Okumetil

Description overdue on 09/12/2014

• Latin name: Ocumethyl
• ATC code: S01GA51
• Active substance: Diphenhydramine naphazoline + + Zinc sulfate (Diphenhydramine + Naphazoline + Zinc sulfate)
• Manufacturer: CPC Alexandria, Egypt

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and Pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Okumetila
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• Reviews
• Price, where to buy

Composition

The composition of these eye drops composed of the following active substances:

• Zinc Sulphate   - 10 mg;
• diphenhydramine hydrochloride   - 10 mg;
• nafazolina hydrochloride   -10 Mg.

Excipients: sodium citrate, citric acid, benzalkonium chloride, methylene blue dye, sodium chloride, hypromellose 4000, sodium hydroxide, distilled water.

Product form

Eye drops, 10 ml, 5 ml.

Pharmacological action

Okumetil is a topical drug that is used to treat ophthalmic diseases different nature.

Through its member active substances, the drug helps to reduce swelling century by blocking histamine receptors and effective vasoconstriction. The preparation includes hydrochloride nafazolina , A positive effect on the mucous membrane of the eye, reducing the inflammatory process. Zinc Sulphate   in Okumetile it acts as an antiseptic.

Pharmacodynamics and Pharmacokinetics

Eye drops for topical application Okumetil a combined tool, which consists of three active substances.

Zinc sulphate   when properly used not only exerts an antiseptic, but also anti-inflammatory effect on the tissues.

Naphazoline   structurally related to sympathomimetics, so during regular use of the drug in the treatment of various ophthalmic diseases a decrease in the swelling of tissues and redness of the mucous membrane .

Diphenhydramine   acts by blocking the H1-histamine receptors, thereby preventing swelling of tissues and reducing capillary permeability.

Okumetil indicated for topical application in which it is absorbed. Other information, including the degree of penetration of the active substances in the tissue of the eye drops of the eyesight absent.

Indications

Okumetil Drops is indicated for the treatment of ophthalmic diseases such as:

• chronic nonspecific   conjunctivitis   and   Blepharoconjunctivitis ;
• allergic conjunctivitis   and Blepharoconjunctivitis ;
• angular conjunctivitis .

Also, the drug is prescribed to reduce the symptoms of irritation of the eye tissue. Symptoms expressed strong local tissue redness, itching, and feeling the presence of a foreign body.

Contraindications

The drug Okumetil, despite its apparent simplicity, has a sufficiently large number of contraindications:

• Eye drops Okumetil not be used during the period pregnancy   and Lactation .
• It is not recommended to use eye drops at a hypersensitivity to one of the active substances.
• Drops are contraindicated for children under the age of two years.

Also, experts advise not to use the vehicle under the following conditions:

• closure glaucoma;
• seizures;
• various gastrointestinal diseases;
• syndrome of "dry eye";
• bronchial asthma;
• diseases of the cardiovascular system, including the hypertension ;
• pheochromocytoma;
• thyroid dysfunction;
• atherosclerosis   pronounced etymology;
• diabetes.

Side effects

The most common side effect is a slight application Okumetila burning eyes   after instillation. Also, there is often a short-term blurred vision and a manifestation of a variety of allergic reactions. In humans, the so-called " aphakic eye "(Without the lens) the use of this drug may be associated with the development maculopathy   (defeat of the rear segment of the eye - the central part of the retina, which is called macula ) And appearance central scotoma   (a defect of sight, when in front of the eye "hangs" or dark colored spot). If you notice any of these side effects of the use of eye drops should be stopped, leading to regression of symptoms.

Topical application of eye drops could trigger the development of reactive hyperemia   because part of the drug nafazolina . Furthermore, in a preparation naphazoline can cause swelling of the mucous membranes, increased intraocular pressure and pupil dilation.

Much less use of this drug is:

• high blood pressure;
• tachycardia ;
• nausea;
• Headache ;
• paresis of accommodation   (decreased ability to distinguish small details)
• photosensitization   (hypersensitivity mucosa);
• dry mucous membranes with subsequent numbness;
• drowsiness ;
• a feeling of weakness;
• incoordination;
• dizziness .

Instructions for use Okumetila

Instructions on Okumetil no different complexity. Eye drops should be used twice a day by one drop in each conjunctival sac.

The use of this drug should be discontinued if, within three days of the start of treatment was not positive change.

Overdose

Drug overdose data is unlikely, since systemic absorption of active ingredients of the drug is relatively low.

Interaction with other drugs

There are drugs and drug groups by reaction with a drug Okumetil which has the opposite effect, or the effect of it is neutralized. Among these drugs:

• MAO inhibitors   - Use the eye drops is not recommended, as it may rise blood pressure.
• Drugs with hypertensive effect and it should not be used in conjunction with eye drops, as the hypertensive effect may be enhanced.
• CNS stimulants - Reduce the stimulating effect.
• Local anesthetics are totally incompatible ophthalmic eye drops Okumetil.
• Formulations silver salt - are not compatible for pharmaceutical compositions.
• Citral   - Absolute incompatibility with Okumetilom.
• Ichthyol   - It is also incompatible with the data eye drops.
• Hininsoderzhaschie drugs   - Experts strictly prohibit the use of two drugs at the same time.
• Preparations on the basis of lead - use of these drugs is strictly prohibited, along with these eye drops because of the total incompatibility.

Terms of sale

Buy Okumetil possible in pharmacies without a prescription.

Storage conditions

Storage temperature should not exceed Okumetila room - 15-25S Celsius. Store this medication is recommended in a dark room.

Shelf life

Drops in sealed packaging can be stored up to three years. After the loss of sealing, store the drug may be less than one month.

Analogs Okumetila

Match code ATC 4th level:

• Vizin

It is analogues Okumetila Visine, octyl   and Naphthyzinum . More drugs, similar in composition, the pharmaceutical market is not represented.

Reviews Okumetile

Reviews of eye drops Okumetil are controversial. It is noteworthy that in the specialized forums positive reviews of this drug outweigh neutral. Negative feedback unit, which suggests good effects that have the eye drops in the treatment of various eye diseases.

Price Okumetila

Price Okumetila relatively low - about 150 rubles.

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