Description overdue on 05/06/2014
- Latin name: Pimafucin
- ATC code: A07AA03
- Active substance: Natamycin (Natamycin)
- Manufacturer: Temmler Italia, S.r.L, Italy
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use pimafutsin (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
Part Candles included natamycin As an active ingredient. Among the additional components: cetyl alcohol . adipic acid , Tallow, sorbitan trioleate Polysorbate 80, sodium.
Ointment Pifamutsin . The main component - natamycin . Auxiliary ingredients: propylene glycol, alcohol tsetostearinovy, lauripsulfat sodium, purified water, detsiloletat, methyl parahydroxybenzoate, cetyl ester wax, propilaparagidroksibenzoat.
Tablets Pifamutsin . The active ingredient in the tablets is natamycin Auxiliary ingredients: kaolin, white beeswax, polyvinyl pyrrolidone, titanium dioxide, sucrose, magnesium stearate, kaolin, methyl parahydroxybenzoate, gelatin, acacia gum, potato starch, calcium carbonate, lactose, triacetin.
Product form
The drug is available in three forms: pills, cream and suppositories vaginal thrush. White round tablets are available in bottles of dark glass, 20 pcs. The cream has a white or light yellow color, is made of aluminum or plastic tubes of 30 g Suppositories are produced in strips of foil, in which the three candles in the package can be 1 or 2 strips.
Pharmacological action
Pimafucin has antifungal and fungicidal activity .
Pharmacodynamics and pharmacokinetics
Principle effects of the drug based on the binding of sterols in the cell membrane, disrupting the integrity that causes the death of the microorganism. The drug affects the yeast-like fungi (especially Candida albicans ) yeast . dermatophytes . pathogenic fungi .
Natamycin is active when local use, the system does not have, it is not absorbed through the skin or mucous membranes. Enteric coating pellets causes the effect of the drug in the intestine.
Indications
Pimafucin cream prescribed for fungal infections nail plates, skin and from lizistyh shells, including vulvovaginitises . balanoposthitis . vulvity . vaginitis . ringworm . otitis Caused by fungi or complicated by candidiasis, candidiasis of nails . skin .
Pimafucin tablets effective in fungal diseases external auditory meatus, the mucous membranes of the oral cavity. It is prescribed for intestinal candidiasis After treatment Corticosteroid . antibiotics . cytostatics . vulvovaginitah . vulvity . vaginitis , Acute atrophic or psevdomembranoznom candidiasis from cachexia .
Candles Pimafucin prescribed for balanoposthitis . vulvovaginitah . vulvity . vaginitis Caused by fungi Candida.
Contraindications
If you are sensitive to the substances included in the pimafutsin, the drug is contraindicated.
Side effects
Tablets early in therapy may cause nausea or diarrhea During further treatment of these symptoms are eliminated spontaneously.
The local application (cream or suppositories) may be slight irritation of the skin or burning .
Instructions for use pimafutsin (method and dosage)
Candles Pimafucin, instructions for use . Used vaginally. With vulvovaginal . vulvitis and vaginitis introduced on 1 candle 3-6 days. Enter must be in position " lying "Maximally deep bedtime 1 time per day. If treatment caused Candida albicans vaginitis It does not help, you should take the tablets - 10-20 days 1 tablet four times a day. Men use a cream during treatment. Duration of treatment is determined individually in each case. Once symptoms disappear, it should be a few more days to continue treatment.
Instructions on cream . It is used topically. In the affected areas from one to several times a day cream should be applied when balanoposthitis . vulvovaginal and vulvitis . If symptoms persist, appointed suppositories or tablets. With ringworm (including diaper rash in children candidosis and skin and nails), the suspension should be applied to the skin and nails to 4 times per day.
With avium external auditory canal lubricated cream affected area should be a day to four times, after cleaning her ear. After the application, must be placed in the ear canal turunda of cotton or wool. The duration of treatment is determined individually. Once the symptoms disappear completely, you need a few days do not stop treatment.
Instructions for use of tablets . Adults with intestinal candidiasis 1 tablet four times a day for children - one tablet twice a day. The average treatment lasts a week.
