Pantsef

Description overdue on 09/28/2014

• Latin name: Pancef
• ATC code: J01DD08
• Active substance: Cefixime (Sefixime)
• Manufacturer: Alkaloid AD (Republic of Macedonia)

Photos of the drug

Tweet

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Pantsef (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

One tablet   It contains the active substance tsefeksima - 630 mg; Other ingredients: magnesium stearate, hypromellose, pregelatinized starch and corn, titanium dioxide, MCC, calcium dihydrogenphosphate, sodium lauryl sulfate, gelatin, macrogol 4000.

Granules   (60/100 ml) to prepare a slurry containing the active ingredient tsefeksima   (As tsefeksima trihydrate) 1, 208-1, 351 and 2-2, 238 g Further ingredients: Xanthan gum, sucrose, orange flavor, sodium benzoate.

Product form

The drug is released in the form of granules for the preparation of suspensions for oral use and in tablet form. The perforated aluminum blister contains 5 or 6 tablets. In a cardboard blister pack is 1 (6 tablets) or 2 blisters of 5 tablets.

The granulate produced in dark bottles with special lid and aluminum lining. Each bottle is equipped with a control of the first autopsy. Bottles 60 have a volume of 100ml.

Pharmacological action

The drug Pantsef It is antibiotic   and it has a broad spectrum of antimicrobial action. It affects the synthesis of bacterial cell walls, which leads to the death of gram-positive and gram-negative microorganisms. Antibiotic use in pediatric patients. Marked antimicrobial action Pantsef suspension allows to position the drug as antibiotic for children .

Pharmacodynamics and pharmacokinetics

Active ingredient cefixime   third generation antibiotic is for oral (oral) receiving and exhibits antibacterial activity against most gram-negative bacteria and gram-positive microorganisms. The medicament resistant to beta-lactase gram-positive and gram-negative microorganisms. Active substance gives bacterial cell wall synthesis of agent that leads to their death. Resistance to a drug is formed slowly.

Indications

The drug is prescribed for infectious and inflammatory diseases Caused by susceptible microorganisms cefixime trihydrate.

Urinary Tract Infections:

• cervicitis ;
• urethritis gonococcal origin .

Infections of the respiratory system:

• pneumonia ;
• bronchitis   (for acute, chronic form);
• tracheitis .

Infections of the upper respiratory tract:

• sinusitis infectious origin ;
• tonsillitis ;
• otitis media (middle, outside) ;
• pharyngitis .

The drug is prescribed for acute intestinal infections .

Contraindications

Antibiotics are not prescribed in case of hypersensitivity to the penicillins   and cephalosporins . Be wary of children under six months, patients of advanced age.

Side effects

The digestive tract:

• anorexia;
• dry mouth;
• diarrheal syndrome;
• vomiting;
• nausea;
• goiter;
• epigastric pain;
• candidiasis;
• hyperbilirubinemia;
• bloating;
• jaundice.

Rarely recorded:

• glossitis ;
• stomatitis ;
• pseudomembranous enterocolitis .

Hematopoietic system:

• thrombocytopenia;
• hemolytic anemia;
• leukopenia;
• neutropenia.

Nervous system:

• migraine headaches;
• dizziness.

Urinary system:

• nephritis (interstitial form);
• discomfort when urinating.

There are allergic responses :

• flushing of the skin;
• hives;
• itching;
• fever;
• eosinophilia.

Instructions for use Pantsef (method and dosage)

A tablet form of the drug   taken orally in adults and children (twelve years) - 8 mg per 1 kg weight of the patient within 24 hours or 4 mg / kg twice a day. The maximum dosage of 400 mg per day of the antibiotic. In uncomplicated gonorrhea once taking 400 mg. The duration of antimicrobial therapy is 7-10 days.

Patients who stay on hemodialysis And in severe renal pathology system dose reduced by 25%.

In some cases, appointed Pantsef suspension.   Instructions for Use: For adults and children older than twelve years (body weight 50 kg), recommend the use of a daily dose of 400 mg once a day or 4 mg / kg, 2 times a day.
Babies   from five to eleven - 8 mg per 1 kg once every 24 hours or at 4 mg per 1 kg every 12 hours, i.e. 6-10 ml suspension 24 hours. Children from two to four years to designate 5 ml, and from six months to a year - 2, 5-4 ml of suspension. The duration of treatment of seven - ten days.

Preparation of slurry   It carried out immediately before use. The vial with powder shake, turning it a couple of times. Add 40 ml of boiled, cooled water in two stages, wherein after each must shake the vial to form a homogeneous liquid, hereinafter for 5 minutes the suspension was allowed to stand. For convenient dosing using a special measuring cap. The finished suspension before use, you must shake.

Overdose

The use of high doses of the drug leads to increased side effects previously described. Recommend stomach wash, designate chelators,   posindromnuyu conduct therapy. Peritoneal Dialysis   and dialysis are not effective in overdose.

Cooperation

Diuretics   and blockers tubular secretion   cefixime trihydrate prevent excretion by the kidneys, which leads to increased toxicity. Antacids   slow down the absorption of the drug. If used simultaneously with Pantsef Carbamazepine , The increase in the blood concentration of carbamazepine. The active ingredient of the drug reduces Pantsef prothrombin index , Reinforcing the action anticoagulants .

Terms of sale

Sold by prescription only physician.

Storage conditions

Temperature of 15 to 25 degrees Celsius in a dark, dry place. Keep away from children.

Shelf life

The suspension can be stored after preparation to 14 days. The drug in the package - 3 years.

Cautions

If a patient Sensitivity   to penicillin antibiotics, you may be an allergic reaction to the drug. In this case, you need to stop taking and take appropriate action.

Perhaps violation microflora As the use of other antibiotics, which may lead to pseudomembranous colitis   and diarrhea.

Also, during treatment can psevdolozhnaya reaction urine ketonuria , Glucose. Rarely recorded false positive Coombs' test .

Analogs Pantsefa

Match code ATC 4th level:

• Cefixime
• Tseforal Soljutab
• Klaforan
• Cefodox
• Supraks Soljutab
• Ceftriaxone

Structural analogues: Iksim Lupin . Supraks . Tsemideksor . Cefixime . Tseforal Soljutab . Tsefspan .

During pregnancy and lactation

With pregnancy   the drug can be used only in cases where the benefit to the mother greater than the risk to the fetus. When used during breast-feeding should be stopped lactation .

Reviews Pantsefe

In medical sites and forums are only positive reviews about Pantsef. The antibiotic is well tolerated, and has established itself as the best tool in the treatment of infectious diseases. Suspension for children   actively used in pediatric patients because of the low severity of adverse reactions.

Pantsef or Supraks?

Supraks is also the active ingredient that Pantsef. But there is a perception that Pantsefa less pronounced side effects and allergic to it happens much less frequently.

Price Pantsefa where to buy

The cost of drug depends on the sales region, the dose of the active substance and the release forms. The suspension is about 480 rubles. The minimum cost of an antimicrobial agent - 450 rubles.

Price in Pantsefa tablet form   on average - 785 rubles. Cost suspension for children Pantsef (100 mL) is approximately 570 rubles. In any pharmacy of your city, you can Pricing and purchase the drug.

Get the best price and buy