Suprastin

Description overdue on 09.12.2011

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A drug against allergies . Active ingredient - Chloropyramine . The principle of action of the drug based on blocking the histamine H1 receptor. Suprastin has antiemetic, m-anticholinergic, antihistamines, sleeping pills and sedative effects. Peripheral cholinoblocking activity and antispasmodic effects expressed moderately. Suprastin begins its effective action 15 minutes after application, the maximum effect was an hour, duration up to 6 hours. Metabolism hydrochloride Chloropyramine comes liver, metabolic products derived renal system. Produced in tablet form, as a solution for intramuscular administration, intravenous administration. The solution is discharged in a dark bottle.

Indications:

Suprastin prescribed for angioedema , Urticaria, allergic rhinitis, serum sickness , Allergic conjunctivitis, skin ulcers, contact dermatitis, eczema in the acute and chronic form of allergy to insect stings, medication allergy Food allergy.

Contraindications:

Suprastin not apply in case of intolerance Chloropyramine, bronchial asthma in pristupnaya period, pregnancy, breastfeeding. When prostatic hypertrophy, urinary retention, angle-closure glaucoma, functional disorders of the kidney and liver systems, diseases of the heart and blood vessels, elderly patients Suprastin used with caution.

Side effect:

Nervous system : euphoria , Headaches, tremor of limbs, nervous agitation, dizziness, fatigue, hypersomnia. Digestive system : Epigastric pain, eating disorders, disorders of the chair, dyspepsia , Dry mouth, abdominal discomfort. Cardiovascular system : Drop in blood pressure, arrhythmia (rare), and tachycardia. Forming Organs : agranulocytosis , Reduction in the number of white blood cells. During the period of use of the drug may develop photosensitivity , Increased intraocular pressure, muscle weakness, difficulty with urination.

Mode of application:

A tablet form of the drug is taken three times a day to 25 mg. Suprastin children 1-6l administered in a dose of 6 25 mg (1/4 tablets) twice daily. Children from 6 years - ½ tablet twice a day. In the absence of side effects of the dosage can be increased by the maximum amount of drug is calculated from the rate of 2 mg / kg. Suprastin tablets washed down with water, do not chew, taken with food. Solutions of the drug is administered mostly intramuscularly. Intravenous injection is allowed only in case of acute disease under medical supervision. Intramuscularly administered to adults 20-40 mg. After the relief of acute attacks of intravenous administration of the drug treatment continue intramuscular injections followed by transition to a tablet form. In the pathology of renal dose reduce by half.

Overdose:

The use of high doses of the drug is accompanied hallucinations .   ataxia , Anxiety, convulsions, loss of coordination, mydriasis . athetosis . In infants overdose manifest fixed dilated pupils, dry mouth, anxiety, agitation, sinus tachycardia , Reddening of the facial skin, fever , Urinary retention, coma. During the first 12 hours is necessary to carry out gastric lavage, appoint Activated carbon , To conduct resuscitation. No specific antidote.

Special instructions:

Depletion, elderly patients Suprastin administered under the supervision of the attending physician. During an anti-allergic therapy should abandon the use of alcoholic beverages. One tablet contains lactose   at a dose of 116mg, which can cause adverse reactions in people with malabsorption galactose, glucose. Suprastin affect the management of complex machinery, transport, performance of work requiring increased attention. Tablet form of the drug available without prescription. Solutions suprastin released only with the doctor's prescription form. The storage temperature of 15-25 degrees Celsius above zero, away from children.

Drug Interactions:

Action simpatolitikov, atropine, tricyclic antidepressants . MAO inhibitors , Analgesics, tranquilizers , Sedatives enhanced by concomitantly with suprastin. Benzedrine . caffeine   reduce the inhibitory effect of the drug on the nervous system.