Description overdue on 09/12/2014
- Latin name: Sedalgin Neo
- ATC code: N02BE71
- Active substance: Codeine + Caffeine + Metamizole + + Paracetamol Phenobarbital (Codeine + Caffeine + Metamizole sodium + Paracetamol + Phenobarbital)
- Manufacturer: Balkanpharma-Dupnitza (Bulgaria)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- Reviews
- Price, where to buy
Composition Sedalgin Neo
Combined sedalgin composition comprises: 10 mg Codeine phosphate 50 mg caffeine 150 mg Metamizolum Na 300 mg acetaminophen , 15 phenobarbital . Additional components: sodium bisulfite, crospovidone, corn starch, microcrystalline cellulose, povidone, Mg stearate, talc.
Product form
Sedalgin Neo is available in tablet form. Flat White tablets have chamfers on both sides, and one side - the risk. Packed in blisters of 5 pieces. Each pack of cardboard is 1 or 2 blisters and instructions from the manufacturer.
Pharmacological action
The tablets have a combined composition and have antipyretic, analgesic, and protivomigrenoznoe vasodilating effects. The drug is capable of eliminating the symptoms Flu , Acute respiratory infections, colds.
Caffeine It stimulates the activity of the brain, particularly the psychomotor centers. The active substance increases efficiency (mental and physical), reduces the severity of fatigue and sleepiness Has analeptic effect, enhances the effect of analgesics.
Codeine It has analgesic effects due to changes in emotional perception of pain, which is achieved by stimulation of the antinociceptive system. Suppression of excitability of the cough center provides the antitussive effect of central origin. In comparison with the active ingredient of morphine less likely to cause respiratory depression, nausea, cramps, constipation (by activating opioid receptors in the intestinal lumen is relaxation of smooth muscle tissue, reduces spasm of the sphincter and decreased peristalsis). Codeine is able to enhance the effect of analgesics.
Paracetamol It is a non-narcotic analgesic orientation. The mechanism of action by blocking cyclooxygenase-1, 2 in the nervous system. Antipyretic and analgesic effect is achieved due to the impact of the centers of thermoregulation and pain.
Metamizol Na It refers to the group of NSAIDs. It has antipyretic, analgesic effect. In respect of smooth muscles of biliary and urinary tract observed antispasmodic effect.
Phenobarbital sedative, antiepileptics, muscle relaxant and sedative effects.
Pharmacodynamics and pharmacokinetics
Indicators can not be estimated because of the combined structure of a medicament.
Indications
- hyperthermia;
- unadjusted neuritis;
- migraine headaches ;
- sciatica;
- pain syndrome myalgic origin;
- dental pain;
- pain rheumatism ;
- postoperative pain;
- post-burn pain;
- chronic pain syndrome;
- dysmenorrhea of unknown origin;
- traumatic pain.
Contraindications
- peptic pathology duodenum ;
- bleeding diathesis ;
- anemia;
- pregnancy ;
- renal system diseases;
- bronchial asthma ;
- Individual hypersensitivity .
Side effects
Occasionally there is discomfort in the epigastric region, allergic responses , Thrombocytopenia (decrease in the number of blood cells - Platelet ) dizziness . When long-term therapy may develop renal failure and renal system, possibly more frequent asthma attacks. When abrupt cancellation of medication recorded withdrawal symptoms manifest mainly headaches . Long-term use may be associated with a gradual decrease in the effectiveness of the drug.
Nervous system:
- irritability;
- tremor of the extremities ;
- headache;
- fatigue;
- anxiety;
- incoordination.
Cardiovascular system:
- agranulocytosis;
- arrythmia;
- hypotension;
- heart palpitations;
- hemolytic anemia.
The digestive tract:
- constipation;
- epigastric pain;
- vomiting;
- anorexia;
- dry mouth;
- diarrheal syndrome;
- changes in the liver.
Rarely seen bronchospasm. When registering other adverse reactions should be consulted doctors and self Sedalgin removal of the drug.
Instructions for use (method and dosage)
Sedalgin taken orally. Tablets need to drink water. Instructions for use Sedalgin Neo: 1 tablet per day. On the day can take no more than 6 tablets.
Overdose
High doses inhibit reflex responses, cause dry mouth, dizziness expressed develops asthenic condition. In severe cases registered depression of the respiratory center , loss of consciousness. First aid includes measures to clean the digestive system from the remnants of the medication, appointment sorbents . Posindromnoe treatment is carried out in specialized clinics.
Cooperation
Anxiolytics, sedatives and all medications that suppress the nervous system can lead to increased sedation Sedalgin Neo and oppression of the respiratory center (life-threatening). The drug increases the influence of alcoholic beverages on psychomotor reactions. Metamizol displaces hypoglycemic drugs, indirect anticoagulants, indomethacin, corticosteroids in association with proteins, increasing their activity. Oral contraceptives , Antidepressants and allopurinol increase the toxicity metamizole Na, changing its metabolism in the hepatic system. The action of the active ingredient is reduced when taking inducers of hepatic microsomal enzymes. Increased toxic effects observed with other non-narcotic analgesics.
Terms of sale
The composition of the drug include Codeine, which has recently refers to a group of drugs, prescription, so Sedalgin Neo can now be purchased only by presenting a prescription medical form listing all the components of the drug to the INN.
Storage conditions
The manufacturer recommends to keep the tablets in a temperature range of 15-25 degrees, limiting the admission of children to blister.
Shelf life
3 years.
Cautions
When you receive the tablets for more than 7 days required control performance work systems and the state of hepatic peripheral blood. Sedalgin Neo could cause distorted results Doping Control . At the "acute abdomen" medication can interfere with the diagnosis of masking the main symptoms of the disease. The risk of allergic responses increased in patients suffering from bronchial asthma, hay fever.
Analogs
Rinzasip
Kaffetin Light
Kaffetin
Rinikold
Koldakt Flew Plus
Rinzai
Tsefekon
Antigrippin
Tylenol
Coldrex
Theraflu
Flyukold
Farmatsitron
Solpadein
Paracetamol
Fervex
Efferalgan
Panadol
- Sedan-M ;
- Kvintalgin ;
- Santoperalgin .
Babies
In pediatric patients may be given only 14 years old.
Reviews Sedalgin Neo (opinion of the patients)
You can find a variety of responses to the drug. Many patients point to the development of dependence on the pills in the long reception associated with severe pain. Someone said that it is the only means of fleeing from headaches at change of weather. In general, the drug has proven itself as a remedy for pain.
Price Sedalgin Neo where to buy
Sedalgin Price depends on the number of tablets in the package, the sales region. Buy in Moscow can be over 10 tablets of 165 rubles; 20 - 250 rubles. Sedalgin Neo is a prescription medication and released only on presentation of a prescription, so you can not buy in the Internet pharmacies.
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