Tuesday, November 27, 2018

Paracetamol

Description overdue on 23.09.2011

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 Paracetamol  The preparation paracetamol   It has antipyretic, analgesic and anti-inflammatory (moderately) properties. After receiving his depression occurs excitability thermoregulation center. In addition, the tool depressing synthesis prostaglandins Which are mediators of inflammation with a strong organic effect. Drug absorption takes place in the upper intestine. The process is quick, and wherein the active substance in the body throughout all tissues. Its metabolization in the liver, thus formed glyukorangid   and Sulfate of paracetamol That are excreted through the kidneys. After the use of the highest drug concentration in the body takes place after 30-40 minutes. Within half an hour the drug begins to act zharoponizhayusche.

Indications and methods of use of the drug:

The drug is used to assign patients with pain syndromes of diverse backgrounds who have light or medium intensity. Treatment takes place symptomatically. Indications for paracetamol are toothache and headache, myalgia   and neuralgia . algomenorrhea , Pain in the back, arthralgia . Also, paracetamol is effective in conditions involving hyperthermic reaction in patients with infectious and inflammatory diseases.


Adults can use a single dose of paracetamol 0, 35-0, 5 g three to four times daily, the highest single dose in this case is 1, z is 5, the maximum daily dose - 3-4 g of the drug. Paracetamol should be taken after a meal, drink plenty of pills needed. Children aged 9 to 12 a day can take no more than 2 grams of the drug. Children aged 3 to 6 years, a day can take no more than 1-2 grams of the drug.

Rectal suppositories   Paracetamol for children from one month to three years is prescribed at a dose of 15 mg per 1 kg of body weight of the child. At night you can take no more than 60 mg per 1 kg of body weight of the child. Taking the drug divided by 3-4 times. Adults and adolescents, weight exceeding 60 kg, One can take 0, 35-0, 5 g paracetamol, while in reception is allowed one day, 5 g, divided dose 3-4 times. Children from 6 to 12 years are allowed per day dose of 2 g, divided into 4 doses. Children from 3 to 6 years old, the dose per day is allowed 1-2 grams of paracetamol, divided into 3-4 receptions. Children paracetamol syrup for children from 3 to 12 months, take 2, 5-5 ml. Children from 1 year to 5 years are designated 5-10 ml syrup. Children from 5 to 12 years - 10-20 ml of paracetamol syrup. Adult patients and children whose weight exceeds 60 kg, appoint 20-40 ml syrup. Receive data divided doses 3-4 times per day.

Contraindications and possible side effects:

Do not use the drug to patients having a high sensitivity to the paracetamol. Also this drug is contraindicated in patients with hepatic and renal failure. Rectal suppositories of paracetamol should not be used in patients with inflammation of the rectal mucosa .

Very carefully appointed paracetamol during pregnancy and during breastfeeding. As a side effect may be a manifestation of a number of reactions. The work of the blood may be a manifestation anemia . agranulocytosis . leukopenia , Thrombocytopenia. The work allocation system may experience renal colic, glomerulonephritis . aseptic pyuria . In the nervous system can occur sleepiness or irritability. In the cardiovascular system may decrease the contractility of the heart muscle. In the gastrointestinal tract may occur epigastric pain and nausea. If you use the drug sufficiently long period and in high doses, it can manifest hepatotoxicity. It is also possible expression of a variety of allergic reactions. With an overdose of the drug can have toxic effects on the liver. For this condition characterized by drowsiness, pale skin, dizziness, vomiting and nausea. If you have these symptoms need urgent professional help.

Specific recommendations:

Paracetamol can greatly increase the impact on the body caffeine . salicylic acid . codeine And antispasmodic action. Paracetamol should be stored in a place protected from the reach of children. The temperature should not exceed 25 degrees Celsius.

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