Overdose
No cases of overdose is not currently known.
Cooperation
Not described.
Terms of sale
Allow the sale without prescription.
Storage conditions
At a temperature of about 25 ° C.
Shelf life
24 months.
Cautions
Under the influence of body temperature suppositories dissolve rapidly, forming a foamy mass, whereby the active substance is distributed evenly. When recurrent or chronic therapy of infection can be supplemented with cream or tablets.
Cetyl alcohol, which is part of suppositories may cause the appearance of a burning sensation in the genital area. It should stop therapy candles during menstruation. During treatment, candles can not exclude sex. However, both partners should be evaluated, and identify lesions Pimafucin use the cream for men. Treatment ointment for men takes place in the manner prescribed in the Regulations. When sexual intercourse during treatment should use barrier contraceptives.
Perhaps the appointment pimafutsin newborn.
Analogs pimafutsin
Alpha Normiks
Nystatin
Analogs Tablets: preparations Alpha Normiks and Nystatin-Health .
Analogs in the form of suppositories: Nystatin . Livarol . Clotrimazole . Price analogues candles - from 37 to 320 rubles.
In pimafutsin analogue cheaper - Nystatin , Domestic production of the drug, similar in action.
Clotrimazole or Pimafucin - which is better?
Clotrimazole comes in the form of suppositories and creams. The course of treatment is usually about a week, the drug was well tolerated, which reduces the risk of side effects to a minimum. However, it may cause an allergic reaction to any of the constituent components. Upon detection of the disease in women who use an ointment from yeast to man. According to experts, Pimafucin more effective at the local use and it hardly reaches the systemic circulation. Therefore, it can be used to treat pregnant women.
Is it better or Terzhinan Pimafucin?
Terzhinan is produced in the form of vaginal tablets, it may appoint not only the presence of the disease, but also for its prevention. The average duration of drug treatment is 10 days. It is also easy to carry, it can be used before the birth.
With alcohol
Alcohol in combination with pimafutsin can lead to consequences, undesirable for the body. It is strictly forbidden to drink alcohol during intestinal candidiasis. Alcohol leads to an exacerbation of fungal diseases that can cause prolongation of the treatment or its inefficiency.
Pimafucin during pregnancy and lactation
There are no contraindications with respect to administration of the drug for pregnant and breastfeeding. Used pills, cream and candles from yeast as early pregnancy, and in the later stages. The most frequently prescribed during pregnancy Pimafutsin candle and not other forms of this drug. The drug is not toxic and is safe for both the fetus during trimester 1 and 2 trimester and during lactation. However, to minimize the risk, it is better to take a candle during lactation, or cream. Use of the drug - as indicated in the instructions.
Reviews pimafutsin
The forums are the vast majority of patients after the use of drugs note a positive effect. However, there are cases when improvement is not observed or is even getting worse. There is also a claim to the short-term effect of treatment for thrush and other diseases.
Pifamutsin from thrush , According to the patients, it helps, quickly eliminating the symptoms. And the cream is effective for both women and men. Tablets Pimafutsin thrush and also help in the treatment and for the prevention of candidiasis.
Reviews of tablets mostly good, the patient wrote a quick and effective action of the drug and the complete absence of side effects. Reviews for candles Pimafucin thrush report that they quickly relieve itching, than with the pill, as are local. Negative reviews cream Pimafucin not, he is very good for fungal diseases and can be easily transferred. Most often the ointment prescribed to men. Positive feedback during pregnancy noted that the tool does not affect the development of the fetus and is very well tolerated, quickly eliminating the disease.
Price pimafutsin where to buy
Cost cream Pimafucin Ukraine is 87 UAH., in particular in Kharkov ointment is - about 81 USD.
In Russia, the price tablets Pimafucin - 360 rubles in Belarus cost medicines in tablets - 133, 5 thousand. Rubles.
Cost candles Pimafucin thrush - 270-380 rubles. In Odessa, the number 3 candles are 123 UAH., Candle number 6 - 213 UAH.
Clarify how much are candles, and buy other forms of the drug can be directly in the pharmacy.
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