Description overdue on 09/16/2014
- Latin name: Erythromycin
- ATC code: D10AF02
- Active substance: Erythromycin (Erythromycin)
- Manufacturer: SYNTHESIS, JSC (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacokinetics and pharmacodynamics
- Indications
- Contraindications
- Side effects
- Instructions for use erythromycin ointment (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
The structure means includes active substance erythromycin And optional ingredients: sodium bisulfite, propyl parahydroxybenzoate, methyl parahydroxybenzoate, anhydrous lanolin, petrolatum.
Product form
Eye ointment eritromitsinovaya can have color from light yellow to brown-yellow, is contained in tubes of 10 g
Pharmacological action
Erythromycin - is antibiotic Which belongs to the group of macrolides. It has on the patient bacteriostatic effects. The drug affects the Gram-positive bacteria (Streptococcus pneumoniae . Staphylococcus spp. . Bacillus anthracis . Streptococcus spp. . Corinebacterium diphtheriae . Clostridium spp. ).
Also, the drug acts on certain Gram-negative microorganisms. However, most gram-negative bacteria as well as fungi, medium and small viruses exhibit resistance to erythromycin.
Patients transferred Erythromycin is better than penicillins . Therefore, the means may be imposed in the case of allergy to penicillin. In the treatment of resistance to it means microorganisms developed relatively quickly.
Pharmacokinetics and pharmacodynamics
Data on the pharmacokinetics and pharmacodynamics not available.
Indications
Erythromycin ointment is used to treat diseases of infectious and inflammatory nature, which were caused by organisms susceptible to erythromycin. It is used in the treatment of infectious and inflammatory diseases, which were triggered by pathogens, resist tetracyclines . chloramphenicol . penicillin . streptomycin .
Externally used to treat youth blackheads .
Displaying the topical application of drugs in infectious and inflammatory diseases of the eye.
Also, erythromycin ointment is indicated for treatment of trachoma, inflammation of the mucous membranes of the eyes, for the treatment of pustular disease of the skin, pressure sores infected wounds, burns, trophic ulcers.
Contraindications
Defines the following contraindications:
- abnormal liver function;
- jaundice history;
- a high level of sensitivity to macrolides.
Side effects
In the treatment of erythromycin ointment can develop the following side effects:
- irritant, provoking itching, redness;
- other allergic reactions ;
- disorders of the digestive system: nausea, vomiting, diarrhea, goiter, etc .;
- candidiasis ;
- tinnitus and hearing loss;
- tachycardia .
Prolonged treatment may develop secondary infection, which was triggered by micro-organisms that are resistant to erythromycin .
Instructions for use erythromycin ointment (method and dosage)
Instructions on erythromycin ointment provides that before prescribing the drug should determine the level of sensitivity to the ointment of the microflora, which provoked the disease. Eye ointment for a lower or upper eyelid three times a day, and its number is 0, 2-0, 3 g If the patient is diagnosed with trachoma, mortgage means you need 4-5 times a day.
Instructions for use erythromycin ointment shows that the duration of treatment depends on the severity of the disease and treatment. In most cases, the treatment lasts from half to two months. When trachoma treatment increases up to 4 months.
With skin diseases the drug should be applied to the affected area 2-3 times daily. During treatment of burns Drugs used 2-3 times a week. The tool should be applied thinly enough, treatment can last from 3-4 days to two weeks.
Change the course of treatment or dosage your doctor may individually depending on the diagnosis and characteristics of the disease.
Overdose
No data on the effects of an overdose of erythromycin ointment.
Cooperation
If erythromycin is used in conjunction with Aminophylline . caffeine . Theophylline , The plasma concentration of the latter increases. As a consequence, it increases the risk of toxic effects.
Erythromycin increases the concentration cyclosporine in the blood, thus increasing the probability of nephrotoxicity.
Medications that block tubular secretion, increase the half-life of erythromycin.
The antibiotics erythromycin number does not coincide with the Clindamycin . Lincomycin . Chloramphenicol . Under the influence of erythromycin decreases the bactericidal effect beta lactam antibiotics .
Simultaneous treatment with erythromycin and Theophylline It raises the level of the latter.
If carried out simultaneous treatment with erythromycin and means of metabolism that occurs in the liver, the concentration of these agents in blood plasma may increase.
Erythromycin reduces efficiency hormonal contraceptives .
Concurrent use of erythromycin ointment and abrasive substances that irritate the skin or provide exfoliation, leading to the appearance of drying irritating effect.
Terms of sale
Ointment without prescription.
Storage conditions
Ointment should be stored at room temperature in a dry place, keep away from children.
Shelf life
Store can be 3 years after the expiration of the period of validity can not be used.
Cautions
After applying Erythromycin before using another external means of acne must be at least one hour.
Unless acne It does not decrease after 3-4 weeks of regular use of ointment, it is necessary to consult a specialist. In some cases, a pronounced effect was observed only after 2-3 months of application of ointment.
If the product is used for a long time may develop superinfection.
If eye ointment is used for the prevention of neonatal ophthalmia It should not be washed out of the eye.
For children Whose mothers diagnosed and expressed gonorrhea Erythromycin as an ophthalmic drug is prescribed concurrently with an aqueous solution penicillin G (parenteral administration).
Analogs
Klindovit
Erythromycin
Zinerit
Analogs erythromycin ointment - is Tetracycline ointment , Preparations Tsiploks . Dexa-Gentamicin . Tobradeks .
Babies
It is used to treat children with the need to adhere strictly to the scheduled dosage and treatment regimens.
During pregnancy and lactation
Erythromycin is able to cross the placenta, it is also excreted in breast milk. With pregnancy the doctor should clearly match the level of the anticipated benefits and risks.
Lactation at the time of treatment is better to stop.
Reviews of erythromycin ointment
Online there are numerous reviews erythromycin ointment, which usually involves the use of remedies for acne. It is noted that this medication is helping get rid of acne effectively, preventing the effects of bacteria.
However, there are reviews, which noted that erythromycin ointment after prolonged use has not had the expected impact. Doctors focus on that to apply ointment for the treatment of acne and other diseases is necessary for a clear pattern, and only after consultation with a specialist. Since the drug is an antibiotic, its use should be treated intelligently.
Price erythromycin ointment, where to buy
Price erythromycin ointment is from 20 to 40 rubles per pack '15
In Ukraine, the price of eye ointment is an average of 30 hryvnia per package in '15
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