Tranexam

Description overdue on 12/23/2013

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Hemostat . Active ingredient - tranexamic acid . The drug has a specific antifibrinolytic exposure . Active substance inhibits the process of converting plasminogen to plasmin. Medicine Tranexam has hemostatic effects (local and systemic) bleeding caused by elevated levels fibrinolizina (abnormalities of platelet cells, menorrhagia). The drug is able to suppress the formation of specific peptides, kinins, which are involved in the formation of inflammatory responses and allergic reactions.

The drug has anti-tumor, anti-allergic, anti-inflammatory, anti-infective effects. The active ingredient is able to pass the blood-brain, placental barriers; evenly distributed in the tissue structure. The concentration of tranexamic acid in the tissues preserved 17 hours. Under pathological changes of renal tissues in the body cumulated drug. Metabolites are excreted through the kidney tissue. Buy Tranexam can be in the form of a solution, tablets. The vials are manufactured Tranexam 5 ml. Analogs Traneksama: Ekzatsil, Transamcha, Tranexamic acid, Troksaminat. Price Traneksama - 200-300 rubles .

Indications:

Hemostatic tablets Tranexam prescribed as a hemostatic agent at high risk of bleeding against the raised index fibrinolizina (diseases of the liver system, leukemia, cancer, prostate cancer, pancreatic cancer, detachment chorionic, bleeding during and after surgery, hemophilia, post-partum bleeding). Tranexam for bleeding or risk of bleeding is prescribed in the case of local amplification fibrinolizina: hematuria , Bleeding in the digestive system, nasal bleeding, uterine bleeding, tooth extraction in patients diagnosed with hemorrhagic diathesis. Instructions for use Traneksama recommended medicine as an antiallergic agent for dermatitis allergic genesis, hives, eczema and skin rashes caused by exposure to drugs or toxins. In the early stages of pregnancy
Tranexam prescribed for spotting. Application Traneksama with stomatitis, pharyngitis, tonsillitis and laryngitis allows to stop the inflammatory process. The drug can be used in the genesis of hereditary angioedema. Tranexam menstruation to reduce the amount allocated to the blood and prevent bleeding. How Tranexam drinking during pregnancy can be solved only by the doctor.

Contraindications:

Tranexam not prescribed for subarachnoid hemorrhage , Intolerance of tranexamic acid. With thromboembolic syndrome At cerebral thrombosis, myocardial infarction, in tromboflebicheskih lesions deep venous medication prescribed with caution. In severe kidney disease, disorders of color perception tranexamic acid administered after consulting experts. The current component is able to penetrate into breast milk, and therefore it is recommended to stop breast-feeding at the time of hemolytic therapy. Tablets Tranexam during pregnancy may be appointed in cases where the expected benefit to the mother outweighs the potential risk to the health of the child.

Side effect:

Digestive system:   heartburn, disorders of appetite, nausea, diarrhea syndrome. Nervous system:   weakness, visual disturbances, and color vision, dizziness, increased drowsiness. Cardiovascular system:   thromboembolism, thrombosis, chest pain, tachycardia. With rapid intravenous possible development hypotension . Rarely allergic responses are recorded in the form of hives, itching and rash.

Mode of application:

Tablets Tranexam after tooth extraction   administered 3 times a day for 25 mg / kg, the course is designed for 6-8 days. When recurrent epistaxis   the drug is prescribed to 1 gram three times a day, a course - 1 week. The local gain fibrinolizina:   3-4 times a day for 1-1, 5 g of tranexamic acid. After surgery on the cervix: three times a day for 1, 5 grams course - 12-14 days. Therapy profuse uterine bleeding includes receiving traneksana 3-4 times daily for 1-1, 5 grams course - 4 days. Angioedema hereditary origin: 2-3 times a day for 1-1, 5 grams, the rate is calculated individually.

Tranexam The solution is administered intravenously (probably drip and bolus). At a high rate fibrinolizina:   a single dose of 15 mg / kg administered every 8 hours, the infusion rate - 1 ml per minute. Local strengthening fibrinolizina:   2-3 times per day, 250-500 mg. When operational intervention in the bladder after Prostatectomy : During the operation administered 1 gram of the drug; postoperative tranexamic acid administered every 8 hours for 1 gram, the course is designed for 3 days. Then we recommend switching to tablet form of the drug. Patients with bleeding disorders prior to removal of the tooth is administered at a dose of 10 mg Tranexam / kg. After manipulation recommended pills. Dosage Traneksana pregnancy and renal comorbidities system is calculated individually and depends on the level of creatinine. Hemostatic agents like Traneksana during pregnancy can be used only for health reasons.

Special instructions:

Reviews doctors Tranexam uterine bleeding indicate a high hemolytic effectiveness of the drug. It is recommended to be examined by ophthalmologist before and after treatment to assess color perception , Vision acuity to determine the state of the fundus. With hematuria possible blockage of the blood clot urethra and renal pelvis, thereby developing anuria (absence of urination). Tranexam pregnant can be administered in tablet form and in solution form.

Drug Interactions:

The solution Tranexam incompatible with tetracyclines, urokinase , Penicillin, diazepam, hypertensive medicines, blood products, dipyridamole. Possible activation thrombotic events   concurrent therapy with hemostatic agents.