Nasobek

Description overdue on 08/11/2014

• Latin name: Nasobec
• ATC code: R01AD01
• Active substance: Beclomethasone (Beclometasone)
• Manufacturer: Teva Pharmaceuticals Industries, Israel

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions on Nasobek (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Reviews
• Price, where to buy

Composition

As part of a single dose of the spray is the active substance ( BDP ) + 50 ug adjuvants ( phenylethanol anhydride, dextrose, sodium carboxymethylcellulose, water, benzalkonium chloride, polysorbate, microcellulose, hydrochloric acid ).

Product form

Spray is a suspension, a white, opaque, without inclusions. In bottles of 100, 180 and 200 doses.

Pharmacological action

Anti-inflammatory, anti-allergic   means. Relieves swelling.

Pharmacodynamics and pharmacokinetics

The active ingredient of the drug is a synthetic glucocorticosteroid . It stimulates reproduction lipomodulina Which is an inhibitor of the enzyme phospholipase A   and delays the process of synthesis arachidonic acid . Thus, there is a reduction of the inflammatory exudation   and synthesis lymphokines , Slowing the process of regional clusters neutrophil cells .

Inhibits the processes Infiltration   and granulation   thanks to the ability beclomethasone   oppress migration macrophages . Swelling subsides, less mucus is produced, mucociliary transport   improving.

The tool is well tolerated, even in the very long-term use. Relief of symptoms occurs within paru- three days after the start of the reception.

When administered by inhalation, does not have high absorptive capacity. A small number of agents to infiltrate GI It is destroyed by the liver. Half of the substances excreted from the body within 15 hours, up to 90% of the active substance is bound to plasma proteins. Withdrawal of the drug in the feces and slightly through the kidneys.

Indications

The medicine is prescribed for treatment rhinitis , including vasomotor   and allergic .

Contraindications

• allergy For any component of the drug;
• hemorrhagic diathesis;
• first trimester of pregnancy;
• tendency to bleed from the nose;
• fungal or viral infection;
• tuberculosis   respiratory tract or organs.

The drug is contraindicated in children under 6 years.

You should be cautious when:

• glaucoma ;
• hypothyroidism ;
• ulcers and cuts in the nasal septum;
• in the second and third trimester of pregnancy;
• during Lactation ;
• at amebiasis ;
• liver disease;
• recently occurred myocardial infarction ;
• after surgery or trauma of the nose.

Side effects

Rarely can occur:

• hives , Skin rashes, angioedema;
• candidiasis ;
• headache, weakness, drowsiness, distortion of taste and smell;
• dryness of mucous membranes of the mouth and nose bleeding, cough, burning and itching in the nose, rhinorrhea .

There are cases of:

• ulcers on the nasal mucosa and perforations   partitions;
• reducing the rate of growth and thinning of the bones in pediatric patients;
• conjunctivitis . Glaucoma , Visual impairment.

Instructions on Nasobek (method and dosage)

Spray used intranasally .

At the age of 12 years, at 1-2 doses administered to each nostril two times per day.

For children from 6 to 12 years the daily dose up to 400 mg. As a rule, take 1 dose in each pass of 2 times a day.

Treatment means is continued until until such improvement in health.

According to the instructions for use Nasobeka before its first application (or after a long break) the vial should be shaken.

Released several doses in the air, until the white cloud.

Then, placing the nozzle sprayer between the middle and index fingers, exhale.

Clamp one finger free nasal passage and the spray medicine in the other. Spraying is done on the breath, exhale through the mouth produce.

You must repeat the above steps for the other nostril.

After the procedure, clean the spray gun nozzle with a damp cloth or a clean handkerchief.

Additionally, it is recommended to clean the applicator, at least 1 time per week. The nozzle must be removed, rinse with warm running water, dried and re-use vial.

Overdose

Prolonged use of high doses may occur   hypercorticoidism . It is gradually reducing the dose, stop taking the money.

Cooperation

When combined with phenobarbital, phenytoin, rifampin, glutetimid   and E fedrinom, beclomethasone reduces their therapeutic properties.

Simultaneous treatment with agonists, antithrombotic agents, digitalis preparations, oral preparations gipoglikimicheskimi   and Indapamide It leads to increased risk of side effects, such as the one and the other side.

The drug reduces the effectiveness of Isoniazid .

The drug enhances the effect of antiasthmatics   and system GCS .

Terms of sale

It requires a prescription.

Storage conditions

Keep out of the reach of small children. Temperature range 10 to 25 degrees.

Shelf life

4 years. If the bottle has been opened, it should be used no more than 3 months.

Cautions

Avoid contact with the eyes.

The effect of the medication is not immediately, sometimes it can take up to 7 days to reach it. During this time, do not try to reduce the dosage or stop taking money.

Apply the medication to the affected mucosa until complete healing of wounds and ulcers prohibited.

It should pay particular attention to people with increased risk of failure adrenocortical   and young children.

Be careful in the management of transport and mechanisms during treatment.

Analogs Nasobeka

Match code ATC 4th level:

• Tafen Nazal
• Polydex with phenylephrine
• Avamys
• Fliksonaze
• Nasonex
• Nazarel
• Bekonaze

Russian analogues medications: Beklospir   and Eco-Beklazon .

Other analogues on the market: Maple, bekotid, Beklat, Rinoklenil, Aldetsin, Beklorin .

What to choose, Nasonex   or Nasobek ?

Nasonex is used to treat sinusitis . rhinitis   (allergic rhinitis). It can take the children have two years of life, it is believed that it is less harmful. Nasobeka cost much lower than that of its counterpart. In any case, the question of replacing or drug discontinuation should be solved together with the attending physician.

Reviews Nasobeke

Reviews Nasobeke mostly positive. Many are struggling with this tool not only Allergies But with symptoms sinusitis When vasoconstrictor drugs do not help. In conjunction with antibiotics   medication to cope with sinusitis.

Some patients have acquired dependence on the vasoconstrictor, fight it with the help of Nasobeka. Side effects are rare, many people like the flower smell the drug and convenient form of release. Also it attracts a relatively low cost of the drug.

Price Nasobeka where to buy

Price Nasobeka is about 180 rubles per bottle containing 200 doses.

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