Parkinsonism is the most common disease in the world among the elderly, suffer them equally men and women. Although the first bells may appear in 40 years and even before, as, for example, the boxer Muhammad Ali. The main manifestation - tremors and involuntary movements of the arms and legs, which are due to the withering away of neurons in certain areas of the brain.
Causes of this disease are not fully known - and atherosclerosis of the brain and injuries. Home Version - specific genetic defects that manifest themselves under certain circumstances. Treated this disease until recently largely symptomatic - neurological drugs and the means to improve cerebral circulation. But a few days ago the Austrian scientists have started clinical trials in humans the world's first vaccine against Parkinson's disease. This is the final stage of the research, then animal testing has been successful.
An experimental drug has been developed PD01A Austrian biotech company AFFiRiS, according to Medical News Today. The target graft is alpha-synuclein protein, which is associated with mutations in certain genes involved for the development of Parkinson's disease. The introduction of a vaccine designed to stimulate the production of antibodies to this protein.
To participate in the first phase of clinical trials were selected 32 patients with Parkinson's disease. During the first phase of research experts check the safety of vaccination for the human body and its portability. If all goes well, then in the next five years can give a "green light" for mass production and use of vaccines.
BTW
The main symptoms of Parkinson's disease:
1. Stiffness and slowness of movement, usually begin in the right half of the body, and then, after a while, gradually capture the other side.
2. Power of all muscles - increased tone. It is involuntary and eventually the patient limbs gradually bent, back ssutulivaetsya. Neuroscientists call this position "posture of the petitioner."
3. gait becomes shuffling and mincing. The man shifts the center of gravity, he loses his balance and even falls.
4. When a patient does not move his arms and shaking his chin clearly, but the tremor during movement was observed.
5. The patient has "frozen" face, he rarely blinks.
6. Despite the fact that the intellect remains, slowed thinking and attention.
7. associated disorders are: reduction of smell, constipation, urination disorders.
Source
Industry News
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