Fluoxetine

Description overdue on 11.08.2012

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Antidepressant.   The active ingredient is a selective inhibitor of the reuptake Serotonin . The drug eliminates dysphoria Decreases anxiety, tension, anxiety It improves mood. The drug no sedative effect, does not cause orthostatic hypotension , Nekardiotoksichen. Long-lasting results from the use of observed after 2 weeks of treatment. Fluoxetine is available in capsule form.

Indications:

Fluoxetine is prescribed for depression (mild, moderate, severe flow) with obsessive-compulsive disorder, alcoholism, anorexia, bulimia.

Contraindications:

Fluoxetine does not apply to pregnancy , Simultaneous treatment MAO inhibitors, with suicidal tendencies, severe renal failure, the system, the main component of intolerance, chronic renal failure, breast-feeding. In Parkinson's disease, cachexia, epilepsy, epileptic syndrome of various origin, diabetes , Renal disease medication prescribed with caution.

Side effects, overdose:

Nervous system:   weakness, tremor, asthenia, fatigue, headaches, dizziness, mania or hypomania, suicidal tendencies (especially in patients with depressed mood). The digestive tract:   diarrhea, nausea, hyperptyalism , Dry mouth, reduced appetite. Possible allergic reaction in response to the intake of the drug fluoxetine. It is also noted vomiting, spasms, agitation, nausea. At higher doses recommended the appointment enterosorbents holding posindromnoy therapy administration tranquilizers , Anxiolytics in the development of seizures.

Mode of application:

Fluoxetine depression administered 1 time per day to 20 mg. If necessary, the dosage increase is performed 1 time per week at 20 mg per day. The daily dose - not more than 80 mg (payment for 2-3 hours). Older patients, as well as bulimia fluoxetine administered three times a day, 60 mg / day. With obsessive-compulsive disorder patients receiving recommended 20-60mg / day. The duration of therapy is designed to month. Supportive therapy of 20 mg per day.

Special instructions:

Patients with underweight possible progressive weight loss due anoreksigennogo influence   Fluoxetine medicament. In patients with diabetes registered at the abolition of the drug hyperglycemia On therapy - hypoglycemia. This effect requires correction dosing regimen hypoglycemic agents. Patients should be under a doctor's supervision until improvement. The drug fluoxetine affects the driving of motor vehicles, perform potentially dangerous activities. Invalid intake of ethanol. The elderly, with severe renal pathology of medication therapy should start with half the recommended dose. The interval between the start of treatment and the end of reception of MAO inhibitors should be at least 2 weeks.

Drug Interactions:

Fluoxetine enhances effect of ethanol, alprazolam, hypoglycemic medications, diazepam. The drug increases the concentration of maprotiline,   tricyclic antidepressants , Trazodone, phenytoin 2 times. At the same time taking tricyclic antidepressants require reducing their dosage in 2 times. Anticonvulsant therapy can trigger the formation of long epipripadkov. MAO inhibitors increases the risk of serotonin syndrome: delirium, vegetative lability, myoclonus, sweating, agitation,   dystaxia , Diarrhea, hyperreflexia, tremor of the extremities, chills, hyperthermia, coma. Drugs that enhance the depressing effect on the nervous system, increase the severity of side effects. Admission digitoksina,   anticoagulants   can cause adverse effects by increasing the concentration of unbound, free drug in plasma.