Lomilan

Description overdue on 09/26/2014

• Latin name: Lomilan
• ATC code: R06AX13
• Active substance: Loratadine (Loratadine)
• Manufacturer: LEK d.d., Slovenia

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Lomilana (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Babies
• Reviews
• Price, where to buy

Composition

AT tablets   contains 10 mg loratadine As auxiliaries used corn starch, lactose, magnesium stearate, pregelatinized starch.

As a part of suspension loratadine   1 mg, including excipients - White sugar, concentrated glycerol, magnesium stearate, sodium citrate dihydrate, purified water, Polysorbate 80, Avicel RC 591 FMC, sodium citrate dihydrate, wild cherry flavor, citric acid monohydrate, propylene glycol, sodium benzoate.

Product form

Lomilan available as tablets   and suspension .

• White 10 mg tablets have a flat shape, on the one hand and the notch chamfer located. The cardboard pack is 1, 2 or 3 blisters to 7 or 10 tablets each.
• The homogeneous suspension is white. The cardboard packaging is made of dark glass bottle of 120 ml, and the dosage spoon.

Pharmacological action

Infectives for systemic use blocks histamine H1-receptor. It has antiexudative, antipruritic and antiallergic effects.

Pharmacodynamics and pharmacokinetics

Lomilan reduces capillary permeability, relieve spasms of smooth muscles, prevent the development of edema. The drug has antiexudative effect   erythematous and helps reduce symptoms. Half an hour after receiving Lomilana develops antiallergic effect, reaching its maximum at an average of 8-12 hours. The duration of effect - 24 hours.

The drug has no effect on the central nervous system and ECG readings, as it does not cause addiction. Do not use Lomilan to assist in the event of a serious allergic reaction, as the effect of its application is developed to an hour.

After receiving the drug is completely absorbed from the gastrointestinal tract. Slower absorption is the presence of food. The maximum serum concentration reached within one hour. Lomilan metabolized in the liver, forming an active metabolite descarboethoxyloratadine .

The half-life is on average 8 hours increases with alcoholism   and in the elderly. Excreted by the kidneys and the bile.

Pharmacokinetics virtually unchanged in the case of chronic renal failure in a patient and during hemodialysis.

Indications

The drug Lomilan has the following indications:

• pseudoallergy reaction;
• allergic conjunctivitis ;
• nasal allergy ;
• reactions to insect stings;
• allergic skin disease, including chronic idiopathic urticaria .

Contraindications

The drug is not administered in the following cases:

• galactose malabsorption glucose- ;
• children under two years (suspension), up to three years (tablets);
• lactase deficiency ;
• during pregnancy and lactation;
• lactose intolerance ;
• Hypersensitivity to Loratadine   or any other component.

With careful preparation is indicated for hepatic and renal failure .

Side effects

Receiving medicament may be accompanied by the following phenomena:

• anaphylactic reactions ;
• nervous irritability, drowsiness , Fatigue, headache . dizziness   and insomnia ;
• syncope, tachycardia . arrhythmia , Palpitations;
• gastritis , Increased appetite, dry mouth, nausea;
• abnormal liver function;
• allergic reactions in the form of rash . alopecia .

In addition to these effects in children may develop sedation .

Instructions for use Lomilana (method and dosage)

Tablets Lomilan, instructions for use

Inside, it can be received at the same time food is allowed to chew the tablet in the presence of necessity. To wash down with milk or water should be.

Adults and children over 12 years old should take one tablet per day (10 mg), children aged 2-12 years of age with a weight greater than 30 kg - 10 mg knocks (1 tablet), weighing less than 30 kg - 5 mg per day ( poltabletki).

The suspension

Recommended Lomilan taken as a suspension for children up to 12 years.
Ingested orally, possibly in conjunction with food, drinking water or milk.
Adults and children over 12 years, as well as children aged 2-12 years of age with a weight over 30 kg is recommended to take once a day 10 ml (two dosing spoon), weighing less than 30 kg - 5 ml (one dosing spoon).

Special groups of patients

Patients with impaired liver function is assigned to a smaller dose of the drug: adults and children (with a weight greater than 30 kg) - 10 ml or 10 mg per day. The treatment period depends on the duration of symptoms of disease. If the status of the patient for 3 days did not improve, then the drug should be considered ineffective.

The dosage to patients with renal impairment and the elderly are not adjusted.

The initial dose for patients with kidney failure are as follows: children from 6 years and adults - 10 mg a day, fly to 3 years - 5 mg every other day.

Overdose

Symptoms of overdose: headache . drowsiness , Palpitations, lasting a long time. While taking the drug excess doses should wash out the stomach, cause an artificial vomiting, take the absorbent (eg, Activated carbon ).

To this drug is no specific antidote. With hemodialysis is not displayed. No information for the moment, whether the vehicle is derived using peritoneal dialysis. After providing the necessary assistance should be a specific time to monitor the patient.

If symptoms of the nervous system or the heart is necessary to address to experts.

Cooperation

Together with the admission inductors makrosomalnogo oxidation ( barbiturates . tricyclic antidepressants . ethanol . Rifampicin . phenytoin ) Decreases the effectiveness of loratadine.

Reducing the concentration of drug in the blood can cause its interaction with erythromycin . quinidine . Fluoxetine . Ketoconazole . Itraconazole . This can result in increased side effects from taking the drug.

Terms of sale

The drug is intended for non-prescription.

Storage conditions

Lomilan in suspension and in the form of tablets should be stored at temperatures up to 25 ° C.

Shelf life

4 years.

Cautions

It is recommended to stop taking the drug for at least 2 days prior to removal of skin allergy tests, as Lomilan may affect the results.

While driving patients taking Lomilan should be cautious as possible of side effects.

Babies

Yes, currently there is insufficient data on the efficacy of the drug and its safety for children up to 2 years.

Reviews

Reviews Lomilane indicate that the drug really good relieves swelling and allergic reactions. In general note and good tolerability of the drug. The downside, some buyers believe that the effect of the drug becomes noticeable only an hour after his admission. Some also mention the occurrence of side effects such as irritability and nervousness in children.

Price Lomilana where to buy

Moscow value slurry (120 ml) is from 91 to 125 rubles.

Price Lomilan tablets: pack of 10. is from 143 to 164 rubles., 7 pcs. - From 105 to 118 rubles.

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