Description overdue on 07/07/2014
- Latin name: Fanigan
- ATC code: M01AB55
- Active substance: Acetaminophen (Paracetamol) + Sodium Diclofenac (Diclofenac)
- Manufacturer: Kusum Healthcare Pvt Ltd (India)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Fanigana (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
The composition includes tablets Fanigan 500 mg acetaminophen and 50 mg diclofenac sodium (per tablet) also add additional ingredients: polyvinylpyrrolidone, starch, croscarmellose sodium, propylparaben sodium, magnesium stearate, microcrystalline cellulose and dye.
Product form
Is produced in the form of orange or 4 tablets of 10 tablets per blister. In the first case one carton blisters 25, 10 in the second.
Pharmacological action
Diclofenac and paracetamol Belonging to the Fanigana, it causes a significant anti-inflammatory and antipyretic effect, good painkillers.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The mechanism of action of the drug is associated with inhibition of prostaglandin synthesis As well as its effect on Pain Center and heat regulating center Which are hypothalamus .
Pharmacokinetics
After oral administration, the drug is rapidly and completely absorbed. Eating food has no effect on the rate of absorption. The concentration of active substances in the blood plasma are directly proportional relationship with the dose use of the drug. The maximum concentration is achieved after 60-90 minutes after administration. The drug entering the blood, nearly 100% bound to plasma proteins, moreover, it has the ability to enter the synovial fluid . Fanigana maximum concentration occurs in synovial fluid for 2-3 hours later than in the blood.
Diclofenac 60% was excreted in the urine, while the remaining 40% - with feces and bile. Paracetamol destroyed in the liver and excreted in the urine.
Indications
Indications for use of the drug a lot. The main syndrome of Fanigana from what drink it is pain syndrome . That is, in addition, from which tablets Fanigan help, such symptoms include:
- pains, which cause inflammatory and destructive form rheumatic diseases ;
- diseases of the spine;
- attacks gout , Trauma (eg, bruises or sprains);
- pain in the postoperative period;
- severe attacks migraine ;
- renal and hepatic colic ;
- some gynecological diseases;
- otitis ;
- pharyngitis ;
- tonsillitis ;
- toothache;
- neuralgia ;
- sciatica ;
- pain in the muscles and joints after exercise.
Contraindications
Contraindications for the purpose Fanigana are:
- intolerance to one or more components Fanigana;
- a history of symptoms allergies Arising after taking any drug, belonging to NSAIDs ;
- gastric ulcer and duodenal ulcer ;
- decompensated in lesions of the liver and kidneys;
- shortcoming glucose-6-phosphate dehydrogenase in the body;
- various violations of the formation of blood cells of unknown etiology;
- age up to 14 years;
- pregnancy and lactation.
Side effects
Typically, the use of Fanigana well tolerated. In some cases, nausea, vomiting, intestinal disorders ( diarrhea or constipation ), Acute ulcerative colitis . It can also be a headache, dizziness Sometimes - drowsiness , Weakness, irritability, sleep disturbances and sensitivity, taste, vision, appears skin rash . bullous rash . hives . eczema .
The plasma is sometimes increased levels of liver enzymes, in rare cases, a hepatitis . It is also possible manifestations tachycardia , Increased blood pressure, pain in the retrosternal area, bronchospasm . systemic anaphylaxis with lowering blood pressure. In some cases, symptoms can appear vasculitis, pneumonitis, acute renal failure, proteinuria, hematuria, nephrotic syndrome a May reduce the amount of leukocytes, platelets in the peripheral blood, develop hemolytic or aplastic anemia It can also be observed development agranulocytosis .
Instructions for use Fanigana (method and dosage)
The dosage of the drug individually appoint a doctor in accordance with the general instructions for use of tablets Fanigan, but depending on the features of the person: age, type and course of the disease, data on the effect and tolerability of these drugs. The dosage should not exceed 3 tablets per day. Duration of treatment - 5-7 days.
Overdose
In case of overdose is reduced arterial pressure May be respiratory disorders , Manifestations seizures . renal failure , Dysfunction of the gastrointestinal tract.
Overdose is treated symptomatically, but it is forbidden to use antihistamines , and glucocorticosteroids or preparations containing ethacrynic acid .
Cooperation
Fanigan tends to increase the content Digoxin and lithium in serum. Also, while the application, it leads to reduced activity diuretics For this reason, it should be in such situations to control the potassium level in blood when assigning it simultaneously with potassium-sparing diuretics .
While the appointment and Fanigana NSAIDs It increases the likelihood of side effects, so need constant monitoring picture of peripheral blood.
In the context of co-administration with Fanigana anticoagulants It increases the risk of bleeding Hence the need for regular monitoring of the blood coagulation.
Fanigan also greatly enhances the toxic effects on the kidneys cyclosporine .
Terms of sale
Sell a prescription.
Storage conditions
Keep in a dark, dry place at temperatures no higher than 25 °.
Shelf life
3 years.
Analogs Fanigana
Naklofen Duo
Olfen 100
Olfen-75
Neurodiclovit
Nayzilat
Aertal
Indomethacin
Ortofen
Voltaren
Dikloberl
Ketanov
By analogues in Russia include drugs such as: olfen-75 flamidez, oksalgin-dp panoksen, megafen plus diclofenac with paracetamol, pain-healing, diklokain, diklopar, maitharen and several others.
Babies
The drug is contraindicated in children under 14 years.
During pregnancy and lactation
Reception at Fanigana pregnancy and between breast-feeding is strictly prohibited.
Reviews Fanigane
The drug is widely used, so a lot of comments about it. Reviews tablets show that the drug is effective when used correctly, but you need to be careful about the possibility of side effects.
Price Fanigana where to buy
Price Fanigan tablet is relatively low - 12 rubles per blister, which is 4 tablets.
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