Description overdue on 07/09/2014
- Latin name: Lorinden C
- ATC code: D07BB01
- Active substance: Clioquinol + flumethasone (Clioquinol + Flumetasone)
- Manufacturer: Jelfa S.A., Poland "VALEANT" LLC, Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications for use of the drug
- Contraindications
- Side effects
- Ointment Lorinden C, instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- Reviews
- Price, where to buy
Composition
The preparation comprises active ingredients: flumethasone pivalate and clioquinol As well as petrolatum and white wax.
Product form
Produced Lorinden C in an ointment in 15 g tubes.
Pharmacological action
This medicine has Antimicrobial . antipruritic . antiallergic and anti-inflammatory action.
Pharmacodynamics and pharmacokinetics
The active ingredient of the drug - Flumethasone , It is a synthetic dvuftorirovannym GCS designed for outdoor use. The substance is antiphlogistic . antiallergenic . antipruritic . antiedematous and vasoconstrictive effect. Acting on the skin, the drug can prevent the boundary accumulation neutrophil Reducing inflammatory exudate and produce lymphokines inhibits macrophage migration, reduces infiltration and granulation processes, and so on.
Clioquinol or yodhloroksihinolin relates to derivatives of 8-hydroxyquinoline. Its activity has been reported for yeast, dermatophytes, Gram-positive bacteria. Furthermore, enhanced anti-exudative effect Flumethasone .
Combined exposure Flumethasone and Clioquinol It inhibits the development of various inflammatory and allergic reactions on the skin surface, which can be complicated by bacterial or fungal infections.
Due to the fatty ointment based emollient and water-repellent effect, which provides a protective film that protects the skin from moisture. This preparation is suitable for patients having dry skin and thinning.
After application to the skin it means active substances penetrate through the stratum corneum. Wherein flumethasone pivalate is not absorbed into the bloodstream, it has no systemic action. Increased absorption is due to the frequent use of ointments or applied to extensive areas of skin. It can be expected during the use of funds for the face, skin folds in the ground damages the epidermis, under occlusive dressing. It should be noted that in children the active ingredient is particularly pronounced. Clioquinol in the composition is absorbed through the skin ointments binding to plasma proteins.
Actives negligible metabolized in the skin structure. Advantageously, this process occurs in the liver. Then the components are excreted in bile or urine composition.
Indications for use of the drug
Ointment Lorinden C is prescribed for a variety of skin lesions caused by:
- Gram-positive bacteria;
- dermatophytes;
- yeasts.
Contraindications
This drug is not prescribed for:
- tuberculosis leather;
- viral skin lesions, for example, varicella or Herpes ;
- syphilis with manifestations on the skin;
- precancerous states, and tumors of the skin;
- perioral dermatitis ;
- period after vaccination;
- acne ;
- trophic ulcers Induced varicose ;
- the age of 10;
- hypersensitivity.
Side effects
Use of the drug Lorinden C can cause: burning, striae, folliculitis , Itching and dry skin. Prolonged use leads to the development of: purple, skin atrophy , Telangiectasia, pigmentation disorders, Local hirsutism . When the vehicle is applied to vast areas for a long time, can be shown side effects inherent to the SCS.
Ointment Lorinden C, instructions for use (method and dosage)
According to the instruction in the ointment Lorinden C, it must be applied to the surface of the skin with a thin layer is sufficient. At the initial stage of treatment, daily multiplicity should not exceed 2-3 times. After the relief of acute symptoms is reduced to 1-2 times. The course of treatment an average of 2 weeks.
Overdose
Excessive use of the drug can cause a variety of adverse effects of systemic corticosteroids, such as: Cushing's syndrome . erosive lesions of the gastrointestinal tract, muscle weakness , Suppression of the adrenal cortex, osteoporosis . Such cases call for the elimination of external means and further treatment, depending on the symptoms.
Cooperation
Concomitant use Lorinden C and other external agents is not allowed. When the preparation is applied to large areas of skin, the absorption Flumethasone It can reduce the effect of insulin , Other hypoglycemic agents, antihypertensive drugs, and anticoagulants. In addition, it increases the risk of negative effects of anticholinergics, anabolic steroids, oral contraceptives, androgens, estrogens, antipsychotics, azathioprine, bucarban, diuretics, nitrates, tricyclic antidepressants, antihistamines, cardiac glycosides. Immunosuppressive effect of the drug required to refrain from performing Vaccines and Immunization.
Terms of sale
The pharmacies of prescription ointment.
Storage conditions
The drug should be stored at temperatures up to 25 degrees, in a dark place.
Shelf life
3 years.
Analogs
In modern pharmacology there are analogues of this drug: Flumethasone, Lorinden, Lorinden A. By such means of action include: Dexamethasone, prednisolone, Diprospan, Methylprednisolone etc.
Alcohol
It was found that alcohol consumption does not have any particular influence on the action Lorinden C.
Reviews On Lorinden
As the reviews of Lorinden C - it is an external agent is one of the most popular. It is administered in a wide variety of lesions of the skin, and in most cases, it is very effective.
However, some patients have reported that the positive effect of the drug is stored only for a while, that is simply inhibits the development of undesirable symptoms. After the cessation of the use Lorinden With patients again start to disturb the same violation.
According to experts, such a treatment outcome marked the appointment of external funds without sufficient examination by experts, since often people do not even know exactly what the ointment Lorinden C. Also, many reviews of ointments contain information that patients often use the drug on their own without resorting to the doctor. Therefore, in such cases, it should not be excluded as soon as the temporary cessation of symptoms and development of all kinds of side effects.
Price Lorinden From where to buy
In Moscow pharmacies price ointment Lorinden C for the topical use varies 242-308 rubles.
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