Jess

Description overdue on 11/14/2014

• Latin name: Yaz
• ATC code: G03AA12
• Active substance: Drospirenone + ethinylestradiol (Ethinylestradiol + Drospirenone)
• Manufacturer: Bayer Schering Pharma AG (Germany)

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• Composition
• Product form
• Pharmacological action
• Pharmacokinetics and pharmacodynamics
• Indications
• Contraindications
• Side effects
• Instructions for use Jess (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• With alcohol
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

Birth control pills contain Jess as part of the active substance ethinylestradiol   (Form betadeks clathrate ) Are also included in the active ingredient Ges Drospirenone .

Furthermore, the tablets include additional ingredients: corn starch, lactose monohydrate, magnesium stearate.

The composition of the shell of the tablet includes hypromellose, titanium dioxide, talc, dye.

Product form

Hormone pills Jess covers film coating.

Active tablets are round, biconvex, have a light pink color. On the one hand - engraved «DS» in the hexagon, on a break tablet white core.

Placebo tablets are round, biconvex, white film covers their shell. On one side of the tablet - engraved «DP» in the hexagon. On a break - white core.

The tablets contained in blister packs of 28 pieces.

Pharmacological action

Abstract indicates that the drug is Jess monophasic oral contraceptive, which also has on the anti-androgenic and anti-mineralocorticoid influence.

Contraceptive suppresses Ovulation , And also affects the cervical secretion, whereby the sperm can not penetrate through it freely.

Those women who take this medication, note that monthly cycle they have a more regular menstruation becomes mene painful and bleeding - not as abundant. As a consequence, reduces the risk of anemia . When using combined oral contraceptives are also less likely Ovarian Cancer   and endometrial .

Active ingredient Drospirenone has antimineralocorticoid effect on the body. Under its influence to prevent the accumulation of extra kilograms in the body, as well as edema. He has a positive effect on the condition of women during PMS, reducing the intensity of the psycho-emotional disorders, chest pain in the joints, and other unpleasant symptoms.

There antiandrogenic activity of this component, which determines a positive effect on the skin. As a consequence, the number of acne, reduced fat content the level of skin and hair. Effect of drospirenone similar to the action of the natural progesterone   in the body.

Estrogenic, androgenic, glucocorticoid and antiglucocorticoid activity in drospirenone missing. Combined with ethinyl estradiol, drospirenone acts favorably on the lipid profile.

Pharmacokinetics and pharmacodynamics

Drospirenone   after oral absorbed rapidly and almost completely. The maximum concentration observed 1-2 hours after ingestion. The level of its bioavailability is 76-85%. The bioavailability is not dependent on communication meals and medication. When receiving Maximum serum level of drospirenone is noted between the 7th and 14th day of treatment.

After receiving the internal Drospirenone is extensively metabolized. Only a small portion of the substance excreted unchanged. Metabolites are excreted through the kidneys and bowels. The substance is well tolerated by patients with liver failure in the mild to moderate form.

Ethinylestradiol   Once inside absorbed completely and quickly. After the use of single maximum concentration observed after 1-2 hours. Bioavailability component is about 60%. Completely metabolized by aromatic hydroxylation. The metabolites are excreted in the bile and excreted in the urine.

Indications

Jess - birth control pills, so their main indication - reception for contraception. The drug may be administered for the treatment of acne in a mild form and to eliminate severe symptoms of premenstrual syndrome.

Contraindications

Notes the following contraindications for receiving Jess:

• venous and arterial thrombosis   and thromboembolism   (in history, at the moment), cerebrovascular disorders;
• thrombosis previous state;
• migraine   (history, currently);
• diabetes Complicated vascular symptoms;
• manifestation of the presence of risk factors in women venous or arterial thrombosis;
• pancreatitis   with hypertriglyceridemia (history, currently);
• severe liver disease, liver failure;
• malignant liver tumors (anamnesis, currently);
• renal failure   in severe and acute;
• malignant hormone-dependent diseases, a suspicion on their development;
• adrenal insufficiency;
• vaginal bleeding of unknown origin;
• suspected pregnancy;
• breast feeding;
• High sensitivity to the ingredients of the preparation.

Caution should take the drug if any of the factors contributing to the appearance thromboembolism . thrombosis As well as other diseases where possible manifestation of peripheral blood flow. Be wary of any contraceptive indicated for diseases of the liver, hypertriglyceridemia Hereditarily angioedema .

Jess care imposed on women in the postpartum period, as well as those who have observed the disease caused or aggravated during pregnancy or while taking hormones. This can be cholelithiasis . cholestasia . otosclerosis . porphyria . herpes   and etc.

Side effects

There have been those most common side effects Jess:

• nausea;
• irregular periods;
• bleeding from the genitals of unknown origin;
• breast pain.

