Albumen

Description overdue on 10-10-2011

Related Articles:

• Reviews of preparation Dafnedzhin
• Reviews for erythromycin ointment for acne
• Price Valsacor
• Cefuroxime

Tweet

The main active substance - albumin . It is a plasma substitute, Natural protein . blood products . Included in the protein fraction of human. AT plasma   healthy person among all of albumin is 60%. Albumin includes 20 amino acids. It is synthesized in the liver. The main objective of albumin - maintaining colloidal oncotic blood pressure . Mortar preparation prepared from placenta plasma by fractionation. Albumin is represented by a transparent liquid, the color of which varies from light brown to yellow.

Albumin is effectively used for correction hypoalbuminemia   various etiologies, recovery of oncotic, colloidal blood pressure hemodynamic disturbances   (central, peripheral), water and electrolyte balance, improves the absorption of drugs, has detoxification effects. Albumin binds and transports fatty acids, pigments, drugs, metal ions, inactivates toxins .

Dosage Form:

The solution in vials (10% - 100 ml). Introduction of intravenous drip / jet.

Indications:

The main purpose of the drug - hypoalbuminemia . hypoproteinemia , Decreased oncotic pressure (tissue swelling), nephrotic syndrome (due to nephritis). Albumin is effective in severe burns, acute hepatic necrosis, acute liver failure, liver disease with the disorder albuminsinteziruyuschey functions hyperbilirubinemia , Hemolytic disease of the newborn, ascites . hemodialysis , Medical plasmapheresis , Acute respiratory distress syndrome.

Use of albumin at unreasonably chronic nephrosis Since the drug in a short period of time is eliminated renal system, without affecting renal damage. Quite rarely used in medicines acute nephrosis .

Contraindications:

Bleeding, hypertension, intolerance to albumin, the risk of overload volemic (with chronic anemia, heart failure, renal failure). It is forbidden to use the muddy, frozen dissolved. Used, damaged, cracked, pre-printed bottles are not used to prevent separation of the bacterial infection.

Side effect:

In most cases, administration of the drug solution in compliance with all recommendations of the causes of complications and adverse reactions. Rarely develop allergies (transfusion dissolved stopped administered cardiac, antihistamines, vasopressor drugs glucocorticosteroids ). Adverse reactions may be due to a high content of protein in the excessive infusion preparation.

Special instructions:

To prevent overloading volimicheskoy blood system requires careful study of patients prior to administration of the drug. Dehydration albumin transfusion in complex with brine (albumin first, and then brine). The solvent may be a 5% solution of glucose, 0, 9% NaCl. If massive blood loss in acute drug can be poured together with the red cell mass, in rare cases - with whole blood. After transfusion colloid (positive oncotic activity) may be bleeding, requires monitoring by the vascular surgeon.

Drug Interactions:

Albumin is fully compatible with the red cell mass of whole blood by standard carbohydrate, electrolyte solution for the on / in infusions. Do not mix the drug with solutions of amino acids, hydrolysates , Alcohol-containing mixtures.