Description overdue on 04/10/2014
- Latin name: Reosorbilact
- ATC code: B05XA31
- Active substance: Potassium chloride + calcium chloride Magnesium chloride + + Sodium Lactate + Sodium chloride Sorbitol + (Potassium chloride + Calcium chloride + Magnesium chloride + Sodium lactate + Sodium chloride + Sorbitol)
- Manufacturer: LLC "Jury-Farm" (Ukraine)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Reosorbilakt
- Contraindications
- Side effects
- Instructions on Reosorbilakt (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
1 ml of solution containing 0, 3 mg potassium chloride 19 mg sodium lactate 60 mg sorbitol , 0, 2 mg magnesium chloride 0, 1 mg calcium chloride 6 mg sodium chloride . Auxiliary component serves water for injection.
Product form
Reosorbilakt available as colorless solution in glass vials, packed in cardboard boxes. Volume: 200, 400 ml.
Pharmacological action
Reosorbilakt is plasma expanders (crystalloid form). The drug detoxification and has protivoshokovym effects. The drug improves blood and alkalify rheology the state of the blood. Combined energy source means comprises a buffer and a balanced ionic composition.
Natrium It is a basic extracellular cation and its volume is directly dependent on the index of the extracellular fluid. Half of all the active elements and extracellular osmotic cations accounted for sodium. Together with Na chloride anion involved in the hemostasis .
Calcium participates in blood clotting , Pulse transmission of nerve bundles, the reduction of muscle tissue. Ca + ions prevents the development of inflammation and edema, reduce the permeability of the vascular walls.
Potassium It is the main intracellular cation and plays a crucial role in the excitability of muscle cells and neurons. K + is involved in metabolic processes not only carbohydrates , but also proteins .
Magnesium inhibits impulse transfer along nerve fibers and activates certain enzymes. Mg + is actively involved in carbohydrate metabolism.
Lactate (anions lactic acid ) Eliminates the effects of acidosis and bind hydrogen ions. Their action is much slower in comparison with bicarbonate, moreover, they do not change the pH.
Sorbitol It is metabolized in the liver and is a system sugar alcohol natural origin. It has osmodiureticheskim effect slows platelet aggregation and is a source of energy independent of the insulin .
Combined tool Reosorbilakt eliminates the phenomenon of acidosis, improves processes microcirculation Normalizes the total volume of fluid in the body, reduces the severity intoxication .
Pharmacodynamics and pharmacokinetics
Sodium chloride briefly increases the total volume of circulating blood throughout the body, but quite rapidly excreted from the vascular bed, increasing diuresis .
Sorbitol accumulates in the hepatic system as glycogen . Quickly included in the tissue metabolism Partly being postponed in skeletal muscle, heart muscle, brain. A small portion of sorbitol derived renal system.
Sodium lactate is reacted with water and carbon dioxide entering the bloodstream. The reaction yields sodium bicarbonate, leading to increased blood alkali reserve . Only half of the sodium lactate is active and reacts, and the rest is not metabolized and unaltered output renal system.
Indications Reosorbilakt
For what it is used: decline in blood viscosity at such vascular diseases as thrombophlebitis and endarteriit . Combined effectively appointed agent to reduce the severity of intoxication at:
- sepsis ;
- burn disease;
- acute blood loss;
- exacerbation of hepatitis B;
- infectious diseases.
Application at Reosorbilakta shock It allows you to adjust hypovolemia and reduce the severity of the general symptoms.
Contraindications
- cerebral hemorrhage ;
- hypertension;
- Individual hypersensitivity;
- cardiac decompensation .
The drug is not prescribed for conditions that can cause bleeding:
- hemorrhagic colitis;
- hepatic pathology system;
- ulcerative lesions of the gastrointestinal tract .
Side effects
Alkalosis, allergic responses .
Instructions on Reosorbilakt (method and dosage)
Allowed only intravenous administration of the drug. The solution can be administered bolus and infusion. In chronic hepatitis volume of the solution for a single injection of 400 ml, with state of shock - 600-1000 ml, in the pathology of arteries and veins - up to 600 ml blood loss - up to 1500 ml.
Instructions for use in pediatric patients Reosorbilakta: children up to 6 years the calculation is made according to the scheme: 10 ml per 1 kg. Children 6-12 years half adult dose is administered.
Overdose
Recorded phenomena alkalosis. It demands the immediate cessation of the infusion.
Cooperation
It is unacceptable simultaneous infusion solutions, which include phosphate anions and carbonate . Reosorbilakt can not be used as a stock solution of the carrier with the introduction of other drugs.
Terms of sale
Leave for prescription form.
Storage conditions
The solution should be stored away from light. Temperature range: 2-25 degrees Celsius.
Shelf life
2 years.
Cautions
The solution must be administered under the supervision level blood electrolytes CBS and indicators, assessing the osmolality of urine, blood and functional state of the hepatic system. Patients with diabetes conducted additional control over glucose levels during treatment.
Analogs
- Reamberin
- Calcium chloride
- Reopoliglyukin;
- Regidron;
- Haemodesum.
During pregnancy (and lactation)
Reliable information available.
Reviews Reosorbilakte (overview)
The drug is well-proven in the treatment of states of shock and severe intoxication. Community health forums leave positive feedback about the drug and indicate a high efficiency, good tolerance of the solution, especially in a slow drip.
Price Reosorbilakta where to buy
The cost of the drug in Russia is 220 rubles. Price may vary depending on the country, the pharmacy chain, sales region. For example, in Kharkov Reosorbilakta price is 40 USD, and in Lugansk - 36 UAH.
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