Description overdue on 08/26/2014
- Latin name: Stopdiar
- ATC code: A07AX03
- Active substance: Nifuroxazide (Nifuroxazide)
- Manufacturer: Gedeon Richter (Hungary)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Stopdiara
- Contraindications
- Side effects
- Instructions for use Stopdiara
- Cooperation
- With alcohol
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Enterofuril or Stopdiar - which is better?
- Reviews
- Price, where to buy
Medicine Stopdiar - composition
Tablets are film coated. The composition of one tablet are:
- active substance nifuroxazide 100 mg;
- Excipients: talc . colloidal silica . potato starch . gelatin . magnesium stearate ;
- film coating composition: talc . Valium . titanium dioxide . polyethylene glycol 20000 . quinoline yellow dye .
Oral suspension in 5 ml suspension contains:
- active substance nifuroxazide 220 mg;
- Excipients: Carbomer . saccharose . sodium hydroxide . citric acid monohydrate . 30% simethicone emulsion antifoaming . methyl parahydroxybenzoate . Banana flavor .
Product form
Pills in A film coated yellow color, round, convex with both sides. 24 tablets are in a blister pack, placed in a cardboard box.
Oral suspension light lemon color, odor banana in dark glass bottles of 125 ml (suspension in 90 ml vial). The vial is placed in a cardboard box, there is a double (at both ends) measuring spoons 5 and 2, 5 ml.
Pharmacological action
The drug has antibacterial effect in relation to the causative agents of intestinal infection.
Pharmacodynamics and pharmacokinetics
The active substance Stopdiara nifuroxazide It refers to the group of nitrofurans and ingestion exerts an antibacterial effect on pathogenic and opportunistic microorganisms that cause intestinal infections. Nifuroxazide active against gram-positive ( staphylococci, streptococci ) And Gram-negative ( Salmonella . Shigella . Klebsiella . E. coli ) Bacteria, which often are the causative agents of intestinal infections.
Stopdiara action due to the suppression action of enzymes involved in cellular metabolism pathogens. Due to the metabolic break down the cell membranes of bacteria and cells die.
Activity Stopdiara against the infectious agent is not reduced even during prolonged treatment. However, he does not destroy the intestinal microflora, so after his application for restoration of the digestion process takes less time than with the use of antibiotics. Effect of the drug independent of pH in the intestines.
After ingestion of capsules or suspensions of the active ingredient is practically not absorbed in the intestine, not into the blood stream and has no systemic effects on the body. It operates directly in the intestine, and then excreted naturally by the faeces.
Indications Stopdiara
The drug is prescribed in the following diseases:
- acute intestinal infections , Caused by susceptible to nifuroxazide causative agents of;
- chronic bowel disease ( enteritis and enterocolitis ) An infectious nature.
Contraindications for use Stopdiara
Contraindications to the use of the tablets:
- allergies to medications from the group of 5-nitrofuran ;
- A hypersensibility of the organism to other components of the drug;
- the age of six.
Contraindications to the use of the suspension:
- allergies to medications from the group of 5-nitrofuran ;
- hypersensitivity to other components of the drug;
- the age of two months;
- prematurity.
Precautions are advised to take the medication at the time of pregnancy and breast-feeding child as clinical tests on these categories of patients was conducted.
Side effects Stopdiara
The drug is usually is well tolerated by all patients and only in single instances are manifested its side steps:
- The stomach and intestine - May appear transient abdominal pain, nausea, diarrhea symptoms intensify; it does not require interruption of treatment;
- allergic reactions - hives . angioedema , Respiratory disorders. In such circumstances you should immediately stop taking the drug.
Instructions for use Stopdiara
Instructions on pills Stopdiar Tablets are swallowed without chewing and drinking water every 6 hours. Stopdiara reception does not depend on the power mode. Adults and children after six years should take 200 mg (2 tablets) four times a day for a week.
Instructions on Stopdiar - suspension for children : Suspension give the child every 6 - 8 hours, without associating it with feeding; the vial before applying carefully is shaken, achieving homogeneity a suspension of, after which is dosed the suspension was with the help of dimensional spoons of (1 small dimensional spoon on 2.5 mL contains 110 mg of the drug, 1 large dimensional spoon on 5 ml of - 220 mg). Guide for Children recommends the following age dosage of the drug:
- 2 - 6 months: 110 - 220 mg of (1-2 scoops 2.5 ml) twice per day;
- 6 months - 6 years: 220 mg (1 measuring spoon on 5 ml) thrice per day;
- 6 - 18 years and adults: 220 mg (1 scoop 5 ml) four times a day.
Duration of use Stopdiar suspension for children It should not exceed one week. Treatment should be under medical supervision, because the intestinal infection, especially in young children, often leads to dehydration and related serious complications. Therefore, a constantly replenish lost fluids.
Stopdiara Interaction with other drugs
The drug is practically not absorbed in the intestine and enters the blood, so it can not interact with any other drugs. But if at the same time with Stopdiarom ingest some other drug Stopdiar adsorbs it on its surface and bring the body. Therefore Stopdiara between ingestion and other drugs should be a break 2 - 3 hours.
Interaction with alcohol
During treatment Stopdiarom not take alcoholic drinks, since the reception of the drug greatly increases the body's sensitivity to alcohol. Even if accidentally eating small amounts of alcohol may develop severe teturamopodobnoy reaction : A patient is sharply reduced arterial pressure Appear nausea, vomiting Sometimes loss of consciousness and seizures.
Terms of sale
The preparation is available on medical prescription.
Storage conditions
The tablets were stored in a dry, dark place at a temperature of 15-25 ° C. The suspension should be stored at a temperature not exceeding 25 ° C. Medications should be available for children.
Shelf life
Shelf life Tablets - 4 years, the suspension - 3 years.
Analogs Stopdiara
Ersefuril
Nifuroxazide
Entoban
Analogs - a variety of dosage formulations groups which are used to treat the same disease. The analogue of Stopdiara is a Furazolidone - Preparation of nitrofurans group, but with a different active ingredient. Furazolidone - it is one of the first products from the group of nitrofurans, who were appointed in the treatment of intestinal infections. Its efficiency is definitely lower than Stopdiara.
Synonyms are drug Enterofuril, ersefuril, Diastat, nifuroxazide . All these medicines active substance is nifuroxazide.
Enterofuril or Stopdiar - which is better?
This is absolutely identical preparations, which have a one and the same active substance, are issued in identical dosage forms for adults and children, have identical indications and contraindications for the application of.
Both drugs let out pharmaceutical companies with a good reputation: Stopdiar - Gedeon Richter (Hungary) Enterofuril - Bosnalek (Bosnia and Herzegovina).
Reviews Stopdiare
Reviews Only about tablets positive . Produced the drug in a convenient dosage form, effectively interrupts the majority of intestinal infections, has virtually no side effects and contraindications for use.
The suspension Stopdiar reviews also has a purely positive. This drug from an intestinal infection for children is widely used in outpatient practice and hospital.
Price Stopdiara
The price of one pack of pills Stopdiar in Moscow varies from 128 to 158 rubles;
Suspensions Stopdiar price from 214 to 247 rubles.
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