurological diseases , Cerebrovascular, depression . emotional disorders and others, supported by experience Nobena use a variety of patients. Also, the action gets an approving assessment idebenone on intellectual activity , Increased attention Memory Improvement .
It is worth mentioning that self-appoint themselves any medications, and even more drugs nootropnogo action impossible. For successful treatment should always consult with a specialist who will select the adequate preparation of your condition and prescribe appropriate treatment.
Price Nobena where to buy
Price Nobena pharmacies Russia, an average of 300 rubles.
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