Description overdue on 02/06/2014
- Latin name: Imunorix
- ATC code: L03AX05
- Active substance: Pidotimod (Pidotimod)
- Manufacturer: Doppel Farmaceutici (Italy)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Imunoriks (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One vial of the drug, in addition to the main active substance pidotimoda in an amount of 400 mg, containing aids:
- 70% sorbitol - 2500 mg;
- fruit flavoring wild berries - 21 mg;
- sodium metiparagidroksibenzoat - 10.3 mg;
- sodium chloride - 5.6 mg;
- dye anthocyanin - 5.6 g;
- sodium saccharin - 5 mg;
- edetate disodium - 3.5 mg;
- trometamol - Acidity regulator to pH 6.5;
- propyl parahydroxybenzoate Sodium - 1.6 mg;
- carmine dye " Ponceau 4R "- 500 g;
- purified water - up to 7 ml.
Product form
Imunoriks sold in the form of a clear solution of the characteristic red and purple color for oral with berry flavor and a pleasant taste. It is packed in bottles of 7 ml each, 10 pieces.
Pharmacological action
Pidotimod - Immunotropic active ingredient peptide structure, that is getting into the body of pharmacological agents directs its effect on the individual components of the immune system:
- It has a stimulating effect on the cellular mechanisms of protection.
- It strengthens the body's non-specific barriers (increases the production of immunoglobulin class A).
- Increases chemotactic activity .
- Increases synthesis T and B lymphocytes It normalizes the ratio of different fractions of white blood cells.
- Increases efficiency phagocytosis Stimulating interaction and multi-mononuclear phagocytes.
- Activates natural killer cells, enhancing protection against a pair of neoplastic cells and harmful pathogens.
- Largely increases cytokine production (eg, interleukin-2 ) And Gamma-interferon .
Pharmacodynamics and pharmacokinetics
Imunoriks rapidly absorbed from the gastrointestinal tract. Its bioavailability (amount of drug delivered into the systemic circulation without metabolic changes) is 45 percent. Associated with the plasma protein is bad (only 5 percent of the drug is a long-circulating), because such a short half-life - 4 hours.
Imunoriks displayed by the kidneys without undergoing qualitative changes.
Indications
As it has Imunoriks immunomodiluryuschimi properties , It is used in such pathological conditions as:
- Acute diseases of infectious origin (when all the fault of exogenous pathogen) - laryngitis . sinusitis . pharyngitis and so on.
- Defeats bronchopulmonary system.
- In order to strengthen the immune response.
- With diseases of the urinary system bacterial or fungal origin ( nephritis . urethritis . prostatic diseases men).
- In an integrated therapeutic course at immunodeficiency .
- To prevent at frequent infectious diseases .
Contraindications
From Imunoriksa inclusion in the scheme of conservative treatment is to give first of all in case of intolerance or hypersensitivity of the body to the constituent components. Also, do not prescribe the drug pregnant , Mothers who are breastfeeding, children under the age of three years.
With allergic conditions . E syndrome hyperglobulinemia the drug should be used only in a hospital, under the close supervision of qualified medical personnel.
Side effects
Imunoriks well tolerated and has a positive effect on the body with little or no adverse effects. So during all clinical use of the drug were observed only mild allergic reactions ( itching . respiratory reactions . hives and so on).
Instructions on Imunoriks (method and dosage)
Since the drug is available in an oral solution, then it should be taken before a meal, so the efficiency of the biologically active substance will be higher. Adult single dose of 2 bottles (when converted to the primary components - 800 mg pidotimoda ) For children - 1 bottle (400 mg, respectively). Traditionally conservative course of pharmacological treatment of immune disease is 15 days.
However, in severe recurrent respiratory disease or urinary systems, instructions for use Imunoriksa undergoes certain changes. First of all, the reception rate of the pharmaceutical preparation is extended up to 45 or 90 days depending on the severity of the patient's condition. If there is the risk of adverse reaction to the drug should be taken only under the close supervision of a qualified health professional.
Overdose
Pharmacological agents is not peculiar accumulation and self-inductance, because Imunoriksom overdose in clinical practice is not described.
Cooperation
Imunoriks can be safely used with antibiotics different groups to enhance effectiveness against infection of the respiratory system, or urinary tract. Also, there is no pathological effects, if you use the drug with antipyretics .
Do not use Imunoriks against other immunostimulatory or immunosuppressive drugs, in this case, the effect of pharmacological substances becomes almost uncontrollable.
Terms of sale
The drug in the pharmacy dispensed strictly on medical-prescription form.
Storage conditions
The medicine should be stored away from direct sunlight in a dark, dry place that is inaccessible to children. Optimum temperature - not more than 30 degrees Celsius.
Shelf life
3 years from the original packaging.
Cautions
Imunoriks no effect on cognitive function, fine and gross motor, respectively, it can be used before driving or operating technically sophisticated machines.
Analogs Imunoriksa
- Timalin
- TSikloferon
- Uro-Vaks
- Engistol
- Imunofan
- Kipferon
- Tsitovir 3
- Imudon
- Lavomax
- Amiksin
- Immunomax
- Immunal
Analogs Imunoriksu drug loses in strength in most clinical trials, but they are much cheaper that the positive side is clearly their use in the pharmaceutical practice. So in the scheme of conservative treatment could be included immunomodulators , as:
- oral drops Immunal ;
- liquophilic powder for intramuscular injection Immunomax ;
- syrup for internal use Immuno-Tone ;
- pills Imunoplyus .
During pregnancy and lactation
The drug is strictly prohibited for use during critical periods in the life of the expectant mother, but experimental studies using animals showed no teratogenic or embryo-toxic action.
Reviews Imunorikse
Reviews of doctors showed positive effects of using the drug - marked effective increase of the immune response, increased resistance to invasions pathological microorganisms (including rezistenstnost to bacteria, fungi and even viruses), which confirmed the clinical analysis and research.
Positive feedback on Imunoriks children usually marked grateful mothers after prevention of the disease in the spring and winter. After conservative course there is resistance to the typical young body respiratory diseases, increase efficiency while studying. Children older than school age is recommended to use the drug in the spring and summer, so delivery of final examinations is not to wash random pathologies.
Among the adult category of patients the drug has won respect through effective immune when urinary tract diseases . When applied to the STI offices Imunoriksa therapeutic course is reduced by several times, reflecting the positive effect of the drug.
Price Imunoriksa where to buy
The obvious drawback of the drug is its cost - price Imunoriksa in Russia ranges from 700 to 800 rubles depending on the network pharmacy kiosks.
Ukraine Imunoriks children can get some cheaper - for 200 hryvnia. It is much more profitable to book a pharmaceutical preparation through the Internet.
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