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Diazolin It is antihistamine Which can be used systemically. Mebhydrolin Contained in this drug is an antihistamine drugs that block histamine H1 receptors. It significantly reduces the spasmogenic effects of histamine relating to smooth muscles of the intestines, bronchi. It also affects vascular permeability . When comparing the drug with the first-generation antihistamines such as suprastin or diphenhydramine , Its sedative and hypnotic influence is much less pronounced. Diazolin also has anesthetic properties, but they appear weak.
The absorption of the drug is very fast and after only 15-30 minutes it takes effect. The maximum effect is observed in patients after 1-2 hours, while it lasts about two days. Excreted eliminated via the kidneys.
Indications and methods of use of the drug:
The drug has been used successfully for the prevention and treatment of the manifestations of both seasonal and allergic rhinitis. It is also prescribed to patients diazolin hay fever , Urticaria, allergic food and medication. It is administered in the presence of visible skin reactions due to insect bites varied, as well as dermatoses which are accompanied by itching.
The drug tablets and dragees is used after a meal. Children twelve years and adults used means one or two times a day at a dose of 100-200 mg. The maximum single dose for adults should reach 300 mg per day adults can take 600 mg diazolin. Children from five to twelve years of age may receive 50 mg two or three times per day. Children three to five years of age may receive 50 mg 1-3 times a day. How long should treatment last for specialist must determine in each case.
The drug diazolin children used as follows: in a bottle, which contained granules is added with 100 ml of warm boiled water. Content should be very carefully stir for a few minutes. The suspension in doses, which are easily determined using the bundled graded glass is given to children. Dosages should be: 2, 5 ml - children 2-3 years; 5 ml - children 4-6 years; 7, 5 mL - for children 7-10 years. Take the drug must be two or three times after meals over 5-7 days. The suspension is a must shake before use.
Contraindications and possible side effects:
Do not take the drug to patients having a high sensitivity to the diazolin. The drug is not prescribed to people with acute gastric ulcer and duodenal ulcers, and any other inflammatory diseases of the gastrointestinal tract. Contraindications diazolin is pyloristenosis . During dosing can occur following side effects. In work Digestive System : Possible irritation of the gastrointestinal tract, dyspeptic symptoms - nausea, heartburn , Pain in the epigastric region. In work CNS : Dizziness, paresthesia A high level of fatigue, excessive sleepiness, slow response, blurred vision. Also, when taking diazolin may experience dry mouth, problem urinating, the manifestation of allergic reactions. Very rarely granulocytopenia and agranulocytosis . The risk of side effects significantly increases in overdose.
Specific recommendations:
With extreme caution should be prescribed the drug if the patient has severe liver and kidney failure. In this case it is necessary to adjust the dose of the drug alone, and the number of its stages. Not recommended for use during diazolin epilepsy , Angle-closure glaucoma, in a variety of cardiac arrhythmias. It is not recommended to drink alcohol in parallel with the reception of the drug. During pregnancy and during lactation diazolin appointed only if the potential positive effects of the drug, according to experts, will exceed the risks for the future mother and child. Also during the drug treatment is not recommended to drive vehicles and to perform other potentially dangerous activities that require maximum concentration. There are paradoxical reactions during treatment of children: they may experience irritability, insomnia, tremor .
The drug potentiates the sedative effect of sleeping pills and other drugs which depress the central nervous system. The same applies to the effects of alcohol. Store this medication in a dry and dark place at the temperature should not exceed 25 ° C.
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