Vinpocetine

Description overdue on 15-05-2012

Related Articles:

• Iodine
• How to take aspirin for the prevention of cardio?
• The price of the ampoule Panavir
• Instructions for use sulfadimetoksin

Tweet

Vasodilators cerebral vessels. The medicament improves cerebral blood flow Expands the lumen of blood vessels of the brain, causing a weakly expressed fall in systemic blood pressure, improves the process of glucose and oxygen to the brain, increases blood flow. Under the influence of the drug increases the stability of brain cells to hypoxia, improves the transport of substrates of energy supply and oxygen to the tissues is enhanced metabolism. Vinpocetine promotes accumulation of ATP, cAMP in the tissues increases the level of catecholamines in the brain tissue. Vasodilating effect   It provided a direct relaxing effect of the active ingredient in the smooth muscles of the vessel walls. Drugs do not change the blood flow in intact areas, improves blood flow to the affected, ischemic areas, does not cause the phenomenon of "steal." By reducing platelet aggregation, increase erythrocyte deformability, decreased blood viscosity improving processes microcirculation . Vinpocetine is available as a solution, a concentrate pellets.

Indications:

Vinpocetine is prescribed for cerebrovascular disorders (acute and chronic), after a stroke, at the completion of a stroke, progressive stroke, mental and neurological disorders in patients with cerebrovascular disease ( headache . memory impairment . disorders of the motor system . dizziness . apraxia . aphasia ). The drug is effective in posttraumatic, hypertensive encephalopathy. In menopause Vinpocetine vasovegetative prescribed for symptoms. The drug is used in degenerative diseases of the macula, choroid, retina, secondary glaucoma, partial occlusion of the arteries in the cochleovestibular neuritis , Meniere's disease, age-related hearing loss, tinnitus, hearing loss and toxic vascular origin, vertigo labyrinthine origin.

Contraindications:

Vinpocetine does not prescribe breastfeeding, hypersensitive to the components, pregnancy. In severe arrhythmias, ischemic heart disease the drug is prescribed with caution. In the treatment of hemorrhagic stroke can be administered parenterally Vinpocetine only after decrease in acute period of 5-7 days.

Side effects, overdose:

The drop in blood pressure. Rarely recorded slowdown intraventricular conduction , Arrythmia, tachycardia. For parenteral administration, marked dizziness, thrombophlebitis , Nausea, flushing of the facial skin, feeling the heat. In case of overdose of vinpocetine is necessary gastric lavage, the appointment of enterosorbents holding posindromnoy therapy.

Mode of application:

Vinpocetine is recommended to be administered intravenously in the acute phase zaboelvaniya. The initial dose - 20 mg per day (dissolved in 0, 5-1 liter infusion solution). In the absence of significant side effects, the dosage was increased to 1 mg / kg / day for 3 to 4 days. The duration of treatment is 10-14 days. While improving Vinpocetine moving to a reception inside three times a day for 5-10 mg. Dosage maintenance therapy is 5 mg three times a day. Drug withdrawal is carried out gradually.

Special instructions:

Patients with diabetes   by parenteral administration requires monitoring of blood glucose as a drug solution contained sorbitol . Vinpocetine is unacceptable intravenous infusion in patients with cardiac disorders because of the risk of ventricular fibrillation, arrhythmias.

Drug Interactions:

During the   Heparin   Vinpocetine increases the risk of bleeding complications. The drug solution for injection is not compatible with the heparin in the pharmaceutical level.