Reglan

Description overdue on 23.03.2012

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Antiemetics . The active component is   metoclopramide . The main ingredient is a blocker of serotonin and dopamine receptors. Reglan fixes hiccups . heartburn , Accelerates gastric emptying, tones lower esophageal sphincter, and slows considerably reduces the motor activity of the esophagus does not cause diarrhea, accelerates the movement of food through the small intestine. The drug stimulates the release prolactin . Available as a solution, tablet.

Indications:

Reglan is prescribed for hiccups, vomiting, hypotension, and atony of the intestine, stomach, when reflux esophagitis , Biliary dyskinesia, exacerbation of ulcerative lesions of the digestive system, flatulence. To enhance peristalsis   the drug is used during X-ray contrast studies of the digestive tract.

Contraindications:

Reglan is not indicated for bleeding in the digestive system, in case of intolerance metoclopramide, pheochromocytoma , The stomach and bowel perforation, mechanical ileus,   pyloric stenosis   stomach, epilepsy, extrapyramidal disorders, if prolaktinzavisimyh tumors. Reglan is contraindicated in pregnancy. In Parkinson's disease, hypertension, asthma, kidney disease, liver and pediatric administered with caution.

Side effect:

Reglan can cause diarrhea . constipation , Drowsiness, dizziness, dry mouth, depression. Long-term use of high doses of the elderly causing gynecomastia dyskinesia , Symptoms of parkinsonism, galaktoreyu. In overdose recorded extrapyramidal disorder . disorientation , Hypersomnia. After the abolition of the drug a day after the symptoms disappear.

Mode of application:

Reglan prniimayut inside for 30 minutes before meals three times a day at 5-10mg. The tablet is recommended to drink a large amount of liquid. The maximum daily dose of 60 mg, 20 mg single.

Special instructions:

In some cases it is recommended to use additional antiparkinsonian agent, central holinoblokatory . It is unacceptable to use ethanol in the treatment of drug Reglan. The drug affects the performance of complex activities, driving.

Drug Interactions:

Anticholinesterase drugs weaken the effect of metoclopramide. Reglan increases exhaustion paracetamol, ampicillin, tetracycline, ethanol, levodopa , Ascorbic acid. The drug reduces the absorption of cimetidine, digoxin. It is unacceptable simultaneous appointment neuroleptics   (increases the risk of extrapyramidal disorders).