Description overdue on 21/10/2014
- Latin name: Anvifen
- ATC code: N05BX
- Active substance: Aminofenilmaslyanaya acid (Aminophenylbutyric acid)
- Manufacturer: AnviLab (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Anvifen, instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
The chemical composition Anvifena capsule contains 25, 50, 125 or 250 milligrams aminofenilmaslyanoy hydrochloride acid As well as auxiliary compounds present: laktoloza, magnesium stearate, and colloidal giproloza silicon dioxide.
In addition, in a gelatin capsule shell may be present (depending on dosage) compounds such as: water, titanium dioxide, gelatin, E133 brilliant blue dye, quinoline yellow E104, E122 and azorubin.
Product form
Anvifen produced in the form of hard gelatin capsules:
- 25 mg., White (№3 size);
- 50 mg., A white body and cap blue shade (size №3);
- 125 mg., Body white, and shades of blue lid (size №2);
- 250 mg., A white body and cap of dark blue color (size №0).
Inside the capsule is a mixture of powder or granules yellow or pure white color.
Pharmacological action
Anvifen has nootropic, antiplatelet, anti-oxidant, tranquilizing , and anticonvulsant effects on the human body.
Pharmacodynamics and pharmacokinetics
How nootropic drug , Facilitates the transmission mediated Anvifen GABA nerve impulses and providing in combination with Activate the tranquilizing effects on the human body. Preparation improves brain function, since influences bloodstream and normalization metabolic processes. Anvifen reduces vascular resistance in the brain, enhances the linear velocity and volume as well as due to its antiplatelet properties improves microcirculation.
The drug has an effect on the severity and shortens nystagmus and increases latent period. It should be noted that the drug has absolutely no influence on the adrenergic and cholinergic receptors . In applying Anvifena disappear headache Normalized dream Disappears irritability and heaviness Patients become emotional lability. After a course of treatment with increased mental and physical activity, increases motivation is not increased excitability or Sedation .
It is worth noting that this drug does not inhibit CNS even in the treatment of elderly patients. After entering the human body active substance is rapidly distributed in tissues and metabolized 95% in Liver not koumouliruet and the output after about three hours using kidney .
Indications
Anvifen effective in treating the following diseases:
- neurotic or anxiety-asthenic disorders;
- enuresis, stuttering or tics in children;
- anxiety;
- sleeplessness;
- Meniere's syndrome;
- kinetosis travel sickness;
- vertigo vestibular dysfunction.
In addition, this drug is used as part of a therapeutic treatment abstinence syndrome in alcoholism to arrest the developing somatovegetativnye and psychiatric disorders .
Contraindications
The drug is strictly prohibited to take while pregnancy And between Lactation and at the age of three years. In addition, with extreme caution should be used when Anvifen hepatic insufficiency , and ulcer or erosive lesions of the digestive tract .
Side effects
When you start taking this medicine, patients can tolerate attacks nausea And feel drowsiness, anxiety, irritability, dizziness and headaches . Typically, the most common side effect is considered Anvifena allergic reaction into constituent components of the preparation.
Anvifen, instructions for use (method and dosage)
In accordance with the instructions for use Anvifen take a two- or three-week course. The graph using the drug depends on the type and severity of the disease, and the age groups of patients. Adults as well as children under the age of 14 years may take 250-500 mg. the drug three times a day, with a maximum - 2500 mg. in a day.
Children under 8 years old can take from 50 to 100 mg. the drug three times a day, from 8 to 14 years - a maximum of 250 mg. three times. It is worth remembering that a single daily dose of the drug should not exceed:
- 150 mg. - For children up to 8 years;
- 750 mg. - For children up to 14 years;
- 500 mg. - For patients older than 60 years;
- 250 mg. - For children from 8 to 14 years.
When treating abstinence syndrome Anvifen take three times a day at a dose equal to 250-500 mg. It is noteworthy that the above dose should be gradually reduced to average therapeutic dose for adult patients.
At Meniere's disease or in the treatment of dizziness, related dysfunction vestibular Anvifen take 250 mg. for two weeks, three times a day. To prevent motion sickness, you can take the drug at a dose of 250 mg to 500 mg. one hour before traveling.
Overdose
In case of overdose, the following symptoms: liver, drowsiness, vomiting, eosinophilia, renal dysfunction and nausea. To eliminate the negative effects of the patients washed stomach and prescribed symptomatic treatment and use Activated carbon.
Cooperation
The drug is able to enhance the efficiency of analgesics, antiparkinsonian, hypnotics and antiepileptics , and neuroleptics .
Terms of sale
Exclusively by prescription.
Storage conditions
Keep away from children, light and humidity at temperatures up to 25 C.
Shelf life
3 years.
Cautions
With long-term use of the drug should be monitored for peripheral blood, and regularly check the status of liver . When receiving Anvifena not recommended to drive or engage in activities requiring increased attention and discipline.
Analogs Anvifena
- Afobazol
- Phenazepam
- Phenibut
- Stresam
- Noofen
- Tenotome
By analogues medications include drugs such as the Phenibut , and aminofenilmaslyannaya acid tablets.
Babies
Anvifen not allowed to use in the treatment of children under the age of 3 years.
During pregnancy (and lactation)
The drug is contraindicated.
Reviews Anvifene
As such reviews Anvifene doctors on the Internet does not occur, since doctors are not particularly fond of the format of "virtual" consultations. After all, the proper selection of a drug specialist should examine the characteristics of each patient.
Since the drug is not contraindicated in children, to review Anvifene parents for the most part positive, although some say as a negative factor for side effects. However, the drug is suitable for children and the proper dosage can not cause harm.
Price Anvifena where to buy
Anvifena average price varies depending on the form of preparation and may be at 100 and 180 rubles packing capsules with different capacities.
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