Serious side effects of the drug, which manifests itself in rare cases - thromboembolism   (venous, arterial).

Also sometimes observed following side effects:

• migraine ;
• depressed mood, mood swings, decreased sex drive;
• erythema multiforme .

It provided a number of side effects which are very rare, but they may be associated with the use of funds Jess:

• tumor;
• erythema nodosum ;
• hypertension ;
• worsening symptoms of angioedema;
• disruption of the liver ;
• effect on insulin resistance, changes in glucose tolerance;
• Crohn's disease ;
• chloasma ;
• ulcerative colitis ;
• symptoms of hypersensitivity.

Instructions for use Jess (method and dosage)

If a woman chooses the pill Jess, instructions for use must be clearly demonstrated it. Instructions on Jess stipulates that the tablets should be taken strictly in the order, which is indicated on the packaging. Daily medication should be taken at approximately the same time, drink it a scant amount of liquid. Instructions for use Jess involves taking one pill a day for 28 days. New packaging should begin the day after the woman drank the last tablet of the previous package. As a rule, the bleeding may start 2-3 days after the cancellation occurred.

If the woman in the previous month did not take any hormonal contraception, reception Jess begins on the first day of the menstrual cycle. Possible initiation of 2-5-day cycle, but it is desirable to use additional barrier contraception during the first seven days of tablet Jess.

How to take pills when you go to them after other methods of contraception, should ask the gynecologist who recommended this drug.

After an abortion in the early stages, you can start taking Jess immediately, with additional contraceptive measures are not needed.

If the birth took place or abortion in the second trimester, the reception Jess OK desirable to begin at 21-28 day after that.

In that case, if a woman missed tablet which is inactive, it can be ignored. But we should not take the missed inactive pill, for which they are released.

If skipping occurred tablet which is active, and wherein the delay does not exceed 12 hours and then the protection is not reduced. It is necessary as soon as possible to take the drug. If the delay exceeds 12 hours woman 2 tablets missed or break was even longer, in such a case, the level of protection is reduced. Accordingly, the longer there was a break, the greater is the likelihood of fertilization.

Thus, the consequences of stopping Jess follows: if it is 4 days or more, the chance of pregnancy increases significantly. To happened adequate suppression of the hypothalamic-pituitary-ovarian system, you must take the pills continuously for seven days.

Therefore, when skipping a woman needs to take the next pill as soon as possible, may be taking two tablets at once. Then continue receiving active tablets in the usual time. Inactive need to throw it away and start a new pack. In this case, the bleeding when taking unlikely, however small allocation at reception may occur.

If during the reception there was a break of use of active pills, and in the days of receipt of inactive pills bleeding is not mentioned, it is sure to exclude pregnancy.

In case of serious gastrointestinal disorders possibly incomplete absorption of active substances. In those days, the need for additional contraception. If the woman is vomiting within 4 hours after ingestion of the tablets, you should act as if skipping pills.

How to stop taking the tablets and thus move on to other methods of contraception, it is advisable to ask detailed specialist gynecologist.

Overdose

There is no information on the serious cases of drug overdose. As a result of an overdose of a woman may experience nausea, vomiting, appearance of spotting and metrorrhagia. Symptomatic therapy.

Cooperation

With the simultaneous use of other drugs, and Jess (number of antibiotics, inducers of enzymes) can cause a manifestation of breakthrough bleeding, as well as reduce the level of reliability.

In an application with Jess drugs that induce hepatic microsomal enzymes (this barbiturates . primidone . carbamazepine . phenytoin . rifampicin   et al.), increases clearance of sex hormones.

Under the influence of some antibiotics   may reduce the enterohepatic circulation of estrogen and, accordingly, reduced concentration of ethinyl estradiol.

During the simultaneous reception of drugs that influence the microsomal enzymes, and for 28 days after withdrawal of such drugs require additional contraceptive. Additional need contraception for 7 days after administration of ampicillin and tetracycline.

Jess may affect the metabolism of other drugs.

To determine the likelihood of interactions with other drugs Jess, you must carefully familiarize themselves with the instructions to them.

Terms of sale

In pharmacies sold by prescription.

Storage conditions

Keep Jess needed at temperatures up to 30 ° C, protect from moisture and reach of children.

Shelf life

You can store 5 years.

Cautions

If you have certain risk factors before taking Jess have to weigh the feasibility of using this particular means of contraception.

It should be noted that in the course of studies have found a link between protection by means of oral contraceptives and increased frequency of symptoms of thromboembolism, venous and arterial thrombosis. However, these diseases are rarely observed. Higher risk of thrombotic events observed in smokers, at an older age, obesity, migraine, diseases of the heart valves, dislipoproteinemia, atrial fibrillation.

With an increase in the intensity and frequency of migraine need to stop taking Jess.

