Dimexidum

Description overdue on 10.01.2012

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The active ingredient of the drug Dimexidum - dimethyl sulfoxide . It possesses strong inflammatory action The mechanism of which is to inhibit free radicals   in the inflammation, thereby improving the flow of the processes of metabolism and create favorable conditions for the restoration of normal tissue structure and function of the affected area. In addition to the above effect, analgesic and Dimexidum   antibacterial effect Shows fibrinolytic activity Perfectly penetrates through the skin and superficial tissues, which enables the active use of DMSO in the treatment of joint diseases and other disorders of the musculoskeletal system. In addition to the aforementioned effects of the drug improves the permeability of the skin to other drugs, increasing their effectiveness when applied topically. Influencing microorganisms enhances the permeability of the cell membrane of bacteria, which in turn increases the efficiency of concomitant antibiotic therapy.

Indications:

Applications Dimexidum - surgery, cosmetology, treatment of skin diseases of different etiologies, combustiology, traumatology and rheumatology: DMSO is widely used in the treatment of diseases of the musculoskeletal system , Including the treatment of rheumatoid arthritis , Ankylosing spondylitis ( ankylosing spondylitis ) deforming osteoarthritis   (if there is damage periarticular tissues), in traumatology in the treatment of contusions, sprains, for sucking traumatic infiltrations . Dimexidum also widely used in the treatment of reactive synovitis ; Limited scleroderma . erythema nodosum . systemic lupus erythematosus , Fungal diseases of the feet. It is used for sucking keloid scars. In the treatment of thrombophlebitis Eczema, septic wounds, thermal and chemical burns, sciatica Trophic ulcers and other purulent lesions of the skin. Used Dimexidum and surgery, in particular in dermatology and plastic for the purpose of preserving skin gomotransplantatov (transplant from a living human tissue). In cosmetology used Dimexidum hair as part of masks - in this case, the drug performs several functions. Due to the antimicrobial and fungicidal action of DMSO avoids the use of preservatives. Moreover, the drug acts as an activator for transport of substances through the membrane into the cells and tissues, which increases the rate of penetration of active substances in the tissue of the skin and hair follicles.

Contraindications:

Despite the wonderful therapeutic effect Dimexidum has a glad contraindications. The drug is not prescribed for atherosclerosis. Dimexidum contraindicated in severe disease of the heart and blood vessels (during the development of edema of the lower extremities, with stagnation in the pulmonary circulation, which are accompanied by the addition of inflammatory processes in the respiratory system). It is impossible to prescribe a drug to patients coronary heart disease , Including the angina   and unstable angina in the early stages of post-myocardial infarction. With chronic glomerulonephritis At pyelonephritis   and other diseases of the renal parenchyma, accompanied by organ dysfunction, Dimexidum also contraindicated. In hepatitis of different etiology (including viral and toxic), and cirrhosis When there is a gross violation of work hepatic parenchyma, dimethyl sulfoxide can not appoint. This is also true with respect to the acute stroke ( stroke ), Coma. It is not recommended to prescribe a drug for pregnant and nursing, as well as patients with eye disease ( glaucoma . cataract ). Elderly people should be careful to prescribe Dimexidum and children up to twelve years is better not to appoint.

Side effect:

As a rule, against the use Dimexidum there are no side effects. However, in some cases, still may develop allergic reactions with the skin: erythema, rash, itching, and burning of the skin in the area of ​​application of the drug, the development of dermatitis. Occasionally there is a complication of the respiratory system as a bronchospasm .

Mode of application:

For the treatment of various diseases of the skin are widely used applications with Dimexidum irrigation and drug affected areas .  Depending on the etiology, location and nature of the pathological process will vary concentration of the solution, the multiplicity of therapeutic procedures .  The solution Dimexidum need to moisten the gauze, then apply it to the affected area and leave for 30-40 minutes .  Top closing film, cotton cloth or linen cloth .  The course of therapy, usually 10-15 days .  For the treatment of venous ulcers - use 30-50% solution Dimexidum, in the treatment of eczema and diffuse streptoderma - applications with 40-90% p-rum .  The analgesic effect in the pain syndrome is achieved by using 25-50% solution .  There Dimexidum features of the application in the face and other areas where the skin is extremely sensitive: in these cases is recommended to use a low concentration of the active substance (10-30% solution) .  In cosmetology dimethyl sulfoxide is used to prevent rejection gomotransplantatov 30% Dimexidum as applications used in the area of ​​operation from the first day and throughout the postoperative period .  In surgery Dimexidum administered in the postoperative period for treatment of postoperative wounds in order to prevent inflammatory complications .  Hair mask with Dimexidum used to repair damaged and weakened hair and accelerate hair growth .  For its preparation used natural oil (burdock, castor, etc. . ), A solution of vitamin A and vitamin E, or a tablespoon of tea Dimexidum .  The composition is mixed in a heated state it is rubbed into the hair over the entire length and is rubbed into the roots .  The recommended frequency of use - once a week .

Special instructions:

To the preparation of the patient can be idiosyncrasy .  Often these patients by inhalation of fumes in the air Dimexidum feel faint smell of garlic .  In this case, you need to start therapy with caution and conduct a skin test .  Dimethylsulfoxide be applied to the skin, and if it would lead to redness, itching or a rash occurrence - mean patient Dimexidum and hypersensitivity to the drug must be replaced with another .  Dimexidum hair in the form of masks should be used with care: Do not allow to enter Dimexidum in the eye, in addition, the concentrated solution can be "to burn" the skin of the head, in addition, we can not exclude the development of allergic reactions .  When the last (not only when you use hair masks and all in the course of therapy), the drug should be discontinued and the skin cleaned of traces of the active substance .  Avoid contact with mucous membranes and eyes .  It is recommended to refrain from activities that require a high degree of concentration .

Drug Interactions:

Dimexidum potentiates the effect of ethanol insulin   (with prolonged use of dimethyl sulfoxide reduce the dose of insulin), increases the anti-inflammatory effect acetylsalicylic acid . quinidine , Digitalis, nitroglycerin . streptomycin   and other antibiotics. Dimexidum increases the body's sensitivity to drugs for anesthesia. It is used in combination with non-steroidal agents in the treatment of rheumatic diseases and deformation of the musculoskeletal system. For the treatment of thrombosis commonly used combined use Dimexidum and heparin.