There is also a risk that cervical cancer   women with persistent HPV infection .

Rarely, women who took oral contraceptives, marked the development of benign liver tumors. In very rare cases, malignant liver tumors were noted.

Women who have a high risk of manifestation hyperkalemia Should determine the level of potassium in the blood during the first cycle of drug use Jess.

Women with hypertriglyceridemia   I should consider that when taking Jess have increased risk of pancreatitis.

If during the period of administration of the drug the woman is expressed by an increase in pressure, oral contraceptives should be discontinued. If the means of antihypertensive treatment fails to normalize the blood pressure parameters, then pills can be extended further.

In acute or chronic hepatic impairment should be abolished means as long as the state becomes normal.

In the process of using combined oral agents may change some laboratory parameters, but for the normal range, they do not go.

Jess as other combined oral contraceptives can not protect against diseases that are transmitted by sexual as well as HIV-infection.

Using tablet to protect Jess, a woman said that when receiving no monthly. Sometimes, more often in the first few months, she notes that the menstrual cycle becomes irregular. Typically, the adaptation period continues for three cycles.

On the ability to focus the reception facilities are not affected.

Analogs Jess

Match code ATC 4th level:

• Femoden
•   Jess Plus
• Zoeli
• Dimia
• Mersilon
• Lindinet
• Miniziston
• Silest
• Rigevidon
• Yarina

Analogs of the drug Jess - it contraceptives Jess Plus . Midian . Dimia . Yarina . There are other analogs by various manufacturers, which are oral contraceptives. How to take similar drugs, and which one should prefer to ask the gynecologist.

Unlike Jess by Jess plus the fact that the preparation contains Jess Plus levomefolat calcium   or folate . Folate belong to the B vitamins in the body, they are not synthesized, so sometimes when you select - Jess and Jess plus - Women prefer the latter. What else is different, plus Jess and Jess, and which prefer tablets, is to ask the gynecologist.

Dimia or Jess - which is better?

Dimia - oral contraceptive which contains similar components in the composition. It is a cheaper analog of Jess. However, the final decision on the choice of the drug should be taken by the doctor.

Which is better: Klayra or Jess?

Klayra - a low-dose oral contraceptive, which is contained in the composition of the active substance valerate . This drug is indicated for the reception of women who are in the body there is a high level of estrogen. As a rule, Klayra recommended for women over the age of maturity.

Is it better or Yasmin Jess?

Yasmin - a low-dose contraceptive single phase, which has anti-androgenic effect and antiMKS. Yarina positively affects the skin, hair, does not cause weight gain. Components identical in both formulations, the dose of ethinyl estradiol differs only.

Which is better: jess or Janine?

Janine - combined estrogen-progestin contraceptive, as part of which contains ethinyl estradiol and dienogest. When receiving Jeannine women often notice some side effects, although the drug is as a reliable means of contraception.

Logest or Jess - which is better?

As part of the contraceptive Logest contains ethinyl estradiol and gestodene. Side effects and effects on the body similar to the action of the drug Jess. However, to choose the optimal oral contraceptive may be a doctor.

Jess and Diane 35 - which is better?

Preparation 35 Diana having progestational properties, its composition contains ethinylestradiol and antiandrogen cyproterone acetate. Upon receipt of Diana 35 women often notice a slight weight gain and some other side effects.

Babies

Teenage girls may use Jess after the first month.

Sometimes teens that acne drug is given. Reviews of Jess acne show the effectiveness of this drug.

With alcohol

Jess and alcohol can be combined if a woman consumes alcohol in small amounts and infrequently. Alcohol does not reduce the effectiveness of oral contraceptives.

During pregnancy and lactation

Pregnancy and breast-feeding is a contraindication for receiving Jess. In that case, if it is determined the pregnancy when taking the tablets need to immediately suspend oral contraceptives. Proedennye studies suggest that if pregnancy occurs after taking Jess, no adverse effects were observed in the child.

Since oral contraceptives can negatively influence the composition and quantity of breast milk, they are not recommended for women to stop breastfeeding.

Reviews of Jess

Online you can find numerous reviews about Jes tablets. Typically, these contraceptives women evaluate positively, although there are also reviews of the pill Jess those hormonal drug that did not fit. As a result, hormone pills provoked a manifestation of side effects, such as nausea, malaise, headaches and others. In this case, the woman tried to pick up another, more appropriate drug.

Doctors about Jess positive, as experts point out the effectiveness of the tablets Jess OK, and their overall positive effect on the body. Reviews of Jess in the forums also indicate that the drug helps to get rid of acne and improve skin condition. After the cancellation of contraceptive state of the body is not getting worse, so most of the women speaks positively about these pills.

The price of Jess, where to buy

Price pill Jess is 800-900 rubles per pack. Buy Jess in Moscow at any pharmacy.

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